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Claudio Grosman.

Welcome to Molecular and Integrative Physiology

In this post-genomic era, physiology is uniquely poised at the nexus between molecular function and whole animal integration with the goal of understanding how the functions of thousands of encoded proteins serve to bring about the highly coordinated behavior of cells and tissues underlying physiological functions in animals and how their dysfunction may lead to disease.  Research and graduate training in the Department of Molecular & Integrative Physiology is focused on understanding the regulation and function of gene products at multiple levels of biological organization, from molecules and macromolecular complexes to cells, tissues, and whole organisms. With the tools of molecular genetics and modern systems biology, physiologists are at the forefront of dramatic advances currently occurring in life and biomedical sciences. Advanced training in molecular and integrative physiology will provide the necessary foundation to prepare for a career in this exciting area of functional biology.

Claudio Grosman, Head

MIP News

On Saturday, May 16, 2020, the School of Molecular and Cellular Biology celebrated its outstanding graduates with a virtual convocation. The ceremony included a slide show about students and their future plans, shout-outs from MCB faculty, and remarks from MCB Director Milan Bagchi and Tina Knox, assistant director for advising and recruitment. The event concluded with a performance by the Marching Illini.
Epilepsy is a common chronic brain disorder that affects 3% of the world’s population. In epilepsy, excessive electrical activity in neurons makes them prone to misfire and trigger seizures. Nearly half of epilepsy cases are caused by genetic mutations in a variety of proteins including ion channels. Usually, seizures in epilepsy associated with genetic mutations begin from birth or childhood, thereby affecting children’s cognitive abilities and increasing their chances of developing disorders like autism or depression. Some patients with genetic epilepsy cannot be treated with existing anti-epileptic drugs, so research is needed to create new drugs to treat them.
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