Faculty, A–Z
Anne Baranger, Professor
Bioorganic basis of RNA-protein recognition; recognition of non-helical RNA structures by peptides and small molecules; design of RNA-protein complexes using the RRM domain; small molecule control of RNA-protein complexes
Lin-Feng Chen, Assistant Professor
Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways.
Robert M. Clegg, Professor
Multifarious molecular structures, conformational changes, thermodynamic stabilities, and functions of nucleic acids and protein–nucleic acid complexes
H. Edward Conrad, Professor Emeritus
Structure, metabolism, and biological activities of heparin and heparan sulfate
Antony R. Crofts, Professor Emeritus
Structure–function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere
John E. Cronan, Jr., Alumni Professor and Head of Microbiology
Biosynthesis, regulation, and function of membrane lipids and fatty acid-derived coenzymes
Rutilio A. Fratti, Assistant Professor
Membrane microdomain assembly and membrane fusion
Robert B. Gennis, Professor and Henry E. Preble Chair
Membrane enzymes involved in energy transduction; electron transport chains in E. coli and Rb sphaeroides
John A. Gerlt, Professor and Gutsell Chair
Mechanisms of enzyme-catalyzed reactions; functional genomics; directed evolution and rational design of "new" enzymes
Michael Glaser, Professor Emeritus
Growth factor and hormone regulation of myelin synthesis; membrane domains and signal transduction
Govindjee, Professor Emeritus
Oxygenic photosynthesis, history of photosynthesis research, and photosynthesis education
Taekjip Ha, Professor
Developing and using single-molecule fluorescence microscopy and nano-mechanical manipulation tools for molecular biophysics research
Lowell P. Hager, Professor Emeritus and Member, National Academy of Sciences
Oxidative enzyme mechanisms and protein chemistry
Paul J. Hergenrother, Associate Professor
Using small molecules to modulate programmed cell death; identification and use of compounds with novel anticancer, antineurodegenerative, and antibacterial properties
Raven H. Huang, Associate Professor
Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair
Eric Jakobsson, Professor Emeritus and Director, National Center for Biomimetic Nanoconductors
Computational studies of biological membranes: the physical and chemical bases of life at the interface
Neil L. Kelleher, Professor
Enzymology and "top down" proteomics: translating the high performance of Fourier-transform mass spectrometry into biological insight
David M. Kranz, Professor and Philip A. Sharp Professor
Structure, function, and engineering of T-cell receptors; molecular basis of immune recognition and autoimmune diseases; tumor targeting with bispecific agents
Deborah E. Leckband, Professor
Molecular mechanisms of cell adhesion; cell engineering
Yi Lu, Professor
Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as antiviral pharmaceutical agents or as metal ion biosensors
Susan A. Martinis, Professor and Interim Head of Biochemistry
RNA structure and function, RNA-protein interactions, chemical mechanisms of biological reactions, protein synthesis, tRNA synthetases
James H. Morrissey, Professor
Regulation of protease cascades; structure–function analysis of protein-phospholipid interactions and how they contribute to catalysis
Satish K. Nair, Associate Professor
X-ray crystallography, gene regulation, DNA-protein interactions
George W. Ordal, Professor Emeritus
Investigation of the molecular basis of excitation and adaptation during chemotactic sensory transduction in bacteria
Chad M. Rienstra, Assistant Professor
Solid state nuclear magnetic resonance (SSNMR), including the development of new pulse sequence methodology and instrumentation, and application to studies of protein structure and dynamics
Mary A. Schuler, Professor
Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases
Bradford S. Schwartz, Professor and Regional Dean, College of Medicine
Regulation of the initiating steps of protease cascades
David J. Shapiro, Professor
Estrogen action: from gene transcription and mRNA metabolism to inflammation, apoptosis and immune surveillance
Scott K. Silverman, Associate Professor
DNA as an enzyme; DNA as a structural constraint; DNA as a sensor component
Stephen G. Sligar, Director of the School of MCB, I.C. Gunsalus Professor of Biochemistry, University Scholar
Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome–proteome analysis, macromolecular signaling and the biological details of cell migration.
Maria Spies, Assistant Professor
Biochemical mechanisms and function of DNA helicases and DNA motor proteins; mechanistic aspects of protein–nucleic acids and protein–protein interactions; homologous genetic recombination; DNA repair; molecular motors
M. Ashley Spies, Research Assistant Professor
Enzyme mechanisms; kinetic isotope effects; kinetics; origins of enzyme catalytic power; bioorganic chemistry; amino acid racemases and epimerases; pyridoxal-5'-phosphate (PLP) chemistry and enzymology
Robert L. Switzer, Professor Emeritus
Regulation of bacterial gene expression by transcriptional attenuation
Emad Tajkhorshid, Assistant Professor
Computational studies of membrane channels and transporters
Wilfred A. van der Donk, Professor
The understanding of enzymatic transformations that are of pharmaceutical importance
Colin A. Wraight, Professor
Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions
Huimin Zhao, Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering
Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis