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Biochemistry Faculty
| [+][^] | Lin-Feng Chen |
Associate Professor of Biochemistry |
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Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. NF-κB signaling and H. pylori-mediated gastric disease. Function of RUNX3 as a tumor suppressor in cancer. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
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| [+][^] | John E Cronan |
Professor and Head of Microbiology |
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Research Statement: Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid Research Interests: Bacterial Genetics, Biofuels, Enzymology, Membrane Biology, Microbial Physiology, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
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| [+][^] | Rutilio "Rudy" A Fratti |
Assistant Professor of Biochemistry |
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Research Statement: Membrane Microdomain Assembly and Membrane Fusion Research Interests: Membrane Biology |
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| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
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Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
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| [+][^] | John A Gerlt |
Professor of Biochemistry |
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Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
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| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
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Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
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| [+][^] | Hong Jin |
Assistant Professor of Biochemistry |
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Research Interests: Protein Synthesis, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology Disease Research Topics: Cancer, Drug Discovery |
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| [+][^] | Auinash Kalsotra |
Assistant Professor of Biochemistry |
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Research Statement: Regulation of alternative splicing and polyadenylation during mammalian heart and liver development. Functional consequences of alternative splicing. Use of microRNAs, anti-sense oligonucleotides and morpholinos as RNA therapeutics. Research Interests: Development, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology Disease Research Topics: Heart Disease, Stroke, and Thrombosis |
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| [+][^] | David M Kranz |
Professor of Biochemistry |
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Research Statement: Structure, Function, and Engineering of T Cell Receptors; Molecular Basis of Immune Recognition by T Cells; Tumor Targeting with T Cells; Engineering Protein Therapeutics Research Interests: Molecular Immunology, Protein Dynamics, Protein Structure, Receptor Biochemistry, Toxins Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
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| [+][^] | Susan A Martinis |
Professor and Head of Biochemistry |
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Research Statement: RNA structure and function, RNA-protein interactions,| chemical mechanisms of biological reactions, protein synthesis, tRNA synthetases Research Interests: Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
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| [+][^] | David S. McPheeters |
Visiting Lecturer and Course Coordinator in Medical Biochemistry, College of Medicine |
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Research Interests: RNA Biology |
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| [+][^] | James "Jim" H. Morrissey |
Professor of Biochemistry |
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Research Statement: Protein-phospholipid interactions; regulation of protease cascades; blood clotting; polyphosphate Research Interests: Enzymology, Membrane Biology, Protein Structure Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Trauma, Bleeding & Tissue Regeneration |
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| [+][^] | Satish K Nair |
Professor of Biochemistry |
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Research Statement: Natural products biosynthesis, bacterial signalling, X-ray crystallography Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
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| [+][^] | Mary A Schuler |
Professor of Cell and Developmental Biology |
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Research Statement: Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases Research Interests: Drug Discovery, Enzymology, Genomics, Protein Structure, Regulation of Gene Expression, RNA Biology |
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| [+][^] | David J Shapiro |
Professor of Biochemistry |
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Research Statement: Identification and use of novel small molecule biomodulators to identify and analyze pathways important in cancer and development of these small molecules as potential anticancer drugs. Research Interests: Chromatin Structure, Drug Discovery, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer |
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| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
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Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
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| [+][^] | Emad Tajkhorshid |
Associate Professor of Biochemistry |
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Research Statement: Computational Studies of Membranes and Membrane Associated Phenomena Research Interests: Computational Biology, Ion Channels, Membrane Biology, Protein Dynamics, Protein Structure |
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| [+][^] | Colin A Wraight |
Professor of Biochemistry |
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Research Statement: Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions Research Interests: Bioenergetics and Photosynthesis, Enzymology, Membrane Biology, Protein Dynamics, Protein Structure |
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Affiliate Faculty of Biochemistry
| [+][^] | Martin D Burke |
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Research Statement: Iterative Cross-Coupling (ICC): Towards a General Strategy for Complex Small Molecule Synthesis; Towards the Total Synthesis of Amphotericin B via Iterative Cross-Coupling; Harnessing the Power of Synthesis to Probe the Structure and Function of the Amphotericin B Ion Channel |
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| [+][^] | Aditi Das |
Assistant Professor, Comparative Biosciences |
| [+][^] | Taekjip Ha |
Professor of Physics |
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Research Statement: Developing and using single-molecule fluorescence microscopy and nano-mechanical manipulation tools for molecular biophysics research |
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| [+][^] | Paul J Hergenrother |
Professor of Chemistry |
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Research Statement: Using small molecules to identify novel targets for the treatment of cancer, drug-resistant bacteria, and neurodegeneration Research Interests: Drug Discovery, RNA Biology Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
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| [+][^] | Deborah E Leckband |
Professor of Chemical Engineering and Bioengineering |
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Research Statement: Molecular Mechanisms of Cell Adhesion; Cell Engineering |
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| [+][^] | Yi Lu |
Professor of Chemistry |
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Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
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| [+][^] | William W Mantulin |
Adjunct Professor of Biochemistry |
| [+][^] | Chad M Rienstra |
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Research Statement: Solid state nuclear magnetic resonance (SSNMR), including the development of new pulse sequence methodology and instrumentation, and application to studies of protein structure and dynamics |
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| [+][^] | Scott K Silverman |
Professor of Chemistry |
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Research Statement: DNA as an enzyme Research Interests: DNA Biology, Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
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| [+][^] | Wilfred A van der Donk |
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Research Statement: The understanding of enzymatic transformations that are of pharmaceutical importance Research Interests: Drug Discovery, Enzymology, Molecular Evolution |
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| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
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Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
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Emeritus Faculty of Biochemistry
| [+][^] | Edward Conrad |
Professor Emeritus of Biochemistry |
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Research Statement: Structure, metabolism, and biological activities of heparin and heparan sulfate |
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| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
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Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
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| [+][^] | Michael Glaser |
Professor Emeritus of Biochemistry |
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Research Statement: Growth factor and hormone regulation of myelin synthesis; membrane domains and signal transduction |
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| [+][^] | Govindjee |
Professor Emeritus of Biochemistry |
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Research Statement: Oxygenic photosynthesis, history of photosynthesis research, and photosynthesis education |
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| [+][^] | Lowell P Hager |
Professor Emeritus of Biochemistry |
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Research Statement: Oxidative enzyme mechanisms and protein chemistry |
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| [+][^] | Eric Jakobsson |
Professor Emeritus of Biochemistry |
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Research Statement: Computational studies of biological transport: understanding and engineering life at the interface |
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| [+][^] | George W Ordal |
Professor Emeritus of Biochemistry |
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Research Statement: Investigation of the molecular basis of excitation and adaptation during chemotactic sensory transduction in bacteria |
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| [+][^] | Robert L Switzer |
Professor Emeritus of Biochemistry |
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Research Statement: Regulation of bacterial gene expression by transcriptional attenuation |
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