MIP: The School of Molecular and Cellular Biology at the University of Illinois at Urbana-Champaign

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Milan Bagchi.

Welcome to Molecular and Integrative Physiology

In this post-genomic era, physiology is uniquely poised at the nexus between molecular function and whole animal integration with the goal of understanding how the functions of thousands of encoded proteins serve to bring about the highly coordinated behavior of cells and tissues underlying physiological functions in animals and how their dysfunction may lead to disease.  Research and graduate training in the Department of Molecular & Integrative Physiology is focused on understanding the regulation and function of gene products at multiple levels of biological organization, from molecules and macromolecular complexes to cells, tissues, and whole organisms. With the tools of molecular genetics and modern systems biology, physiologists are at the forefront of dramatic advances currently occurring in life and biomedical sciences. Advanced training in molecular and integrative physiology will provide the necessary foundation to prepare for a career in this exciting area of functional biology.

Milan K. Bagchi, Head

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MIP News

New Technology Helps Detect Epigenetic Changes Important to Disease

Professor of Molecular and Integrative Physiology Ann M. Nardulli and colleagues at the University of Illinois and the Mayo Clinic have created a new technique for identifying methylated DNA, a modification to our genetic material that has been shown to correlate with the disease severity and metastasis ability of various types of cancers. Read more...

William Bruce, Caroline Johnson, and Keith Whitlock selected for Mayo Summer Undergraduate Research Fellowship

William Bruce, Caroline Johnson, and Keith Whitlock, outstanding students from the School of Molecular and Cellular Biology, have been selected for three of the five slots specifically reserved for University of Illinois students in the Summer Undergraduate Research Fellowship (SURF) Program at the Mayo Clinic. Read more...

The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors

In a new finding published in Nature Chemical Biology, Research Scientist Gisela Cymes and Associate Professor of Molecular and Integrative Physiology, Biophysics, and Neuroscience Claudio Grosman applied single-molecule electrophysiology to elucidate the properties of the ring of acidic side chains that catalyzes the flow of cations through the nicotinic acetylcholine receptor channel. Read more...

Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons

Tongfei Wang, Gubbi Govindaiah, Liana Artinian, and Charles Cox of the Department of Molecular and Integrative Physiology are co-authors of a new paper in Sciencexpress. Professor of Molecular and Integrative Physiology and Cell and Developmental Biology Martha Gillette is corresponding author. Read more...