Faculty Research Interests
Archaea . Bacterial Genetics . Bioenergetics and Photosynthesis . Biofuels
Bioinformatics . Cell-Matrix Interactions . Chromatin Structure
Computational Biology . Cytoskeleton . Development . DNA Biology . Drug Discovery
Endocrinology . Enzymology . Genomics . Glycobiology . Host-Pathogen Interactions
Imaging . Ion Channels . Learning and Memory . Membrane Biology . Metabolic Regulation
Microbial Ecology . Microbial Physiology . Molecular Evolution
Molecular Immunology . Neurobiology . Pattern Formation . Protein Dynamics
Protein Structure . Protein-Nucleic Acid Interactions . Proteomics
Receptor Biochemistry . Regulation of Gene Expression . Reproductive Biology
RNA Biology . Sensory Processing . Signal Transduction . Toxins . Virology
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Archaea
| [+][^] | Isaac K O Cann |
Professor of Microbiology and Animal Sciences |
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Research Statement: Molecular biology and biochemistry of archaeal DNA replication; enzymes of plant cell wall hydrolysis Research Interests: Archaea, Biofuels, Genomics, Protein-Nucleic Acid Interactions |
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| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
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Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
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| [+][^] | William W Metcalf |
Professor of Microbiology |
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Research Statement: Molecular genetics and biochemistry of methanogenic Archaea; biosynthesis of phosphonate antibiotics; redox cycling of phosphorus by microorganisms Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Drug Discovery, Genomics, Regulation of Gene Expression |
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| [+][^] | Charles G Miller |
Professor of Microbiology |
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Research Statement: Mechanisms of intracellular protein breakdown and proteolytic modification; structure/function relationships in peptide hydrolyzing enzymes Research Interests: Archaea, Bacterial Genetics, Microbial Physiology, Regulation of Gene Expression Disease Research Topics: Heart Disease, Stroke, and Thrombosis |
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| [+][^] | Satish K Nair |
Associate Professor of Biochemistry |
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Research Statement: X-ray crystallography, gene regulation, DNA-protein interactions Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
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| [+][^] | Gary J Olsen |
Professor of Microbiology |
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Research Statement: The functions, evolutionary histories and structures of genes and proteins Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Molecular Evolution |
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| [+][^] | Rachel J Whitaker |
Assistant Professor of Microbiology |
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Research Statement: Microbial ecology and evolution Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Microbial Ecology, Molecular Evolution |
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| [+][^] | Carl R Woese |
Professor of Microbiology |
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Research Statement: Molecular evolution of prokaryotes; structure-function of protein translation apparatus Research Interests: Archaea, Genomics, Molecular Evolution |
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| [+][^] | Ralph S Wolfe |
Professor of Microbiology, Emeritus |
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Research Statement: Biochemistry of methanogens Research Interests: Archaea, Enzymology, Microbial Physiology |
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Bacterial Genetics
| [+][^] | Steven R Blanke |
Professor of Microbiology |
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Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
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| [+][^] | John E Cronan |
Professor and Head of Microbiology |
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Research Statement: Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid Research Interests: Bacterial Genetics, Biofuels, Enzymology, Membrane Biology, Microbial Physiology, Regulation of Gene Expression |
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| [+][^] | Stephen K Farrand |
Professor of Microbiology |
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Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
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| [+][^] | Jeffrey F Gardner |
Professor of Microbiology |
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Research Statement: Mechanism of site-specific recombination by bacteriophages and conjugative transposons; mechanisms of protein recognition of DNA Research Interests: Bacterial Genetics, Protein-Nucleic Acid Interactions |
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| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
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Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
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| [+][^] | Andrei Kuzminov |
Associate Professor of Microbiology |
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Research Statement: Mechanisms of DNA replication stress and genome instability Research Interests: Bacterial Genetics, DNA Biology, Genomics, Host-Pathogen Interactions, Microbial Physiology |
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| [+][^] | William W Metcalf |
Professor of Microbiology |
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Research Statement: Molecular genetics and biochemistry of methanogenic Archaea; biosynthesis of phosphonate antibiotics; redox cycling of phosphorus by microorganisms Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Drug Discovery, Genomics, Regulation of Gene Expression |
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| [+][^] | Charles G Miller |
Professor of Microbiology |
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Research Statement: Mechanisms of intracellular protein breakdown and proteolytic modification; structure/function relationships in peptide hydrolyzing enzymes Research Interests: Archaea, Bacterial Genetics, Microbial Physiology, Regulation of Gene Expression Disease Research Topics: Heart Disease, Stroke, and Thrombosis |
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| [+][^] | Abigail A Salyers |
Professor of Microbiology |
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Research Statement: Antibiotic-resistance gene transfer; interaction of colonic bacteria with host; genetics of obligate anaerobes; conjugative transposons of Bacteroides Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Ecology, Microbial Physiology, Regulation of Gene Expression, RNA Biology |
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| [+][^] | James M Slauch |
Professor of Microbiology |
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Research Statement: Molecular mechanisms of Salmonella pathogenesis Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
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| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
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Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
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Bioenergetics and Photosynthesis
| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
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Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
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| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
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Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
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| [+][^] | Yi Lu |
Professor of Chemistry |
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Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
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| [+][^] | William W Metcalf |
Professor of Microbiology |
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Research Statement: Molecular genetics and biochemistry of methanogenic Archaea; biosynthesis of phosphonate antibiotics; redox cycling of phosphorus by microorganisms Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Drug Discovery, Genomics, Regulation of Gene Expression |
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| [+][^] | Colin A Wraight |
Professor of Biochemistry |
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Research Statement: Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions Research Interests: Bioenergetics and Photosynthesis, Enzymology, Membrane Biology, Protein Dynamics, Protein Structure |
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Biofuels
| [+][^] | Isaac K O Cann |
Professor of Microbiology and Animal Sciences |
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Research Statement: Molecular biology and biochemistry of archaeal DNA replication; enzymes of plant cell wall hydrolysis Research Interests: Archaea, Biofuels, Genomics, Protein-Nucleic Acid Interactions |
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| [+][^] | John E Cronan |
Professor and Head of Microbiology |
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Research Statement: Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid Research Interests: Bacterial Genetics, Biofuels, Enzymology, Membrane Biology, Microbial Physiology, Regulation of Gene Expression |
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| [+][^] | John A Gerlt |
Professor of Biochemistry |
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Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
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| [+][^] | Yi Lu |
Professor of Chemistry |
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Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
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| [+][^] | Satish K Nair |
Associate Professor of Biochemistry |
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Research Statement: X-ray crystallography, gene regulation, DNA-protein interactions Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
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| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
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Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
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Bioinformatics
| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
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Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
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| [+][^] | John A Gerlt |
Professor of Biochemistry |
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Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
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| [+][^] | Yi Lu |
Professor of Chemistry |
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Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
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| [+][^] | Douglas A. Mitchell |
Assistant Professor of Chemistry |
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Research Statement: Molecular underpinnings of bacterial virulence Research Interests: Bioinformatics, Drug Discovery, Enzymology, Host-Pathogen Interactions, Toxins |
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| [+][^] | Gary J Olsen |
Professor of Microbiology |
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Research Statement: The functions, evolutionary histories and structures of genes and proteins Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Molecular Evolution |
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| [+][^] | Hugh M Robertson |
Professor of Entomology |
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Research Statement: Molecular basis of insect olfaction; molecular evolution of DNA transposons; comparative insect genomics; molecular evolution of nematode chemoreceptors Research Interests: Bioinformatics, Genomics, Molecular Evolution |
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| [+][^] | Lisa J Stubbs |
Professor of Cell and Developmental Biology |
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Research Statement: Evolution of gene regulatory networks; Long-range regulatory mechanisms; Mouse models for human disease Research Interests: Bioinformatics, Chromatin Structure, Development, Genomics, Molecular Evolution, Regulation of Gene Expression |
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| [+][^] | Rachel J Whitaker |
Assistant Professor of Microbiology |
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Research Statement: Microbial ecology and evolution Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Microbial Ecology, Molecular Evolution |
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| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
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Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
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Cell-Matrix Interactions
| [+][^] | Stephen J Kaufman |
Professor of Cell and Developmental Biology, Emeritus |
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Research Statement: Role of integrins and extracellular matrix proteins in skeletal muscle development, formation of the neuromuscular junction, and muscular dystrophy Research Interests: Cell-Matrix Interactions, Membrane Biology, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction |
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| [+][^] | Fei Wang |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Human pluripotent stem cells; neutrophil polarity and chemotaxis Research Interests: Cell-Matrix Interactions, Cytoskeleton, Development, Imaging, Signal Transduction Disease Research Topics: Drug Discovery |
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| [+][^] | Benjamin D Williams |
Associate Professor of Cell and Developmental Biology |
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Research Statement: Software for Medical Education Research Interests: Cell-Matrix Interactions, Regulation of Gene Expression |
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Chromatin Structure
| [+][^] | Andrew S Belmont |
Professor of Cell and Developmental Biology |
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Research Statement: Chromatin Structure, Gene expression, Nuclear Architecture Research Interests: Chromatin Structure, Imaging, Regulation of Gene Expression |
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| [+][^] | Lin-Feng Chen |
Assistant Professor of Biochemistry |
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Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
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| [+][^] | Jongsook Kim Kemper |
Associate Professor of Molecular and Integrative Physiology |
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Research Statement: Nuclear Receptor Action in Metabolic Regulation: Applications to Metabolic Disorders including Fatty liver, Obesity, and Diabetes Research Interests: Chromatin Structure, Endocrinology, Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes |
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| [+][^] | Craig Mizzen |
Associate Professor of Cell and Developmental Biology |
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Research Statement: Chromatin structure, function and metabolism. Roles of histone modifications and other epigenetic factors in normal development and disease. Research Interests: Chromatin Structure, Protein-Nucleic Acid Interactions, Regulation of Gene Expression Disease Research Topics: Cancer |
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| [+][^] | Ann M Nardulli |
Professor of Molecular and Integrative Physiology |
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Research Statement: Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection Research Interests: Chromatin Structure, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer |
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| [+][^] | Supriya Prasanth |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Eukaryotic DNA replication; Chromosome structure & maintenance; Heterochromatin organization; Cell cycle control Research Interests: Chromatin Structure, Protein-Nucleic Acid Interactions |
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| [+][^] | Lisa J Stubbs |
Professor of Cell and Developmental Biology |
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Research Statement: Evolution of gene regulatory networks; Long-range regulatory mechanisms; Mouse models for human disease Research Interests: Bioinformatics, Chromatin Structure, Development, Genomics, Molecular Evolution, Regulation of Gene Expression |
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Computational Biology
| [+][^] | Thomas J Anastasio |
Associate Professor of Molecular and Integrative Physiology |
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Research Statement: Multilevel modeling of neurobiological systems in health and disease. Research Interests: Computational Biology, Neurobiology Disease Research Topics: Neurological and Behavioral Disorders |
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| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
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Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
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| [+][^] | Rhanor Gillette |
Professor of Molecular and Integrative Physiology |
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Research Statement: Neural Bases of Decision Research Interests: Computational Biology, Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
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| [+][^] | Daniel Llano |
Assistant Professor in Molecular and Integrative Physiology and the College of Medicine |
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Research Statement: The role of top-down projections in the processing of complex sounds Research Interests: Computational Biology, Imaging, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
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| [+][^] | Jay E Mittenthal |
Associate Professor of Cell and Developmental Biology, Emeritus |
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Research Statement: Computational biology: Design and evolution of molecular networks Research Interests: Computational Biology |
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| [+][^] | Mark E Nelson |
Professor of Molecular and Integrative Physiology |
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Research Statement: Computational Neuroscience; Neuroethology; Adaptive Behaviour Research Interests: Computational Biology, Learning and Memory, Neurobiology, Sensory Processing |
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| [+][^] | M Ashley Spies |
Research Assistant Professor of Biochemistry |
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Research Statement: Computer-aided Drug Discovery (CADD); Computational Chemistry: QC/MM applied to Enzyme Catalysis; Virtual Screening; kinetic isotope effects; kinetics; origins of enzyme catalytic power; bioorganic chemistry; amino acid racemases and epimerases; pyridoxal-5'-phosphate (PLP) chemistry and enzymology Research Interests: Computational Biology, Drug Discovery, Enzymology, Protein Dynamics Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
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| [+][^] | Emad Tajkhorshid |
Associate Professor of Biochemistry |
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Research Statement: Computational Studies of Membranes and Membrane Associated Phenomena Research Interests: Computational Biology, Ion Channels, Membrane Biology, Protein Dynamics, Protein Structure |
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Cytoskeleton
| [+][^] | William M Brieher |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Cytoskeleton Cell adhesion Research Interests: Cytoskeleton |
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| [+][^] | Martha U Gillette |
Alumni Professor of Cell and Developmental Biology |
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Research Statement: The neurobiology of time; engineering neuronal development and repair Research Interests: Cytoskeleton, Development, Neurobiology, Proteomics, Signal Transduction Disease Research Topics: Neurological and Behavioral Disorders |
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| [+][^] | Fei Wang |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Human pluripotent stem cells; neutrophil polarity and chemotaxis Research Interests: Cell-Matrix Interactions, Cytoskeleton, Development, Imaging, Signal Transduction Disease Research Topics: Drug Discovery |
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Development
| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
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Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
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| [+][^] | Jo Ann Cameron |
Professor Emerita of Cell and Developmental Biology |
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Research Statement: Cellular and molecular mechanisms that control amphibian limb regeneration Research Interests: Development, Pattern Formation |
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| [+][^] | Jie Chen |
Professor of Cell and Developmental Biology |
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Research Statement: Nutrient-sensing signal transduction in mammalian cell growth, differentiation, and metabolism Research Interests: Development, Endocrinology, Signal Transduction Disease Research Topics: Cancer, Metabolic Disorders/Diabetes, Trauma, Bleeding & Tissue Regeneration |
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| [+][^] | Martha U Gillette |
Alumni Professor of Cell and Developmental Biology |
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Research Statement: The neurobiology of time; engineering neuronal development and repair Research Interests: Cytoskeleton, Development, Neurobiology, Proteomics, Signal Transduction Disease Research Topics: Neurological and Behavioral Disorders |
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| [+][^] | William Greenough |
Professor Emeritus of Molecular and Integrative Physiology |
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Research Statement: Brain plasticity in learning and memory; cellular signalling in brain plasticity; mechanisms of brain development; role of experience in brain maturation Research Interests: Development, Learning and Memory, Neurobiology |
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| [+][^] | Esmail "Essie" Meisami |
Associate Professor of Molecular and Integrative Physiology |
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Research Statement: Brain development; hormones & growth factors in recovery from early neural retardation; neurobiology of the olfactory system Research Interests: Development, Neurobiology, Sensory Processing |
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| [+][^] | Phillip A Newmark |
Associate Professor of Cell and Developmental Biology |
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Research Statement: Planarian regeneration, germ cell development, schistosomes Research Interests: Development, Pattern Formation, Reproductive Biology Disease Research Topics: Infectious Diseases, Reproductive Diseases and Infertility |
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| [+][^] | Lori T Raetzman |
Assistant Professor of Molecular and Integrative Physiology |
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Research Statement: Notch signaling pathway in pituitary gland development and disease Research Interests: Development, Endocrinology, Signal Transduction Disease Research Topics: Cancer |
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| [+][^] | Gene E Robinson |
Swanlund Chair and Center for Advanced Study Professor |
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Research Statement: From society to genes Research Interests: Development |
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| [+][^] | Rachel Smith-Bolton |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Wound repair and tissue regeneration; Drosophila genetics; Development and patterning Research Interests: Development, Pattern Formation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Trauma, Bleeding & Tissue Regeneration |
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| [+][^] | Lisa J Stubbs |
Professor of Cell and Developmental Biology |
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Research Statement: Evolution of gene regulatory networks; Long-range regulatory mechanisms; Mouse models for human disease Research Interests: Bioinformatics, Chromatin Structure, Development, Genomics, Molecular Evolution, Regulation of Gene Expression |
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| [+][^] | Fei Wang |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Human pluripotent stem cells; neutrophil polarity and chemotaxis Research Interests: Cell-Matrix Interactions, Cytoskeleton, Development, Imaging, Signal Transduction Disease Research Topics: Drug Discovery |
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DNA Biology
| [+][^] | Andrei Kuzminov |
Associate Professor of Microbiology |
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Research Statement: Mechanisms of DNA replication stress and genome instability Research Interests: Bacterial Genetics, DNA Biology, Genomics, Host-Pathogen Interactions, Microbial Physiology |
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| [+][^] | Yi Lu |
Professor of Chemistry |
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Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
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| [+][^] | Scott K Silverman |
Professor of Chemistry |
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Research Statement: DNA as an enzyme Research Interests: DNA Biology, Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
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| [+][^] | Maria Spies |
Assistant Professor of Biochemistry |
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Research Statement: Molecular mechanisms of DNA helicases and DNA motor proteins; mechanistic aspects of protein-nucleic acids and protein-protein interactions; homologous genetic recombination; DNA repair; molecular motors Research Interests: DNA Biology, Protein-Nucleic Acid Interactions Disease Research Topics: Cancer |
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Drug Discovery
| [+][^] | Paul J Hergenrother |
Professor of Chemistry |
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Research Statement: Using small molecules to identify novel targets for the treatment of cancer, drug-resistant bacteria, and neurodegeneration Research Interests: Drug Discovery, RNA Biology Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
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| [+][^] | William W Metcalf |
Professor of Microbiology |
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Research Statement: Molecular genetics and biochemistry of methanogenic Archaea; biosynthesis of phosphonate antibiotics; redox cycling of phosphorus by microorganisms Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Drug Discovery, Genomics, Regulation of Gene Expression |
||
| [+][^] | Douglas A. Mitchell |
Assistant Professor of Chemistry |
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Research Statement: Molecular underpinnings of bacterial virulence Research Interests: Bioinformatics, Drug Discovery, Enzymology, Host-Pathogen Interactions, Toxins |
||
| [+][^] | Satish K Nair |
Associate Professor of Biochemistry |
|
Research Statement: X-ray crystallography, gene regulation, DNA-protein interactions Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
||
| [+][^] | Mary A Schuler |
Professor of Cell and Developmental Biology |
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Research Statement: Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases Research Interests: Drug Discovery, Enzymology, Genomics, Protein Structure, Regulation of Gene Expression, RNA Biology |
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| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
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Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | M Ashley Spies |
Research Assistant Professor of Biochemistry |
|
Research Statement: Computer-aided Drug Discovery (CADD); Computational Chemistry: QC/MM applied to Enzyme Catalysis; Virtual Screening; kinetic isotope effects; kinetics; origins of enzyme catalytic power; bioorganic chemistry; amino acid racemases and epimerases; pyridoxal-5'-phosphate (PLP) chemistry and enzymology Research Interests: Computational Biology, Drug Discovery, Enzymology, Protein Dynamics Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
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| [+][^] | Wilfred A van der Donk |
Affiliate, Department of Biochemistry |
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Research Statement: The understanding of enzymatic transformations that are of pharmaceutical importance Research Interests: Drug Discovery, Enzymology, Molecular Evolution |
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| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
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Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
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Endocrinology
| [+][^] | Milan K Bagchi |
Professor of Molecular and Integrative Physiology |
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Research Statement: Mechanisms of Steroid Hormone Signaling in Reproduction and Development Breast Cancer Research Interests: Endocrinology, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
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| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Jie Chen |
Professor of Cell and Developmental Biology |
|
Research Statement: Nutrient-sensing signal transduction in mammalian cell growth, differentiation, and metabolism Research Interests: Development, Endocrinology, Signal Transduction Disease Research Topics: Cancer, Metabolic Disorders/Diabetes, Trauma, Bleeding & Tissue Regeneration |
||
| [+][^] | Lin-Feng Chen |
Assistant Professor of Biochemistry |
|
Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Benita S Katzenellenbogen |
Swanlund Professor of Molecular and Integrative Physiology |
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Research Statement: Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors and their genome-wide activities Research Interests: Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Jongsook Kim Kemper |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Nuclear Receptor Action in Metabolic Regulation: Applications to Metabolic Disorders including Fatty liver, Obesity, and Diabetes Research Interests: Chromatin Structure, Endocrinology, Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes |
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| [+][^] | Ann M Nardulli |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection Research Interests: Chromatin Structure, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Lori T Raetzman |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Notch signaling pathway in pituitary gland development and disease Research Interests: Development, Endocrinology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Victor D Ramirez |
Professor Emeritus of Molecular and Integrative Physiology |
|
Research Statement: Molecular Neuroendocrinology Research Interests: Endocrinology, Neurobiology, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
|
Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
Enzymology
| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
|
Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
||
| [+][^] | John E Cronan |
Professor and Head of Microbiology |
|
Research Statement: Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid Research Interests: Bacterial Genetics, Biofuels, Enzymology, Membrane Biology, Microbial Physiology, Regulation of Gene Expression |
||
| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
|
Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
||
| [+][^] | John A Gerlt |
Professor of Biochemistry |
|
Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
||
| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
|
Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
||
| [+][^] | James A Imlay |
Professor of Microbiology |
|
Research Statement: Molecular mechanisms of oxidative damage; cellular defenses against oxidants; obligate anaerobiosis Research Interests: Enzymology, Microbial Physiology |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | Susan A Martinis |
Professor and Head of Biochemistry |
|
Research Statement: RNA structure and function, RNA-protein interactions,| chemical mechanisms of biological reactions, protein synthesis, tRNA synthetases Research Interests: Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | Douglas A. Mitchell |
Assistant Professor of Chemistry |
|
Research Statement: Molecular underpinnings of bacterial virulence Research Interests: Bioinformatics, Drug Discovery, Enzymology, Host-Pathogen Interactions, Toxins |
||
| [+][^] | James H. Morrissey |
Professor of Biochemistry |
|
Research Statement: Protein-phospholipid interactions; regulation of protease cascades; blood clotting; polyphosphate Research Interests: Enzymology, Membrane Biology, Protein Structure Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Trauma, Bleeding & Tissue Regeneration |
||
| [+][^] | Satish K Nair |
Associate Professor of Biochemistry |
|
Research Statement: X-ray crystallography, gene regulation, DNA-protein interactions Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
||
| [+][^] | Peter A B Orlean |
Professor of Microbiology |
|
Research Statement: Biogenesis of cell surface glycans in yeast and pathogenic fungi Research Interests: Enzymology, Glycobiology, Membrane Biology, Microbial Physiology |
||
| [+][^] | Mary A Schuler |
Professor of Cell and Developmental Biology |
|
Research Statement: Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases Research Interests: Drug Discovery, Enzymology, Genomics, Protein Structure, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Scott K Silverman |
Professor of Chemistry |
|
Research Statement: DNA as an enzyme Research Interests: DNA Biology, Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
|
Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | M Ashley Spies |
Research Assistant Professor of Biochemistry |
|
Research Statement: Computer-aided Drug Discovery (CADD); Computational Chemistry: QC/MM applied to Enzyme Catalysis; Virtual Screening; kinetic isotope effects; kinetics; origins of enzyme catalytic power; bioorganic chemistry; amino acid racemases and epimerases; pyridoxal-5'-phosphate (PLP) chemistry and enzymology Research Interests: Computational Biology, Drug Discovery, Enzymology, Protein Dynamics Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
||
| [+][^] | Wilfred A van der Donk |
Affiliate, Department of Biochemistry |
|
Research Statement: The understanding of enzymatic transformations that are of pharmaceutical importance Research Interests: Drug Discovery, Enzymology, Molecular Evolution |
||
| [+][^] | Ralph S Wolfe |
Professor of Microbiology, Emeritus |
|
Research Statement: Biochemistry of methanogens Research Interests: Archaea, Enzymology, Microbial Physiology |
||
| [+][^] | Colin A Wraight |
Professor of Biochemistry |
|
Research Statement: Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions Research Interests: Bioenergetics and Photosynthesis, Enzymology, Membrane Biology, Protein Dynamics, Protein Structure |
||
| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
|
Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
||
Genomics
| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Isaac K O Cann |
Professor of Microbiology and Animal Sciences |
|
Research Statement: Molecular biology and biochemistry of archaeal DNA replication; enzymes of plant cell wall hydrolysis Research Interests: Archaea, Biofuels, Genomics, Protein-Nucleic Acid Interactions |
||
| [+][^] | David F Clayton |
Professor of Cell and Developmental Biology |
|
Research Statement: Neurogenomics; cellular mechanisms of neural plasticity; songbird model system Research Interests: Genomics, Learning and Memory, Neurobiology |
||
| [+][^] | Brian C Freeman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Hsp90 Chaperone System Chromatin Landmarks Gene Regulation Telomere Biology Research Interests: Genomics, Protein Dynamics, Protein-Nucleic Acid Interactions, Proteomics, Regulation of Gene Expression Disease Research Topics: Cancer |
||
| [+][^] | John A Gerlt |
Professor of Biochemistry |
|
Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
||
| [+][^] | Benita S Katzenellenbogen |
Swanlund Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors and their genome-wide activities Research Interests: Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Jongsook Kim Kemper |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Nuclear Receptor Action in Metabolic Regulation: Applications to Metabolic Disorders including Fatty liver, Obesity, and Diabetes Research Interests: Chromatin Structure, Endocrinology, Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes |
||
| [+][^] | Andrei Kuzminov |
Associate Professor of Microbiology |
|
Research Statement: Mechanisms of DNA replication stress and genome instability Research Interests: Bacterial Genetics, DNA Biology, Genomics, Host-Pathogen Interactions, Microbial Physiology |
||
| [+][^] | Kurt E Kwast |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Oxygen sensing, transcriptional regulation of oxygen-responsive genes, physiological genomics of oxygen regulation. Research Interests: Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | William W Metcalf |
Professor of Microbiology |
|
Research Statement: Molecular genetics and biochemistry of methanogenic Archaea; biosynthesis of phosphonate antibiotics; redox cycling of phosphorus by microorganisms Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Drug Discovery, Genomics, Regulation of Gene Expression |
||
| [+][^] | Gary J Olsen |
Professor of Microbiology |
|
Research Statement: The functions, evolutionary histories and structures of genes and proteins Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Molecular Evolution |
||
| [+][^] | Hugh M Robertson |
Professor of Entomology |
|
Research Statement: Molecular basis of insect olfaction; molecular evolution of DNA transposons; comparative insect genomics; molecular evolution of nematode chemoreceptors Research Interests: Bioinformatics, Genomics, Molecular Evolution |
||
| [+][^] | Mary A Schuler |
Professor of Cell and Developmental Biology |
|
Research Statement: Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases Research Interests: Drug Discovery, Enzymology, Genomics, Protein Structure, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Lisa J Stubbs |
Professor of Cell and Developmental Biology |
|
Research Statement: Evolution of gene regulatory networks; Long-range regulatory mechanisms; Mouse models for human disease Research Interests: Bioinformatics, Chromatin Structure, Development, Genomics, Molecular Evolution, Regulation of Gene Expression |
||
| [+][^] | Richard I Tapping |
Associate Professor of Microbiology |
|
Research Statement: The Role of Toll-like Receptors in Host Innate Immune Defense. The genetic basis of host resistance to Yersinia pestis infection. Research Interests: Genomics, Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry Disease Research Topics: Infectious Diseases |
||
| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
|
Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
||
| [+][^] | Rachel J Whitaker |
Assistant Professor of Microbiology |
|
Research Statement: Microbial ecology and evolution Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Microbial Ecology, Molecular Evolution |
||
| [+][^] | Carl R Woese |
Professor of Microbiology |
|
Research Statement: Molecular evolution of prokaryotes; structure-function of protein translation apparatus Research Interests: Archaea, Genomics, Molecular Evolution |
||
Glycobiology
| [+][^] | Peter A B Orlean |
Professor of Microbiology |
|
Research Statement: Biogenesis of cell surface glycans in yeast and pathogenic fungi Research Interests: Enzymology, Glycobiology, Membrane Biology, Microbial Physiology |
||
Host-Pathogen Interactions
| [+][^] | Steven R Blanke |
Professor of Microbiology |
|
Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Lin-Feng Chen |
Assistant Professor of Biochemistry |
|
Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Stephen K Farrand |
Professor of Microbiology |
|
Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
||
| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
|
Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
||
| [+][^] | Andrei Kuzminov |
Associate Professor of Microbiology |
|
Research Statement: Mechanisms of DNA replication stress and genome instability Research Interests: Bacterial Genetics, DNA Biology, Genomics, Host-Pathogen Interactions, Microbial Physiology |
||
| [+][^] | Douglas A. Mitchell |
Assistant Professor of Chemistry |
|
Research Statement: Molecular underpinnings of bacterial virulence Research Interests: Bioinformatics, Drug Discovery, Enzymology, Host-Pathogen Interactions, Toxins |
||
| [+][^] | Gary J Olsen |
Professor of Microbiology |
|
Research Statement: The functions, evolutionary histories and structures of genes and proteins Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Molecular Evolution |
||
| [+][^] | Abigail A Salyers |
Professor of Microbiology |
|
Research Statement: Antibiotic-resistance gene transfer; interaction of colonic bacteria with host; genetics of obligate anaerobes; conjugative transposons of Bacteroides Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Ecology, Microbial Physiology, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Joanna L. Shisler |
Associate Professor of Microbiology |
|
Research Statement: Immune evasion strategies of viruses; viral mechanisms to inhibit inflammation; host-pathogen interactions Research Interests: Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Virology Disease Research Topics: Infectious Diseases |
||
| [+][^] | James M Slauch |
Professor of Microbiology |
|
Research Statement: Molecular mechanisms of Salmonella pathogenesis Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
||
| [+][^] | Richard I Tapping |
Associate Professor of Microbiology |
|
Research Statement: The Role of Toll-like Receptors in Host Innate Immune Defense. The genetic basis of host resistance to Yersinia pestis infection. Research Interests: Genomics, Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry Disease Research Topics: Infectious Diseases |
||
| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
|
Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
||
| [+][^] | Rachel J Whitaker |
Assistant Professor of Microbiology |
|
Research Statement: Microbial ecology and evolution Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Microbial Ecology, Molecular Evolution |
||
| [+][^] | Brenda Anne Wilson |
Associate Professor of Microbiology |
|
Research Statement: Bacterial protein toxins, their interaction with host cells, their effects on intracellular signal transduction, and development of novel alternative anti-toxin therapeutics; human and nonhuman primate vaginal microbial ecosystems and their role in health and disease Research Interests: Host-Pathogen Interactions, Microbial Ecology, Signal Transduction, Toxins Disease Research Topics: Drug Discovery, Infectious Diseases, Neurological and Behavioral Disorders, Reproductive Diseases and Infertility |
||
Imaging
| [+][^] | Andrew S Belmont |
Professor of Cell and Developmental Biology |
|
Research Statement: Chromatin Structure, Gene expression, Nuclear Architecture Research Interests: Chromatin Structure, Imaging, Regulation of Gene Expression |
||
| [+][^] | Charles "Lee" Cox |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Functional organization and neuromodulation of thalamocortical circuits, Neuronal excitability, Synaptic Physiology and Plasticity. Fragile X Syndrome, Epilepsy, Alzheimer's Disease Research Interests: Imaging, Ion Channels, Learning and Memory, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Daniel Llano |
Assistant Professor in Molecular and Integrative Physiology and the College of Medicine |
|
Research Statement: The role of top-down projections in the processing of complex sounds Research Interests: Computational Biology, Imaging, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | Fei Wang |
Assistant Professor of Cell and Developmental Biology |
|
Research Statement: Human pluripotent stem cells; neutrophil polarity and chemotaxis Research Interests: Cell-Matrix Interactions, Cytoskeleton, Development, Imaging, Signal Transduction Disease Research Topics: Drug Discovery |
||
Ion Channels
| [+][^] | Philip M Best |
Associate Dean, College of LAS |
|
Research Statement: Calcium channels in the heart: structure, function and regulation Research Interests: Ion Channels, Signal Transduction |
||
| [+][^] | Hee Jung Chung |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Activity-dependent regulation of ion channels in Synaptic and Intrinsic Plasticity Research Interests: Ion Channels, Learning and Memory, Neurobiology Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Charles "Lee" Cox |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Functional organization and neuromodulation of thalamocortical circuits, Neuronal excitability, Synaptic Physiology and Plasticity. Fragile X Syndrome, Epilepsy, Alzheimer's Disease Research Interests: Imaging, Ion Channels, Learning and Memory, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
|
Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
||
| [+][^] | Albert S Feng |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural basis of sound pattern recognition Research Interests: Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing |
||
| [+][^] | Rhanor Gillette |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural Bases of Decision Research Interests: Computational Biology, Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Claudio Grosman |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Molecular Mechanisms of Neurotransmitter-gated Ion Channels Research Interests: Ion Channels, Membrane Biology, Neurobiology, Protein Dynamics Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Emad Tajkhorshid |
Associate Professor of Biochemistry |
|
Research Statement: Computational Studies of Membranes and Membrane Associated Phenomena Research Interests: Computational Biology, Ion Channels, Membrane Biology, Protein Dynamics, Protein Structure |
||
Learning and Memory
| [+][^] | Hee Jung Chung |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Activity-dependent regulation of ion channels in Synaptic and Intrinsic Plasticity Research Interests: Ion Channels, Learning and Memory, Neurobiology Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | David F Clayton |
Professor of Cell and Developmental Biology |
|
Research Statement: Neurogenomics; cellular mechanisms of neural plasticity; songbird model system Research Interests: Genomics, Learning and Memory, Neurobiology |
||
| [+][^] | Charles "Lee" Cox |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Functional organization and neuromodulation of thalamocortical circuits, Neuronal excitability, Synaptic Physiology and Plasticity. Fragile X Syndrome, Epilepsy, Alzheimer's Disease Research Interests: Imaging, Ion Channels, Learning and Memory, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Albert S Feng |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural basis of sound pattern recognition Research Interests: Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing |
||
| [+][^] | Rhanor Gillette |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural Bases of Decision Research Interests: Computational Biology, Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | William Greenough |
Professor Emeritus of Molecular and Integrative Physiology |
|
Research Statement: Brain plasticity in learning and memory; cellular signalling in brain plasticity; mechanisms of brain development; role of experience in brain maturation Research Interests: Development, Learning and Memory, Neurobiology |
||
| [+][^] | Mark E Nelson |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Computational Neuroscience; Neuroethology; Adaptive Behaviour Research Interests: Computational Biology, Learning and Memory, Neurobiology, Sensory Processing |
||
| [+][^] | Yang "Kevin" Xiang |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: GPCR signaling in Alzheimer's diseases and heart failure Research Interests: Learning and Memory, Membrane Biology, Receptor Biochemistry, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes, Neurological and Behavioral Disorders |
||
Membrane Biology
| [+][^] | Steven R Blanke |
Professor of Microbiology |
|
Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
|
Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
||
| [+][^] | John E Cronan |
Professor and Head of Microbiology |
|
Research Statement: Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid Research Interests: Bacterial Genetics, Biofuels, Enzymology, Membrane Biology, Microbial Physiology, Regulation of Gene Expression |
||
| [+][^] | Rutilio "Rudy" A Fratti |
Assistant Professor of Biochemistry |
|
Research Statement: Membrane Microdomain Assembly and Membrane Fusion Research Interests: Membrane Biology |
||
| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
|
Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
||
| [+][^] | Julia M George |
Research Associate Professor of Cell and Developmental Biology |
|
Research Statement: Synuclein proteins and neurodegenerative disease Research Interests: Membrane Biology, Neurobiology, Protein Structure Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Claudio Grosman |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Molecular Mechanisms of Neurotransmitter-gated Ion Channels Research Interests: Ion Channels, Membrane Biology, Neurobiology, Protein Dynamics Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Stephen J Kaufman |
Professor of Cell and Developmental Biology, Emeritus |
|
Research Statement: Role of integrins and extracellular matrix proteins in skeletal muscle development, formation of the neuromuscular junction, and muscular dystrophy Research Interests: Cell-Matrix Interactions, Membrane Biology, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | James H. Morrissey |
Professor of Biochemistry |
|
Research Statement: Protein-phospholipid interactions; regulation of protease cascades; blood clotting; polyphosphate Research Interests: Enzymology, Membrane Biology, Protein Structure Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Trauma, Bleeding & Tissue Regeneration |
||
| [+][^] | Satish K Nair |
Associate Professor of Biochemistry |
|
Research Statement: X-ray crystallography, gene regulation, DNA-protein interactions Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
||
| [+][^] | Peter A B Orlean |
Professor of Microbiology |
|
Research Statement: Biogenesis of cell surface glycans in yeast and pathogenic fungi Research Interests: Enzymology, Glycobiology, Membrane Biology, Microbial Physiology |
||
| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
|
Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Emad Tajkhorshid |
Associate Professor of Biochemistry |
|
Research Statement: Computational Studies of Membranes and Membrane Associated Phenomena Research Interests: Computational Biology, Ion Channels, Membrane Biology, Protein Dynamics, Protein Structure |
||
| [+][^] | Colin A Wraight |
Professor of Biochemistry |
|
Research Statement: Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions Research Interests: Bioenergetics and Photosynthesis, Enzymology, Membrane Biology, Protein Dynamics, Protein Structure |
||
| [+][^] | Yang "Kevin" Xiang |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: GPCR signaling in Alzheimer's diseases and heart failure Research Interests: Learning and Memory, Membrane Biology, Receptor Biochemistry, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes, Neurological and Behavioral Disorders |
||
Metabolic Regulation
| [+][^] | Jongsook Kim Kemper |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Nuclear Receptor Action in Metabolic Regulation: Applications to Metabolic Disorders including Fatty liver, Obesity, and Diabetes Research Interests: Chromatin Structure, Endocrinology, Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes |
||
| [+][^] | Kurt E Kwast |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Oxygen sensing, transcriptional regulation of oxygen-responsive genes, physiological genomics of oxygen regulation. Research Interests: Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction |
||
Microbial Ecology
| [+][^] | Bruce W Fouke |
Professor in Geology, Microbiology, and the Institute for Genomic Biology |
|
Research Statement: Does microbial metabolic activity, macromolecular chemistry and extracellular polymeric substance (EPS) production cause disease in coral reef ecosystems and catalyze CaCO3 mineral precipitation in hot springs and caves? Research Interests: Microbial Ecology |
||
| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
|
Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
||
| [+][^] | Abigail A Salyers |
Professor of Microbiology |
|
Research Statement: Antibiotic-resistance gene transfer; interaction of colonic bacteria with host; genetics of obligate anaerobes; conjugative transposons of Bacteroides Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Ecology, Microbial Physiology, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Rachel J Whitaker |
Assistant Professor of Microbiology |
|
Research Statement: Microbial ecology and evolution Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Microbial Ecology, Molecular Evolution |
||
| [+][^] | Brenda Anne Wilson |
Associate Professor of Microbiology |
|
Research Statement: Bacterial protein toxins, their interaction with host cells, their effects on intracellular signal transduction, and development of novel alternative anti-toxin therapeutics; human and nonhuman primate vaginal microbial ecosystems and their role in health and disease Research Interests: Host-Pathogen Interactions, Microbial Ecology, Signal Transduction, Toxins Disease Research Topics: Drug Discovery, Infectious Diseases, Neurological and Behavioral Disorders, Reproductive Diseases and Infertility |
||
Microbial Physiology
| [+][^] | Steven R Blanke |
Professor of Microbiology |
|
Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
|
Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
||
| [+][^] | John E Cronan |
Professor and Head of Microbiology |
|
Research Statement: Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid Research Interests: Bacterial Genetics, Biofuels, Enzymology, Membrane Biology, Microbial Physiology, Regulation of Gene Expression |
||
| [+][^] | Stephen K Farrand |
Professor of Microbiology |
|
Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
||
| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
|
Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
||
| [+][^] | John A Gerlt |
Professor of Biochemistry |
|
Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
||
| [+][^] | James A Imlay |
Professor of Microbiology |
|
Research Statement: Molecular mechanisms of oxidative damage; cellular defenses against oxidants; obligate anaerobiosis Research Interests: Enzymology, Microbial Physiology |
||
| [+][^] | Andrei Kuzminov |
Associate Professor of Microbiology |
|
Research Statement: Mechanisms of DNA replication stress and genome instability Research Interests: Bacterial Genetics, DNA Biology, Genomics, Host-Pathogen Interactions, Microbial Physiology |
||
| [+][^] | Charles G Miller |
Professor of Microbiology |
|
Research Statement: Mechanisms of intracellular protein breakdown and proteolytic modification; structure/function relationships in peptide hydrolyzing enzymes Research Interests: Archaea, Bacterial Genetics, Microbial Physiology, Regulation of Gene Expression Disease Research Topics: Heart Disease, Stroke, and Thrombosis |
||
| [+][^] | Peter A B Orlean |
Professor of Microbiology |
|
Research Statement: Biogenesis of cell surface glycans in yeast and pathogenic fungi Research Interests: Enzymology, Glycobiology, Membrane Biology, Microbial Physiology |
||
| [+][^] | Abigail A Salyers |
Professor of Microbiology |
|
Research Statement: Antibiotic-resistance gene transfer; interaction of colonic bacteria with host; genetics of obligate anaerobes; conjugative transposons of Bacteroides Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Ecology, Microbial Physiology, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
|
Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
||
| [+][^] | Ralph S Wolfe |
Professor of Microbiology, Emeritus |
|
Research Statement: Biochemistry of methanogens Research Interests: Archaea, Enzymology, Microbial Physiology |
||
Molecular Evolution
| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
|
Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
||
| [+][^] | Stephen K Farrand |
Professor of Microbiology |
|
Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
||
| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
|
Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
||
| [+][^] | John A Gerlt |
Professor of Biochemistry |
|
Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
||
| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
|
Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | Susan A Martinis |
Professor and Head of Biochemistry |
|
Research Statement: RNA structure and function, RNA-protein interactions,| chemical mechanisms of biological reactions, protein synthesis, tRNA synthetases Research Interests: Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | Gary J Olsen |
Professor of Microbiology |
|
Research Statement: The functions, evolutionary histories and structures of genes and proteins Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Molecular Evolution |
||
| [+][^] | Hugh M Robertson |
Professor of Entomology |
|
Research Statement: Molecular basis of insect olfaction; molecular evolution of DNA transposons; comparative insect genomics; molecular evolution of nematode chemoreceptors Research Interests: Bioinformatics, Genomics, Molecular Evolution |
||
| [+][^] | Scott K Silverman |
Professor of Chemistry |
|
Research Statement: DNA as an enzyme Research Interests: DNA Biology, Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | Lisa J Stubbs |
Professor of Cell and Developmental Biology |
|
Research Statement: Evolution of gene regulatory networks; Long-range regulatory mechanisms; Mouse models for human disease Research Interests: Bioinformatics, Chromatin Structure, Development, Genomics, Molecular Evolution, Regulation of Gene Expression |
||
| [+][^] | Wilfred A van der Donk |
Affiliate, Department of Biochemistry |
|
Research Statement: The understanding of enzymatic transformations that are of pharmaceutical importance Research Interests: Drug Discovery, Enzymology, Molecular Evolution |
||
| [+][^] | Rachel J Whitaker |
Assistant Professor of Microbiology |
|
Research Statement: Microbial ecology and evolution Research Interests: Archaea, Bioinformatics, Genomics, Host-Pathogen Interactions, Microbial Ecology, Molecular Evolution |
||
| [+][^] | Carl R Woese |
Professor of Microbiology |
|
Research Statement: Molecular evolution of prokaryotes; structure-function of protein translation apparatus Research Interests: Archaea, Genomics, Molecular Evolution |
||
Molecular Immunology
| [+][^] | Steven R Blanke |
Professor of Microbiology |
|
Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | David M Kranz |
Professor of Biochemistry |
|
Research Statement: Structure, Function, and Engineering of T Cell Receptors; Molecular Basis of Immune Recognition by T Cells; Tumor Targeting with T Cells; Engineering Protein Therapeutics Research Interests: Molecular Immunology, Protein Dynamics, Protein Structure, Receptor Biochemistry |
||
| [+][^] | Ed Roy |
Affiliate, Department of Molecular and Integrative Physiology |
|
Research Statement: Immunotherapy Research Interests: Molecular Immunology |
||
| [+][^] | Joanna L. Shisler |
Associate Professor of Microbiology |
|
Research Statement: Immune evasion strategies of viruses; viral mechanisms to inhibit inflammation; host-pathogen interactions Research Interests: Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Virology Disease Research Topics: Infectious Diseases |
||
| [+][^] | Richard I Tapping |
Associate Professor of Microbiology |
|
Research Statement: The Role of Toll-like Receptors in Host Innate Immune Defense. The genetic basis of host resistance to Yersinia pestis infection. Research Interests: Genomics, Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry Disease Research Topics: Infectious Diseases |
||
| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
|
Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
||
Neurobiology
| [+][^] | Thomas J Anastasio |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Multilevel modeling of neurobiological systems in health and disease. Research Interests: Computational Biology, Neurobiology Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Stephanie Ceman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Molecular basis of disease, post-translational modifications, regulation of RNA expression, RNA-protein interactions Research Interests: Neurobiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Hee Jung Chung |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Activity-dependent regulation of ion channels in Synaptic and Intrinsic Plasticity Research Interests: Ion Channels, Learning and Memory, Neurobiology Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | David F Clayton |
Professor of Cell and Developmental Biology |
|
Research Statement: Neurogenomics; cellular mechanisms of neural plasticity; songbird model system Research Interests: Genomics, Learning and Memory, Neurobiology |
||
| [+][^] | Charles "Lee" Cox |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Functional organization and neuromodulation of thalamocortical circuits, Neuronal excitability, Synaptic Physiology and Plasticity. Fragile X Syndrome, Epilepsy, Alzheimer's Disease Research Interests: Imaging, Ion Channels, Learning and Memory, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Albert S Feng |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural basis of sound pattern recognition Research Interests: Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing |
||
| [+][^] | Julia M George |
Research Associate Professor of Cell and Developmental Biology |
|
Research Statement: Synuclein proteins and neurodegenerative disease Research Interests: Membrane Biology, Neurobiology, Protein Structure Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Martha U Gillette |
Alumni Professor of Cell and Developmental Biology |
|
Research Statement: The neurobiology of time; engineering neuronal development and repair Research Interests: Cytoskeleton, Development, Neurobiology, Proteomics, Signal Transduction Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Rhanor Gillette |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural Bases of Decision Research Interests: Computational Biology, Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | William Greenough |
Professor Emeritus of Molecular and Integrative Physiology |
|
Research Statement: Brain plasticity in learning and memory; cellular signalling in brain plasticity; mechanisms of brain development; role of experience in brain maturation Research Interests: Development, Learning and Memory, Neurobiology |
||
| [+][^] | Claudio Grosman |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Molecular Mechanisms of Neurotransmitter-gated Ion Channels Research Interests: Ion Channels, Membrane Biology, Neurobiology, Protein Dynamics Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Daniel Llano |
Assistant Professor in Molecular and Integrative Physiology and the College of Medicine |
|
Research Statement: The role of top-down projections in the processing of complex sounds Research Interests: Computational Biology, Imaging, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Esmail "Essie" Meisami |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Brain development; hormones & growth factors in recovery from early neural retardation; neurobiology of the olfactory system Research Interests: Development, Neurobiology, Sensory Processing |
||
| [+][^] | Mark E Nelson |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Computational Neuroscience; Neuroethology; Adaptive Behaviour Research Interests: Computational Biology, Learning and Memory, Neurobiology, Sensory Processing |
||
| [+][^] | Victor D Ramirez |
Professor Emeritus of Molecular and Integrative Physiology |
|
Research Statement: Molecular Neuroendocrinology Research Interests: Endocrinology, Neurobiology, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
|
Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Jonathan V Sweedler |
Affiliate, Department of Molecular and Integrative Physiology |
|
Research Statement: Novel neurochemistry and the function of cell-to-cell signaling molecules on neuronal network activity Research Interests: Neurobiology |
||
Pattern Formation
| [+][^] | Jo Ann Cameron |
Professor Emerita of Cell and Developmental Biology |
|
Research Statement: Cellular and molecular mechanisms that control amphibian limb regeneration Research Interests: Development, Pattern Formation |
||
| [+][^] | Albert S Feng |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural basis of sound pattern recognition Research Interests: Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing |
||
| [+][^] | Rhanor Gillette |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural Bases of Decision Research Interests: Computational Biology, Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Phillip A Newmark |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Planarian regeneration, germ cell development, schistosomes Research Interests: Development, Pattern Formation, Reproductive Biology Disease Research Topics: Infectious Diseases, Reproductive Diseases and Infertility |
||
| [+][^] | Rachel Smith-Bolton |
Assistant Professor of Cell and Developmental Biology |
|
Research Statement: Wound repair and tissue regeneration; Drosophila genetics; Development and patterning Research Interests: Development, Pattern Formation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Trauma, Bleeding & Tissue Regeneration |
||
Protein Dynamics
| [+][^] | Brian C Freeman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Hsp90 Chaperone System Chromatin Landmarks Gene Regulation Telomere Biology Research Interests: Genomics, Protein Dynamics, Protein-Nucleic Acid Interactions, Proteomics, Regulation of Gene Expression Disease Research Topics: Cancer |
||
| [+][^] | John A Gerlt |
Professor of Biochemistry |
|
Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
||
| [+][^] | Claudio Grosman |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Molecular Mechanisms of Neurotransmitter-gated Ion Channels Research Interests: Ion Channels, Membrane Biology, Neurobiology, Protein Dynamics Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | David M Kranz |
Professor of Biochemistry |
|
Research Statement: Structure, Function, and Engineering of T Cell Receptors; Molecular Basis of Immune Recognition by T Cells; Tumor Targeting with T Cells; Engineering Protein Therapeutics Research Interests: Molecular Immunology, Protein Dynamics, Protein Structure, Receptor Biochemistry |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | M Ashley Spies |
Research Assistant Professor of Biochemistry |
|
Research Statement: Computer-aided Drug Discovery (CADD); Computational Chemistry: QC/MM applied to Enzyme Catalysis; Virtual Screening; kinetic isotope effects; kinetics; origins of enzyme catalytic power; bioorganic chemistry; amino acid racemases and epimerases; pyridoxal-5'-phosphate (PLP) chemistry and enzymology Research Interests: Computational Biology, Drug Discovery, Enzymology, Protein Dynamics Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
||
| [+][^] | Emad Tajkhorshid |
Associate Professor of Biochemistry |
|
Research Statement: Computational Studies of Membranes and Membrane Associated Phenomena Research Interests: Computational Biology, Ion Channels, Membrane Biology, Protein Dynamics, Protein Structure |
||
| [+][^] | Colin A Wraight |
Professor of Biochemistry |
|
Research Statement: Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions Research Interests: Bioenergetics and Photosynthesis, Enzymology, Membrane Biology, Protein Dynamics, Protein Structure |
||
Protein Structure
| [+][^] | Antony R Crofts |
Professor Emeritus of Biochemistry |
|
Research Statement: Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere Research Interests: Bioenergetics and Photosynthesis, Computational Biology, Enzymology, Ion Channels, Membrane Biology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Metabolic Disorders/Diabetes |
||
| [+][^] | Robert "Bob" B Gennis |
Professor of Biochemistry |
|
Research Statement: Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Bioinformatics, Enzymology, Membrane Biology, Microbial Ecology, Microbial Physiology, Molecular Evolution, Protein Structure Disease Research Topics: Infectious Diseases |
||
| [+][^] | Julia M George |
Research Associate Professor of Cell and Developmental Biology |
|
Research Statement: Synuclein proteins and neurodegenerative disease Research Interests: Membrane Biology, Neurobiology, Protein Structure Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | John A Gerlt |
Professor of Biochemistry |
|
Research Statement: Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production Research Interests: Biofuels, Bioinformatics, Enzymology, Genomics, Microbial Physiology, Molecular Evolution, Protein Dynamics, Protein Structure |
||
| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
|
Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
||
| [+][^] | David M Kranz |
Professor of Biochemistry |
|
Research Statement: Structure, Function, and Engineering of T Cell Receptors; Molecular Basis of Immune Recognition by T Cells; Tumor Targeting with T Cells; Engineering Protein Therapeutics Research Interests: Molecular Immunology, Protein Dynamics, Protein Structure, Receptor Biochemistry |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | James H. Morrissey |
Professor of Biochemistry |
|
Research Statement: Protein-phospholipid interactions; regulation of protease cascades; blood clotting; polyphosphate Research Interests: Enzymology, Membrane Biology, Protein Structure Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Trauma, Bleeding & Tissue Regeneration |
||
| [+][^] | Satish K Nair |
Associate Professor of Biochemistry |
|
Research Statement: X-ray crystallography, gene regulation, DNA-protein interactions Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
||
| [+][^] | Mary A Schuler |
Professor of Cell and Developmental Biology |
|
Research Statement: Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases Research Interests: Drug Discovery, Enzymology, Genomics, Protein Structure, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
|
Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Emad Tajkhorshid |
Associate Professor of Biochemistry |
|
Research Statement: Computational Studies of Membranes and Membrane Associated Phenomena Research Interests: Computational Biology, Ion Channels, Membrane Biology, Protein Dynamics, Protein Structure |
||
| [+][^] | Colin A Wraight |
Professor of Biochemistry |
|
Research Statement: Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions Research Interests: Bioenergetics and Photosynthesis, Enzymology, Membrane Biology, Protein Dynamics, Protein Structure |
||
| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
|
Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
||
Protein-Nucleic Acid Interactions
| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Isaac K O Cann |
Professor of Microbiology and Animal Sciences |
|
Research Statement: Molecular biology and biochemistry of archaeal DNA replication; enzymes of plant cell wall hydrolysis Research Interests: Archaea, Biofuels, Genomics, Protein-Nucleic Acid Interactions |
||
| [+][^] | Stephanie Ceman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Molecular basis of disease, post-translational modifications, regulation of RNA expression, RNA-protein interactions Research Interests: Neurobiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Lin-Feng Chen |
Assistant Professor of Biochemistry |
|
Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Stephen K Farrand |
Professor of Microbiology |
|
Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
||
| [+][^] | Brian C Freeman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Hsp90 Chaperone System Chromatin Landmarks Gene Regulation Telomere Biology Research Interests: Genomics, Protein Dynamics, Protein-Nucleic Acid Interactions, Proteomics, Regulation of Gene Expression Disease Research Topics: Cancer |
||
| [+][^] | Jeffrey F Gardner |
Professor of Microbiology |
|
Research Statement: Mechanism of site-specific recombination by bacteriophages and conjugative transposons; mechanisms of protein recognition of DNA Research Interests: Bacterial Genetics, Protein-Nucleic Acid Interactions |
||
| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
|
Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
||
| [+][^] | Benita S Katzenellenbogen |
Swanlund Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors and their genome-wide activities Research Interests: Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Lyne Levesque |
Research Assistant Professor of Cell and Developmental Biology |
|
Research Statement: Ins and outs of nucleocytoplasmic transport Research Interests: Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Virology Disease Research Topics: Infectious Diseases |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | Susan A Martinis |
Professor and Head of Biochemistry |
|
Research Statement: RNA structure and function, RNA-protein interactions,| chemical mechanisms of biological reactions, protein synthesis, tRNA synthetases Research Interests: Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | Craig Mizzen |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Chromatin structure, function and metabolism. Roles of histone modifications and other epigenetic factors in normal development and disease. Research Interests: Chromatin Structure, Protein-Nucleic Acid Interactions, Regulation of Gene Expression Disease Research Topics: Cancer |
||
| [+][^] | Satish K Nair |
Associate Professor of Biochemistry |
|
Research Statement: X-ray crystallography, gene regulation, DNA-protein interactions Research Interests: Archaea, Biofuels, Drug Discovery, Enzymology, Membrane Biology, Protein Structure, Protein-Nucleic Acid Interactions Disease Research Topics: Infectious Diseases, Metabolic Disorders/Diabetes |
||
| [+][^] | Ann M Nardulli |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection Research Interests: Chromatin Structure, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | K V Prasanth |
Assistant Professor of Cell and Developmental Biology |
|
Research Statement: long noncoding RNA; Gene regulation; Nuclear domain & structure Research Interests: Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology Disease Research Topics: Cancer |
||
| [+][^] | Supriya Prasanth |
Assistant Professor of Cell and Developmental Biology |
|
Research Statement: Eukaryotic DNA replication; Chromosome structure & maintenance; Heterochromatin organization; Cell cycle control Research Interests: Chromatin Structure, Protein-Nucleic Acid Interactions |
||
| [+][^] | David H Rivier |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Regulation of chromosomal DNA replication; structure of chromosomal origins; relationship between DNA replication and stable, heritable transcription states (position effects); yeast molecular genetics Research Interests: Protein-Nucleic Acid Interactions |
||
| [+][^] | Scott K Silverman |
Professor of Chemistry |
|
Research Statement: DNA as an enzyme Research Interests: DNA Biology, Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | Maria Spies |
Assistant Professor of Biochemistry |
|
Research Statement: Molecular mechanisms of DNA helicases and DNA motor proteins; mechanistic aspects of protein-nucleic acids and protein-protein interactions; homologous genetic recombination; DNA repair; molecular motors Research Interests: DNA Biology, Protein-Nucleic Acid Interactions Disease Research Topics: Cancer |
||
| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
|
Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
||
Proteomics
| [+][^] | Brian C Freeman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Hsp90 Chaperone System Chromatin Landmarks Gene Regulation Telomere Biology Research Interests: Genomics, Protein Dynamics, Protein-Nucleic Acid Interactions, Proteomics, Regulation of Gene Expression Disease Research Topics: Cancer |
||
| [+][^] | Martha U Gillette |
Alumni Professor of Cell and Developmental Biology |
|
Research Statement: The neurobiology of time; engineering neuronal development and repair Research Interests: Cytoskeleton, Development, Neurobiology, Proteomics, Signal Transduction Disease Research Topics: Neurological and Behavioral Disorders |
||
Receptor Biochemistry
| [+][^] | Steven R Blanke |
Professor of Microbiology |
|
Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Lin-Feng Chen |
Assistant Professor of Biochemistry |
|
Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Benita S Katzenellenbogen |
Swanlund Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors and their genome-wide activities Research Interests: Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Stephen J Kaufman |
Professor of Cell and Developmental Biology, Emeritus |
|
Research Statement: Role of integrins and extracellular matrix proteins in skeletal muscle development, formation of the neuromuscular junction, and muscular dystrophy Research Interests: Cell-Matrix Interactions, Membrane Biology, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | David M Kranz |
Professor of Biochemistry |
|
Research Statement: Structure, Function, and Engineering of T Cell Receptors; Molecular Basis of Immune Recognition by T Cells; Tumor Targeting with T Cells; Engineering Protein Therapeutics Research Interests: Molecular Immunology, Protein Dynamics, Protein Structure, Receptor Biochemistry |
||
| [+][^] | Ann M Nardulli |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection Research Interests: Chromatin Structure, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Joanna L. Shisler |
Associate Professor of Microbiology |
|
Research Statement: Immune evasion strategies of viruses; viral mechanisms to inhibit inflammation; host-pathogen interactions Research Interests: Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Virology Disease Research Topics: Infectious Diseases |
||
| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
|
Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Richard I Tapping |
Associate Professor of Microbiology |
|
Research Statement: The Role of Toll-like Receptors in Host Innate Immune Defense. The genetic basis of host resistance to Yersinia pestis infection. Research Interests: Genomics, Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry Disease Research Topics: Infectious Diseases |
||
| [+][^] | Yang "Kevin" Xiang |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: GPCR signaling in Alzheimer's diseases and heart failure Research Interests: Learning and Memory, Membrane Biology, Receptor Biochemistry, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes, Neurological and Behavioral Disorders |
||
Regulation of Gene Expression
| [+][^] | Andrew S Belmont |
Professor of Cell and Developmental Biology |
|
Research Statement: Chromatin Structure, Gene expression, Nuclear Architecture Research Interests: Chromatin Structure, Imaging, Regulation of Gene Expression |
||
| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Stephanie Ceman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Molecular basis of disease, post-translational modifications, regulation of RNA expression, RNA-protein interactions Research Interests: Neurobiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Lin-Feng Chen |
Assistant Professor of Biochemistry |
|
Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | John E Cronan |
Professor and Head of Microbiology |
|
Research Statement: Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid Research Interests: Bacterial Genetics, Biofuels, Enzymology, Membrane Biology, Microbial Physiology, Regulation of Gene Expression |
||
| [+][^] | Stephen K Farrand |
Professor of Microbiology |
|
Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
||
| [+][^] | Brian C Freeman |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Hsp90 Chaperone System Chromatin Landmarks Gene Regulation Telomere Biology Research Interests: Genomics, Protein Dynamics, Protein-Nucleic Acid Interactions, Proteomics, Regulation of Gene Expression Disease Research Topics: Cancer |
||
| [+][^] | Benita S Katzenellenbogen |
Swanlund Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors and their genome-wide activities Research Interests: Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Stephen J Kaufman |
Professor of Cell and Developmental Biology, Emeritus |
|
Research Statement: Role of integrins and extracellular matrix proteins in skeletal muscle development, formation of the neuromuscular junction, and muscular dystrophy Research Interests: Cell-Matrix Interactions, Membrane Biology, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Jongsook Kim Kemper |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Nuclear Receptor Action in Metabolic Regulation: Applications to Metabolic Disorders including Fatty liver, Obesity, and Diabetes Research Interests: Chromatin Structure, Endocrinology, Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes |
||
| [+][^] | Kurt E Kwast |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Oxygen sensing, transcriptional regulation of oxygen-responsive genes, physiological genomics of oxygen regulation. Research Interests: Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Lyne Levesque |
Research Assistant Professor of Cell and Developmental Biology |
|
Research Statement: Ins and outs of nucleocytoplasmic transport Research Interests: Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Virology Disease Research Topics: Infectious Diseases |
||
| [+][^] | William W Metcalf |
Professor of Microbiology |
|
Research Statement: Molecular genetics and biochemistry of methanogenic Archaea; biosynthesis of phosphonate antibiotics; redox cycling of phosphorus by microorganisms Research Interests: Archaea, Bacterial Genetics, Bioenergetics and Photosynthesis, Drug Discovery, Genomics, Regulation of Gene Expression |
||
| [+][^] | Charles G Miller |
Professor of Microbiology |
|
Research Statement: Mechanisms of intracellular protein breakdown and proteolytic modification; structure/function relationships in peptide hydrolyzing enzymes Research Interests: Archaea, Bacterial Genetics, Microbial Physiology, Regulation of Gene Expression Disease Research Topics: Heart Disease, Stroke, and Thrombosis |
||
| [+][^] | Craig Mizzen |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Chromatin structure, function and metabolism. Roles of histone modifications and other epigenetic factors in normal development and disease. Research Interests: Chromatin Structure, Protein-Nucleic Acid Interactions, Regulation of Gene Expression Disease Research Topics: Cancer |
||
| [+][^] | Ann M Nardulli |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection Research Interests: Chromatin Structure, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | K V Prasanth |
Assistant Professor of Cell and Developmental Biology |
|
Research Statement: long noncoding RNA; Gene regulation; Nuclear domain & structure Research Interests: Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology Disease Research Topics: Cancer |
||
| [+][^] | Victor D Ramirez |
Professor Emeritus of Molecular and Integrative Physiology |
|
Research Statement: Molecular Neuroendocrinology Research Interests: Endocrinology, Neurobiology, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Abigail A Salyers |
Professor of Microbiology |
|
Research Statement: Antibiotic-resistance gene transfer; interaction of colonic bacteria with host; genetics of obligate anaerobes; conjugative transposons of Bacteroides Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Ecology, Microbial Physiology, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Mary A Schuler |
Professor of Cell and Developmental Biology |
|
Research Statement: Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases Research Interests: Drug Discovery, Enzymology, Genomics, Protein Structure, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | James M Slauch |
Professor of Microbiology |
|
Research Statement: Molecular mechanisms of Salmonella pathogenesis Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
||
| [+][^] | Rachel Smith-Bolton |
Assistant Professor of Cell and Developmental Biology |
|
Research Statement: Wound repair and tissue regeneration; Drosophila genetics; Development and patterning Research Interests: Development, Pattern Formation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Trauma, Bleeding & Tissue Regeneration |
||
| [+][^] | Lisa J Stubbs |
Professor of Cell and Developmental Biology |
|
Research Statement: Evolution of gene regulatory networks; Long-range regulatory mechanisms; Mouse models for human disease Research Interests: Bioinformatics, Chromatin Structure, Development, Genomics, Molecular Evolution, Regulation of Gene Expression |
||
| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
|
Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
||
| [+][^] | Benjamin D Williams |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Software for Medical Education Research Interests: Cell-Matrix Interactions, Regulation of Gene Expression |
||
| [+][^] | Huimin Zhao |
Centennial Endowed Chair Professor of Chemical and Biomolecular Engineering and Bioengineering |
|
Research Statement: Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis Research Interests: Biofuels, Bioinformatics, Drug Discovery, Enzymology, Molecular Immunology, Protein Structure, Regulation of Gene Expression Disease Research Topics: Infectious Diseases |
||
Reproductive Biology
| [+][^] | Milan K Bagchi |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Mechanisms of Steroid Hormone Signaling in Reproduction and Development Breast Cancer Research Interests: Endocrinology, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Benita S Katzenellenbogen |
Swanlund Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors and their genome-wide activities Research Interests: Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Ann M Nardulli |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection Research Interests: Chromatin Structure, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Phillip A Newmark |
Associate Professor of Cell and Developmental Biology |
|
Research Statement: Planarian regeneration, germ cell development, schistosomes Research Interests: Development, Pattern Formation, Reproductive Biology Disease Research Topics: Infectious Diseases, Reproductive Diseases and Infertility |
||
RNA Biology
| [+][^] | Paul J Hergenrother |
Professor of Chemistry |
|
Research Statement: Using small molecules to identify novel targets for the treatment of cancer, drug-resistant bacteria, and neurodegeneration Research Interests: Drug Discovery, RNA Biology Disease Research Topics: Cancer, Drug Discovery, Infectious Diseases |
||
| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
|
Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
||
| [+][^] | Lyne Levesque |
Research Assistant Professor of Cell and Developmental Biology |
|
Research Statement: Ins and outs of nucleocytoplasmic transport Research Interests: Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Virology Disease Research Topics: Infectious Diseases |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | Susan A Martinis |
Professor and Head of Biochemistry |
|
Research Statement: RNA structure and function, RNA-protein interactions,| chemical mechanisms of biological reactions, protein synthesis, tRNA synthetases Research Interests: Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | K V Prasanth |
Assistant Professor of Cell and Developmental Biology |
|
Research Statement: long noncoding RNA; Gene regulation; Nuclear domain & structure Research Interests: Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology Disease Research Topics: Cancer |
||
| [+][^] | Abigail A Salyers |
Professor of Microbiology |
|
Research Statement: Antibiotic-resistance gene transfer; interaction of colonic bacteria with host; genetics of obligate anaerobes; conjugative transposons of Bacteroides Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Ecology, Microbial Physiology, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Mary A Schuler |
Professor of Cell and Developmental Biology |
|
Research Statement: Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases Research Interests: Drug Discovery, Enzymology, Genomics, Protein Structure, Regulation of Gene Expression, RNA Biology |
||
| [+][^] | Scott K Silverman |
Professor of Chemistry |
|
Research Statement: DNA as an enzyme Research Interests: DNA Biology, Enzymology, Molecular Evolution, Protein-Nucleic Acid Interactions, RNA Biology |
||
| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
|
Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
||
Sensory Processing
| [+][^] | Charles "Lee" Cox |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Functional organization and neuromodulation of thalamocortical circuits, Neuronal excitability, Synaptic Physiology and Plasticity. Fragile X Syndrome, Epilepsy, Alzheimer's Disease Research Interests: Imaging, Ion Channels, Learning and Memory, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Stephen K Farrand |
Professor of Microbiology |
|
Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
||
| [+][^] | Albert S Feng |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural basis of sound pattern recognition Research Interests: Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing |
||
| [+][^] | Rhanor Gillette |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Neural Bases of Decision Research Interests: Computational Biology, Ion Channels, Learning and Memory, Neurobiology, Pattern Formation, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Daniel Llano |
Assistant Professor in Molecular and Integrative Physiology and the College of Medicine |
|
Research Statement: The role of top-down projections in the processing of complex sounds Research Interests: Computational Biology, Imaging, Neurobiology, Sensory Processing Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | Esmail "Essie" Meisami |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Brain development; hormones & growth factors in recovery from early neural retardation; neurobiology of the olfactory system Research Interests: Development, Neurobiology, Sensory Processing |
||
| [+][^] | Mark E Nelson |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Computational Neuroscience; Neuroethology; Adaptive Behaviour Research Interests: Computational Biology, Learning and Memory, Neurobiology, Sensory Processing |
||
Signal Transduction
| [+][^] | Milan K Bagchi |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Mechanisms of Steroid Hormone Signaling in Reproduction and Development Breast Cancer Research Interests: Endocrinology, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Philip M Best |
Associate Dean, College of LAS |
|
Research Statement: Calcium channels in the heart: structure, function and regulation Research Interests: Ion Channels, Signal Transduction |
||
| [+][^] | Steven R Blanke |
Professor of Microbiology |
|
Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Eric C. Bolton |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of development and homeostasis by hormonal signals Research Interests: Development, Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Jie Chen |
Professor of Cell and Developmental Biology |
|
Research Statement: Nutrient-sensing signal transduction in mammalian cell growth, differentiation, and metabolism Research Interests: Development, Endocrinology, Signal Transduction Disease Research Topics: Cancer, Metabolic Disorders/Diabetes, Trauma, Bleeding & Tissue Regeneration |
||
| [+][^] | Lin-Feng Chen |
Assistant Professor of Biochemistry |
|
Research Statement: Epigenetic regulation of NF-κB; the role of NF-κB in apoptosis and cancer; cross-talk between NF-κB and other signaling pathways. Research Interests: Chromatin Structure, Endocrinology, Host-Pathogen Interactions, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Cancer, Infectious Diseases |
||
| [+][^] | Stephen K Farrand |
Professor of Microbiology |
|
Research Statement: Molecular biology of the Agrobacterium-plant interaction Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Microbial Physiology, Molecular Evolution, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, Sensory Processing, Signal Transduction |
||
| [+][^] | Martha U Gillette |
Alumni Professor of Cell and Developmental Biology |
|
Research Statement: The neurobiology of time; engineering neuronal development and repair Research Interests: Cytoskeleton, Development, Neurobiology, Proteomics, Signal Transduction Disease Research Topics: Neurological and Behavioral Disorders |
||
| [+][^] | Benita S Katzenellenbogen |
Swanlund Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors and their genome-wide activities Research Interests: Endocrinology, Genomics, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer, Reproductive Diseases and Infertility |
||
| [+][^] | Stephen J Kaufman |
Professor of Cell and Developmental Biology, Emeritus |
|
Research Statement: Role of integrins and extracellular matrix proteins in skeletal muscle development, formation of the neuromuscular junction, and muscular dystrophy Research Interests: Cell-Matrix Interactions, Membrane Biology, Receptor Biochemistry, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Jongsook Kim Kemper |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Nuclear Receptor Action in Metabolic Regulation: Applications to Metabolic Disorders including Fatty liver, Obesity, and Diabetes Research Interests: Chromatin Structure, Endocrinology, Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes |
||
| [+][^] | Kurt E Kwast |
Associate Professor of Molecular and Integrative Physiology |
|
Research Statement: Oxygen sensing, transcriptional regulation of oxygen-responsive genes, physiological genomics of oxygen regulation. Research Interests: Genomics, Metabolic Regulation, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Yi Lu |
Professor of Chemistry |
|
Research Statement: Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors Research Interests: Bioenergetics and Photosynthesis, Biofuels, Bioinformatics, DNA Biology, Enzymology, Genomics, Imaging, Molecular Evolution, Protein Dynamics, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Sensory Processing, Signal Transduction |
||
| [+][^] | Ann M Nardulli |
Professor of Molecular and Integrative Physiology |
|
Research Statement: Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection Research Interests: Chromatin Structure, Endocrinology, Protein-Nucleic Acid Interactions, Receptor Biochemistry, Regulation of Gene Expression, Reproductive Biology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Lori T Raetzman |
Assistant Professor of Molecular and Integrative Physiology |
|
Research Statement: Notch signaling pathway in pituitary gland development and disease Research Interests: Development, Endocrinology, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Victor D Ramirez |
Professor Emeritus of Molecular and Integrative Physiology |
|
Research Statement: Molecular Neuroendocrinology Research Interests: Endocrinology, Neurobiology, Regulation of Gene Expression, Signal Transduction |
||
| [+][^] | Joanna L. Shisler |
Associate Professor of Microbiology |
|
Research Statement: Immune evasion strategies of viruses; viral mechanisms to inhibit inflammation; host-pathogen interactions Research Interests: Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Virology Disease Research Topics: Infectious Diseases |
||
| [+][^] | Stephen G Sligar |
Director of the School of Molecular and Cellular Biology |
|
Research Statement: Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration. Research Interests: Drug Discovery, Endocrinology, Enzymology, Membrane Biology, Neurobiology, Protein Structure, Receptor Biochemistry, Signal Transduction Disease Research Topics: Cancer |
||
| [+][^] | Rachel Smith-Bolton |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Wound repair and tissue regeneration; Drosophila genetics; Development and patterning Research Interests: Development, Pattern Formation, Regulation of Gene Expression, Signal Transduction Disease Research Topics: Trauma, Bleeding & Tissue Regeneration |
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| [+][^] | Cari Vanderpool |
Assistant Professor of Microbiology |
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Research Statement: Regulation of Bacterial Stress Responses Research Interests: Bacterial Genetics, Genomics, Host-Pathogen Interactions, Microbial Physiology, Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Signal Transduction |
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| [+][^] | Fei Wang |
Assistant Professor of Cell and Developmental Biology |
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Research Statement: Human pluripotent stem cells; neutrophil polarity and chemotaxis Research Interests: Cell-Matrix Interactions, Cytoskeleton, Development, Imaging, Signal Transduction Disease Research Topics: Drug Discovery |
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| [+][^] | Brenda Anne Wilson |
Associate Professor of Microbiology |
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Research Statement: Bacterial protein toxins, their interaction with host cells, their effects on intracellular signal transduction, and development of novel alternative anti-toxin therapeutics; human and nonhuman primate vaginal microbial ecosystems and their role in health and disease Research Interests: Host-Pathogen Interactions, Microbial Ecology, Signal Transduction, Toxins Disease Research Topics: Drug Discovery, Infectious Diseases, Neurological and Behavioral Disorders, Reproductive Diseases and Infertility |
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| [+][^] | Yang "Kevin" Xiang |
Assistant Professor of Molecular and Integrative Physiology |
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Research Statement: GPCR signaling in Alzheimer's diseases and heart failure Research Interests: Learning and Memory, Membrane Biology, Receptor Biochemistry, Signal Transduction Disease Research Topics: Heart Disease, Stroke, and Thrombosis, Metabolic Disorders/Diabetes, Neurological and Behavioral Disorders |
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Toxins
| [+][^] | Steven R Blanke |
Professor of Microbiology |
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Research Statement: Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins Research Interests: Bacterial Genetics, Host-Pathogen Interactions, Membrane Biology, Microbial Physiology, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Toxins Disease Research Topics: Cancer, Infectious Diseases |
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| [+][^] | Raven H Huang |
Associate Professor of Biochemistry |
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Research Statement: Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair. Research Interests: Enzymology, Host-Pathogen Interactions, Molecular Evolution, Protein Structure, Protein-Nucleic Acid Interactions, RNA Biology, Toxins |
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| [+][^] | Douglas A. Mitchell |
Assistant Professor of Chemistry |
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Research Statement: Molecular underpinnings of bacterial virulence Research Interests: Bioinformatics, Drug Discovery, Enzymology, Host-Pathogen Interactions, Toxins |
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| [+][^] | Brenda Anne Wilson |
Associate Professor of Microbiology |
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Research Statement: Bacterial protein toxins, their interaction with host cells, their effects on intracellular signal transduction, and development of novel alternative anti-toxin therapeutics; human and nonhuman primate vaginal microbial ecosystems and their role in health and disease Research Interests: Host-Pathogen Interactions, Microbial Ecology, Signal Transduction, Toxins Disease Research Topics: Drug Discovery, Infectious Diseases, Neurological and Behavioral Disorders, Reproductive Diseases and Infertility |
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Virology
| [+][^] | Lyne Levesque |
Research Assistant Professor of Cell and Developmental Biology |
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Research Statement: Ins and outs of nucleocytoplasmic transport Research Interests: Protein-Nucleic Acid Interactions, Regulation of Gene Expression, RNA Biology, Virology Disease Research Topics: Infectious Diseases |
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| [+][^] | Joanna L. Shisler |
Associate Professor of Microbiology |
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Research Statement: Immune evasion strategies of viruses; viral mechanisms to inhibit inflammation; host-pathogen interactions Research Interests: Host-Pathogen Interactions, Molecular Immunology, Receptor Biochemistry, Signal Transduction, Virology Disease Research Topics: Infectious Diseases |
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