Faculty Research Interests

Archaea . Bioenergetics and Photosynthesis . Biofuels . Bioinformatics
Cell-Cell Interactions . Cell-Matrix Interactions . Chromatin Structure
Computational Biology . Cytoskeleton . Development . DNA Biology
Drug Discovery . Endocrinology . Enzymology . Genetics . Genomics . Glycobiology
Host-Pathogen Interactions . Imaging . Ion Channels . Learning and Memory
Membrane Biology . Metabolic Regulation . Microbial Ecology
Microbial Physiology . Molecular Evolution . Molecular Immunology
Neurobiology . Pattern Formation . Protein Dynamics . Protein Structure
Protein Synthesis . Protein-Nucleic Acid Interactions . Proteomics
Receptor Biochemistry . Regulation of Gene Expression
Reproductive Biology . RNA Biology . Sensory Processing
Signal Transduction . Toxins . Virology

Isaac K O Cann

Isaac K O Cann

Microbology

Molecular biology and biochemistry of archaeal DNA replication; enzymes of plant cell wall hydrolysis

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1105 Institute for Genomic Biology, 1206 West Gregory Drive | MC-195
Urbana, IL 61801
Office: (217) 333-2090

Robert "Bob" B Gennis

Robert "Bob" B Gennis

Biochemistry

Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential

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A320 CLSL
Office: (217) 333-9075
Lab: (217) 333-4939
Fax: (217) 244-3186

William W Metcalf

William W Metcalf

Microbology

Molecular genetics and biochemistry of methanogenic Archaea; biosynthesis of phosphonate antibiotics; redox cycling of phosphorus by microorganisms

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Office: (217) 244-1943
Lab: (217) 265-0771

Satish K Nair

Satish K Nair

Biochemistry

Natural products biosynthesis, bacterial signalling, X-ray crystallography

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430 Roger Adams Lab
Office: (217) 333-0641
Lab: (217) 333-2688
Fax: (217) 244-5858

Gary J Olsen

Gary J Olsen

Microbology

The functions, evolutionary histories and structures of genes and proteins

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383 Morrill Hall
Office: (217) 244-0616
Lab: (217) 244-0617
Fax: (217) 244-6697

Rachel J Whitaker

Rachel J Whitaker

Microbology

For most current information and news please visit our lab website at www.life.illinois.edu/whitaker/

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C222 CLSL
Office: (217) 244-8420

Ralph S Wolfe

Ralph S Wolfe

Microbology

Biochemistry of methanogens

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Office: (217) 333-0065

Antony R Crofts

Antony R Crofts

Biochemistry

Structure/function relationships in photosynthetic energy conversion; structure of membrane proteins; mechanism of energy conservation; photosynthesis in intact plants; energetics of the biosphere

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153 Davenport Hall
Office: (217) 333-2043
Lab: (217) 333-7407
Fax: (217) 244-6615

Yi Lu

Yi Lu

Biochemistry

Protein design and engineering; in vitro selection and characterization of new catalytic DNA and RNA molecules as anti-viral pharmaceutical agents or as metal ion biosensors

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A324 CLSL
Office: (217) 333-2619
Fax: (217) 333-2685

Colin A Wraight

Colin A Wraight

Biochemistry

Electron and proton transfer in proteins and across membranes; biological energy conversion; control of redox cofactor function; molecular engineering of ligand-protein interactions

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160 Davenport Hall
Office: (217) 333-3245
Lab: (217) 333-8725
Fax: (217) 244-6615

John E Cronan

John E Cronan

Microbology

Genetic approaches to regulation of lipid metabolism; synthesis and attachment of biotin and lipoic acid

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B103 CLSL
Office: (217) 333-7919
Lab: (217) 244-3466
Fax: (217) 244-6697

John A Gerlt

John A Gerlt

Biochemistry

Mechanisms of enzyme-catalyzed reactions, functional genomics, lignin deconstruction for biofuel production

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Curriculum Vita

3107 IGB
Office: (217) 244-7414
Lab: (217) 333-2699
Fax: (217) 244-6538

Huimin Zhao

Huimin Zhao

Biochemistry

Synthetic biology; protein engineering; metabolic engineering; biocatalysis; biosynthesis

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215 Rogers Adams Lab
Office: (217) 333-2631
Fax: (217) 333-5052

Patrick Degnan

Patrick Degnan

Microbology

Genome-enabled examination of diversity, genome evolution and processes in complex microbial communities

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Morrill Hall 371
Office: (217) 244-5504
Fax: (217) 244-6697

Jeffrey Haas

Jeffrey Haas

Molecular & Cellular Biology

Office: (217) 333-7525
Lab: (217) 265-0178

Auinash Kalsotra

Auinash Kalsotra

Biochemistry

Tissue development, regeneration and disease, MicroRNAs, Myotonic dystrophy, RNA therapeutics

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Office: 461 Medical Science Building,
506 South Mathews Ave.,
Urbana, IL 61801
Office: (217) 300-7654
Lab: (217) 300-5531
Fax: (217) 244-5858

Douglas A. Mitchell

Douglas A. Mitchell

Microbology

Molecular underpinnings of bacterial virulence

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room 3105 IGB (main office) and room 345 RAL
Office: (217) 333-1345

Hugh M Robertson

Hugh M Robertson

Cell & Developmental Biology

Molecular basis of insect olfaction; molecular evolution of DNA transposons; comparative insect genomics; molecular evolution of nematode chemoreceptors

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417 Morrill Hall
Office: (217) 333-0489
Lab: (217) 333-0489
Fax: (217) 244-3499

Lisa J Stubbs

Lisa J Stubbs

Cell & Developmental Biology

Evolution of gene regulatory networks; Long-range regulatory mechanisms; Mouse models of human disease

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R2402 Institute for Genomic Biology
Office: (217) 244-4000
Fax: (217) 244-1781

Eric C. Bolton

Eric C. Bolton

Molecular & Integrative Physiology

Regulation of prostate development and growth by hormonal signals

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446A Burrill Hall
Office: (217) 244-0535
Lab: (217) 244-0445
Fax: (217) 333-1133

William M Brieher

William M Brieher

Cell & Developmental Biology

Cytoskeleton and Cell Adhesion

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B615, CLSL
Office: (217) 333-3272
Lab: (217) 333-9166

Deborah E Leckband

Deborah E Leckband

Biochemistry

Molecular Mechanisms of Cell Adhesion; Cell Engineering

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127 Roger Adams Lab
Office: (217) 244-0793
Lab: (217) 244-2007
Fax: (217) 333-5052

Vivian W Tang

Vivian W Tang

Cell & Developmental Biology

Cell Junctions in Health and Disease

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Office: 539B Morrill Hall

Stephen J Kaufman

Stephen J Kaufman

Cell & Developmental Biology

Role of integrins and extracellular matrix proteins in skeletal muscle development, formation of the neuromuscular junction, and muscular dystrophy

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287 Burrill Hall
Fax: (217) 244-1648

Benjamin  D Williams

Benjamin D Williams

Software for Medical Education

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B615 CLSL
Office: (217) 244-9650
Lab: (217) 333-9166
Fax: (217) 244-1648

Andrew S Belmont

Andrew S Belmont

Cell & Developmental Biology

Chromatin Structure, Gene expression, Nuclear Architecture

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B509 CLSL
Office: (217) 244-2311
Lab: (217) 333-8372
Fax: (217) 244-1648

Jongsook Kim Kemper

Jongsook Kim Kemper

Molecular & Integrative Physiology

Nuclear Receptor Action in Metabolic Regulation: Applications to Metabolic Disorders including Fatty liver, Obesity, and Diabetes

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394 Burrill Hall
Office: (217) 333-6317
Lab: (217) 244-2236
Fax: (217) 333-1133

Craig Mizzen

Craig Mizzen

Cell & Developmental Biology

Chromatin structure, function and metabolism. Roles of histone modifications and other epigenetic factors in normal development and disease.

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565B Morrill Hall
Office: (217) 244-4896
Lab: (217) 265-6439
Fax: (217) 244-1648

Ann M Nardulli

Ann M Nardulli

Molecular & Integrative Physiology

Regulation of estrogen-responsive genes; role of estrogen-induced oxidative stress and DNA repair proteins in mammary carcinogenesis and breast cancer progression; mechanisms by which estrogen promotes neuroprotection

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513 Burrill Hall
Office: (217) 244-5679
Lab: (217) 244-6143
Fax: (217) 333-1133

Supriya Prasanth

Supriya Prasanth

Cell & Developmental Biology

Eukaryotic DNA replication; Chromosome structure & maintenance; Heterochromatin organization; Cell cycle control

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C422 CLSL
Office: (217) 244-8076
Lab: (217) 244-8084
Fax: (217) 244-1648

David J Shapiro

David J Shapiro

Biochemistry

Identification and use of novel small molecule biomodulators to identify and analyze pathways important in cancer and development of these small molecules as potential anticancer drugs.

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314d Roger Adams Lab
Office: (217) 333-1788
Lab: (217) 244-0207
Fax: (217) 244-5858

Thomas J Anastasio

Thomas J Anastasio

Molecular & Integrative Physiology

Multilevel modeling of neurobiological systems in health and disease.

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4165 Beckman Institute
Office: (217) 244-2895
Lab: (217) 244-5913
Fax: (217) 244-5180

Rhanor Gillette

Rhanor Gillette

Molecular & Integrative Physiology

Neural Bases of Decision

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414 Burrill Hall
Office: (217) 333-0328
Lab: (217) 244-5741
Fax: (217) 333-1133

Daniel Llano

Daniel Llano

Molecular & Integrative Physiology

The role of top-down projections in the processing of complex sounds

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2355 Beckman Institute
405 North Mathews Avenue
Urbana, IL 61801
Office: (217) 244-0740
Lab: (217) 244-0755

Jay E Mittenthal

Jay E Mittenthal

Cell & Developmental Biology

Computational biology: Design and evolution of molecular networks

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516 Morrill Hall
Office: (217) 333-4846
Fax: (217) 244-1648

Mark E Nelson

Mark E Nelson

Molecular & Integrative Physiology

Computational Neuroscience; Neuroethology; Adaptive Behaviour

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5251 Beckman Institute
MC-251
Office: (217) 244-1371

Emad Tajkhorshid

Emad Tajkhorshid

Biochemistry

Computational Studies of Membrane Proteins and Membrane Associated Phenomena

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3009 Beckman Institute
Office: (217) 244-6914

Martha U Gillette

Martha U Gillette

Cell & Developmental Biology

The neurobiology of time; engineering neuronal development and repair

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618 Morrill Hall
Office: (217) 244-1355
Lab: (217) 244-1842
Fax: (217) 244-1648

Jo Ann  Cameron

Jo Ann Cameron

Cell & Developmental Biology

Cellular and molecular mechanisms that control amphibian limb regeneration

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2103 IGB
Office: (217) 333-1254
Lab: (217) 333-1254
Fax: (217) 244-1648

Jie Chen

Jie Chen

Cell & Developmental Biology

Nutrient-sensing signal transduction in mammalian cell growth, differentiation, and metabolism

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C526 CLSL
Office: (217) 265-0674
Lab: (217) 265-0672
Fax: (217) 265-0674

William Greenough

William Greenough

Neuroscience

Brain plasticity in learning and memory; cellular signalling in brain plasticity; mechanisms of brain development; role of experience in brain maturation

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2325 Beckman Institute
Office: (217) 333-4472
Lab: (217) 333-1838
Fax: (217) 244-5180

Phillip A Newmark

Phillip A Newmark

Cell & Developmental Biology

Planarian regeneration, germ cell development, schistosomes

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C622 CLSL
Office: (217) 244-5353
Lab: (217) 244-4504
Fax: (217) 244-1648

Lori  T Raetzman

Lori T Raetzman

Molecular & Integrative Physiology

Notch signaling pathway in pituitary gland development and disease

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535 Burrill Hall
Office: (217) 244-6233
Lab: (217) 333-7913
Fax: (217) 333-1133

Gene E Robinson

Gene E Robinson

Cell & Developmental Biology

From society to genes

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449 Morrill Hall
Office: (217) 265-0309
Lab: (217) 333-6843
Fax: (217) 244-3499

Rachel Smith-Bolton

Rachel Smith-Bolton

Cell & Developmental Biology

Wound repair and tissue regeneration; Drosophila genetics; Development and patterning

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CLSL C626
Office: (217) 244-4183
Lab: (217) 244-4512

Fei Wang

Fei Wang

Cell & Developmental Biology

Human pluripotent stem cells; early embryonic development; neutrophil polarity and chemotaxis

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B521 CLSL
Office: (217) 333-5972
Lab: (217) 333-6007

Andrei Kuzminov

Andrei Kuzminov

Microbology

Mechanisms of DNA replication stress and genome instability

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C326 CLSL
Office: (217) 265-0329
Lab: (217) 265-0852

Scott K Silverman

Scott K Silverman

Biochemistry

DNA as an enzyme

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140 Roger Adams Lab
Office: (217) 244-4489
Fax: (217) 244-8024

Paul J Hergenrother

Paul J Hergenrother

Biochemistry

Using small molecules to identify novel targets for the treatment of cancer, drug-resistant bacteria, and neurodegeneration

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261 Roger Adams Lab
Office: (217) 333-0363
Lab: (217) 333-3694
Fax: (217) 244-8024

Hong Jin

Hong Jin

Biochemistry

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493 Roger Adams Laboratory
Office: (217) 244-9493
Lab: (217) 333-3944
Fax: (217) 244-5858

Mary A Schuler

Mary A Schuler

Cell & Developmental Biology

Molecular biology, biochemistry and genomics: pre-mRNA processing and P450 monooxygenases

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161 Edward R. Madigan Laboratory (ERML)
Office: (217) 333-8784
Lab: (217) 333-8785
Fax: (217) 244-1336

Stephen G Sligar

Stephen G Sligar

Biochemistry

Structural and functional characterization of macromolecular assemblies and the enzymes of biological oxidations, nanoscale systems for human therapeutics, genome/proteome analysis, macromolecular signaling and the biological details of cell migration.

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116 Morrill Hall
Office: (217) 244-7395
Lab: (217) 244-5329
Fax: (217) 265-4073

Wilfred A van der Donk

Wilfred A van der Donk

Biochemistry

The understanding of enzymatic transformations that are of pharmaceutical importance

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161 Roger Adams Lab
Office: (217) 244-5360
Lab: (217) 333-3896
Fax: (217) 244-8024

Sayeepriyadarshini "Sayee" Anakk

Sayeepriyadarshini "Sayee" Anakk

Molecular & Integrative Physiology

Liver metabolism in normal and diseased state

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453 Medical School Building
Office: (217) 300-7905
Fax: (217) 244-5858

Milan K Bagchi

Milan K Bagchi

Molecular & Integrative Physiology

Steroid Hormone Regulated Gene Networks Controlling Reproduction and Early Development; Crosstalk of Steroid and Growth Factor Signaling in Breast Cancer; Epigenetic Basis of Endometrial Cancer

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524 Burrill Hall (Administrative Office)
534 Burrill Hall (Research Office)
Office: (217) 244-5054
Lab: (217) 333-7920/3-7697
Fax: (217) 333-1133

Benita S Katzenellenbogen

Benita S Katzenellenbogen

Molecular & Integrative Physiology

Regulation of gene expression, signal transduction, and cell proliferation and phenotypic properties by hormones and growth factors; functional analyses of nuclear hormone receptors and their genome-wide activities; mechanisms of hormone and antihormone action in normal and cancer cells; biomarker discovery and cellular changes underlying resistance to therapeutic agents in breast cancer.

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294 Burrill Hall
Office: (217) 333-9769
Fax: (217) 244-9906

Victor D Ramirez

Victor D Ramirez

Molecular & Integrative Physiology

Molecular Neuroendocrinology

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482 Burrill Hall
Office: (217) 333-1293
Fax: (217) 333-1133

Raven H Huang

Raven H Huang

Biochemistry

Functional and structural characterization of protein enzymes involved in RNA modification and editing, site-specific RNA cleavage, and RNA repair.

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411 Roger Adams Lab
Office: (217) 333-3967
Fax: (217) 244-5858

James A Imlay

James A Imlay

Microbology

Molecular mechanisms of oxidative damage; cellular defenses against oxidants; obligate anaerobiosis

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B303 CLSL
Office: (217) 333-5812
Lab: (217) 244-3462
Fax: (217) 244-6697

Susan  A Martinis

Susan A Martinis

Biochemistry

RNA structure and function, RNA-protein interactions,| chemical mechanisms of biological reactions, protein synthesis, tRNA synthetases

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401A Roger Adams Lab
Office: (217) 244-2405
Lab: (217) 333-4936
Fax: (217) 244-5858

James "Jim" H. Morrissey

James "Jim" H. Morrissey

Biochemistry

Protein-phospholipid interactions; regulation of protease cascades; blood clotting; polyphosphate

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323 Roger Adams Lab (office)
Office: (217) 265-4036
Lab: (217) 265-5424
Fax: (217) 265-5290

Peter A B Orlean

Peter A B Orlean

Microbology

Mechanism of polysaccharide synthesis

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B213 Chemical and Life Sciences Laboratory
601 S. Goodwin Ave.
Urbana, IL 61801
Office: (217) 333-4139

Brenda  Anne Wilson

Brenda Anne Wilson

Microbology

Bacterial protein toxins, their interaction with host cells, their effects on intracellular signal transduction, and development of novel alternative anti-toxin therapeutics; human and nonhuman primate vaginal and gut microbial ecosystems (microbiomes) and their role in health and disease

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B209 CLSL
Office: (217) 244-9631
Lab: (217) 265-8260
Fax: (217) 244-6697

Steven  R Blanke

Steven R Blanke

Microbology

Infection Biology and Cancer, Host-pathogen Interactions, Bacterial Pathogenesis, Bacterial Toxins

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B103 CLSL
Office: (217) 244-2412
Lab: (217) 333-6302

Stephen K Farrand

Stephen K Farrand

Microbology

Molecular biology of the Agrobacterium-plant interaction

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B103 CLSL
Office: (217) 333-1524
Lab: (217) 244-3229

Jeffrey F Gardner

Jeffrey F Gardner

Microbology

Mechanism of site-specific recombination by bacteriophages and conjugative transposons; mechanisms of protein recognition of DNA

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B103 CLSL
Office: (217) 333-7287
Lab: (217) 333-7289

James M Slauch

James M Slauch

Microbology

Molecular mechanisms of Salmonella pathogenesis

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B203 CLSL
Office: (217) 244-1956
Lab: (217) 244-7846
Fax: (217) 244-6697

Cari Vanderpool

Cari Vanderpool

Microbology

Regulation of Bacterial Stress Responses

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C226 CLSL
Office: (217) 333-7033

Brian C Freeman

Brian C Freeman

Cell & Developmental Biology

Hsp90 Chaperone System; Chromatin Landmarks; Gene Regulation; Telomere Biology

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B605 CLSL
Office: (217) 244-2662
Lab: (217) 244-1065

Kurt E Kwast

Kurt E Kwast

Molecular & Integrative Physiology

Oxygen sensing, transcriptional regulation of oxygen-responsive genes, physiological genomics of oxygen regulation.

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186 Burrill Hall
Office: (217) 244-3122
Lab: (217) 244-4588
Fax: (217) 333-1133

Richard I Tapping

Richard I Tapping

Microbology

Regulation of B cell responses by Toll-like receptors; implications for autoimmune disease.

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325 Burrill Hall
407 S. Goodwin Ave.
Urbana, IL 61801
Office: (217) 244-7940
Lab: (217) 333-2203
Fax: (217) 244-6697

Thomas E. Kehl-Fie

Thomas E. Kehl-Fie

Microbology

Impact of host-imposed metal starvation on Staphylococcus aureus and bacterial mechanisms of resistance

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CLSL B401
Office: (217) 244-5471
Fax: (217) 244-6697

Joanna  L. Shisler

Joanna L. Shisler

Microbology

Immune evasion strategies of viruses; host-pathogen interactions; molecular disinfection of viruses; vaccine development

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331 Burrill Hall
Office: (217) 265-6450
Lab: (217) 333-6140

Philip M Best

Philip M Best

Molecular & Integrative Physiology

Calcium channels in the heart: structure, function and regulation

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393 Burrill Hall
Office: (217) 333-8176
Lab: (217) 244-2940
Fax: (217) 333-1133

Albert S Feng

Albert S Feng

Molecular & Integrative Physiology

Neural basis of sound pattern recognition

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2355 Beckman Institute
Office: (217) 244-1951
Lab: (217) 333-7071
Fax: (217) 244-5180

Rutilio "Rudy" A Fratti

Rutilio "Rudy" A Fratti

Biochemistry

Membrane Microdomain Assembly and Membrane Fusion

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490A Roger Adams Lab
Office: (217) 244-5513
Fax: (217) 244-5858

Bruce W Fouke

Bruce W Fouke

Microbology

Does microbial metabolic activity, macromolecular chemistry and extracellular polymeric substance (EPS) production cause disease in coral reef ecosystems and catalyze CaCO3 mineral precipitation in hot springs and caves?

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Institute for Genomic Biology Rm 3406
University of Illinois Urbana-Champaign
1206 W. Gregory Drive
Urbana, IL 61801
Office: (217) 244-5431

David M Kranz

David M Kranz

Biochemistry

Structure, Function, and Engineering of T Cell Receptors; Molecular Basis of Immune Recognition by T Cells; Tumor Targeting with T Cells; Engineering Protein Therapeutics

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352C Burrill Hall
Office: (217) 244-2821
Lab: (217) 244-2823
Fax: (217) 244-5858

Ed Roy

Ed Roy

Molecular & Integrative Physiology

Immunotherapy

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336A Burrill Hall
Office: (217) 333-3375

Stephanie Ceman

Stephanie Ceman

Cell & Developmental Biology

Molecular basis of disease, post-translational modifications, regulation of RNA expression, RNA-protein interactions

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423 Medical Sciences Building
Office: (217) 244-6793
Lab: (217) 244-6749
Fax: (217) 244-1648

Jonathan V Sweedler

Jonathan V Sweedler

Molecular & Integrative Physiology

Novel neurochemistry and the function of cell-to-cell signaling molecules on neuronal network activity

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Lyne Levesque

Lyne Levesque

Cell & Developmental Biology

Ins and outs of nucleocytoplasmic transport

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555 Morrill Hall
Office: (217) 333-7565
Lab: (217) 244-3148
Fax: (217) 244-1648

K V Prasanth

K V Prasanth

Cell & Developmental Biology

long noncoding RNA; Gene regulation; Nuclear domain & structure

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C426 CLSL
Office: (217) 244-7832
Lab: (217) 244-7895
Fax: (217) 244-1648

David H Rivier

David H Rivier

Cell & Developmental Biology

Regulation of chromosomal DNA replication; structure of chromosomal origins; relationship between DNA replication and stable, heritable transcription states (position effects); yeast molecular genetics

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C422 CLSL
Office: (217) 244-0060
Lab: (217) 244-0830
Fax: (217) 244-1648

David S. McPheeters

David S. McPheeters

Biochemistry

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204 Medical Sciences Building, MC-714
506 South Mathews Ave
Urbana, IL 61801
Office: (217) 300-2152
Fax: (217) 244-8576

Archaea

Bioenergetics and Photosynthesis

Biofuels

Bioinformatics

Jeffrey Haas

Cell-Cell Interactions

Cell-Matrix Interactions

Chromatin Structure

Computational Biology

Cytoskeleton

Development

DNA Biology

Drug Discovery

Endocrinology

Enzymology

Genetics

Genomics

Glycobiology

Jeffrey Haas

Host-Pathogen Interactions

Imaging

Ion Channels

Learning and Memory

Membrane Biology

Metabolic Regulation

Microbial Ecology

Microbial Physiology

Molecular Evolution

Molecular Immunology

Neurobiology

Pattern Formation

Protein Dynamics

Protein Structure

Protein Synthesis

Protein-Nucleic Acid Interactions

Proteomics

Receptor Biochemistry

Regulation of Gene Expression

Reproductive Biology

RNA Biology

Sensory Processing

Signal Transduction

Toxins

Virology