News Archive – 2014

Professor Phillip Newmark elected Fellow of the American Association for the Advancement of Science (AAAS).

The Department of Cell and Developmental Biology is proud to announce Dr. Phil Newmak’s fellowship with the AAAS, a prestigious scientific society composed of those who have made outstanding contributions to their field.

December 18, 2014


Professor Phillip Newmark elected as a fellow of the American Association for the Advancement of Science (AAAS)

The School of Molecular and Cellular Biology and the Department of Cell and Developmental Biology are proud to announce Dr. Phil Newmak’s fellowship with the AAAS, a prestigious scientific society composed of those who...

December 18, 2014


Jongsook Kim Kemper’s lab discovers that elevated acetylation of FXR in obesity promotes hepatic inflammation, published in the EMBO Journal

Associate Professor of Molecular and Integrative Physiology, Jongsook Kim Kemper, post-doctoral researcher, Dong-Hyun Kim, and their colleagues discovered that the function of a key metabolic transcriptional regulator, FXR, is modulated by...

December 09, 2014


Jongsook Kim Kemper’s lab discovers that elevated acetylation of FXR in obesity promotes hepatic inflammation, published in the EMBO Journal

Associate Professor of Molecular and Integrative Physiology, Jongsook Kim Kemper, post-doctoral researcher, Dong-Hyun Kim, and their colleagues discovered that the function of a key metabolic transcriptional regulator, FXR, is modulated by...

December 09, 2014


Team discovers how microbes build a powerful antibiotic

From left, University of Illinois graduate research assistant Manuel A. Ortega, chemistry professor Wilfred van der Donk, graduate student Yue Hao, biochemistry professor Satish Nair, and postdoctoral researcher Mark Walker solved a decades-old mystery into how a broad class of natural antibiotics are...

December 05, 2014


Professor Tajkhorshid Awarded Supercomputing Capacity at DOE National Laboratory

Large-scale simulations will develop a greater understanding of cellular membrane transporters, which could allow drug developers to design more targeted drugs for major pathophysiological conditions such as psychological disorders, cancer, and multi-drug resistance.

November 19, 2014


Professor Tajkhorshid Awarded Supercomputing Capacity at DOE National Laboratory

Large-scale simulations will develop a greater understanding of cellular membrane transporters, which could allow drug developers to design more targeted drugs for major pathophysiological conditions such as psychological disorders, cancer, and multi-drug resistance.

November 19, 2014


Professor Jongsook Kim Kemper and collaborators discover FXR and CREB as key physiological regulators of autophagy, published in the journal Nature.

Autophagy or “self-eating” is the breakdown and recycling of cellular components and is essential for cellular survival under starvation but must be suppressed upon feeding. Acute regulation of...

November 13, 2014


Professor Jongsook Kim Kemper and collaborators discover FXR and CREB as key physiological regulators of autophagy, published in the journal Nature.

Autophagy or “self-eating” is the breakdown and recycling of cellular components and is essential for cellular survival under starvation but must be suppressed upon feeding. Acute regulation of...

November 13, 2014


Scientists engineer human T cell receptors against cancer antigens

Graduate student Sheena Smith and Professor David Kranz of the Department of Biochemistry have developed an approach to discover T cell receptors that could be therapeutically useful against different cancers. In collaboration with graduate students Yuhang Wang and Javier Baylor and Professor...

November 07, 2014


Scientists engineer human T cell receptors against cancer antigens

Graduate student Sheena Smith and Professor David Kranz of the Department of Biochemistry have developed an approach to discover T cell receptors that could be therapeutically useful against different cancers. In collaboration with graduate students Yuhang Wang and Javier Baylor and Professor...

November 07, 2014


Scientists discover a new role for estrogen in the pathology of breast cancer

Biochemistry professor David Shapiro (center), M.D.-Ph.D student Neal Andruska (left), graduate student Xiaobin Zheng and their colleagues discovered a new mechanism by which estrogen contributes to the pathology of breast cancer. The findings are published in the journal...

October 02, 2014


Scientists discover a new role for estrogen in the pathology of breast cancer

Biochemistry professor David Shapiro (center), M.D.-Ph.D student Neal Andruska (left), graduate student Xiaobin Zheng and their colleagues discovered a new mechanism by which estrogen contributes to the pathology of breast cancer. The findings are published in the journal...

October 02, 2014


CD2AP is necessary to stabilize the actin polymer associated with cadherins at adhesive cell junctions

By capping the tips of actin filaments, CD2AP reinforces the junctions between epithelial cells, Tang and Brieher show.

September 08, 2014


Phosphorylation of HP1α regulates mitosis in human cells

The Prasanth laboratory, with post-doctoral associate and lead author, Arindam Chakraborty, have shown that mammalian NDR kinase mediates the hinge specific phosphorylation of HP1α preferentially at the G2/M phase of the cell cycle in Nature Communications.

September 03, 2014


NSF awards BRAIN EAGER grant to team led by Martha Gillette

A Team led by Martha Gillette, professor of Cell and Developmental Biology, Molecular and Integrative Physiology, Neuroscience and Bioengineering, has been awarded a BRAIN EAGER grant from NSF for a project titled “Multiscale dynamics and emergent properties of suprachiasmatic circuits...

August 26, 2014


A radical reaction utilizes two of the most popular cofactors for tRNA modification

In the latest issue of Nature Chemical Biology, biochemistry graduate student Kiruthika Selvadurai and associate professor Raven Huang reported their findings that the chemistry of eukaryotic tRNA modification at the “wobble” position is performed entirely by a single...

August 25, 2014


A radical reaction utilizes two of the most popular cofactors for tRNA modification

In the latest issue of Nature Chemical Biology, biochemistry graduate student Kiruthika Selvadurai and associate professor Raven Huang reported their findings that the chemistry of eukaryotic tRNA modification at the “wobble” position is performed entirely by a single...

August 25, 2014


Biochemistry notes the passing of noted former faculty member, J. Woodland "Woody" Hastings

Dr. Hastings was a biochemistry faculty member at the University of Illinois from 1957 to 1966. His groundbreaking research focused on communication among bacteria. An endowed chair his name, donated by George and Tamara Mitchell, is currently held...

August 22, 2014


How Heat-Loving Organisms Are Helping Advance Medicine

One of the fascinating things about this world are organisms that live (and thrive) in extreme conditions. Dr. Robert Gennis leads an NIH-funded team that is studying membrane protein from thermophiles.

August 20, 2014


Dr. Claudio Grosman named Romano Professorial Scholar

Dr. Claudio Grosman has been named a Richard and Margaret Romano Professorial Scholar. The three-year appointment recognizes outstanding research achievement and campus leadership through the College of Liberal Arts and Sciences.

August 06, 2014


Side-chain rotamers make a difference

Third-year Biophysics graduate student Tyler Harpole and Professor of Molecular and Integrative Physiology, Biophysics and Neuroscience, Claudio Grosman, have used molecular dynamics and Brownian dynamics computer simulations to test a novel hypothesis as to how the nicotinic acetylcholine receptor controls the rate at which cations enter...

July 29, 2014


Side-chain rotamers make a difference

Third-year Biophysics graduate student Tyler Harpole and Professor of Molecular and Integrative Physiology, Biophysics and Neuroscience, Claudio Grosman, have used molecular dynamics and Brownian dynamics computer simulations to test a novel hypothesis as to how the nicotinic acetylcholine receptor controls the rate at which cations enter...

July 22, 2014


Microbial Diversity – A Tribute to the Life and Work of Abigail Salyers

Symposium: Saturday, November 8, 2014 Hosted by the Department of Microbiology, University of Illinois at Urbana-Champaign.

June 24, 2014


Microbial Diversity – A Tribute to the Life and Work of Abigail Salyers

Symposium: Saturday, November 8, 2014 Hosted by the Department of Microbiology, University of Illinois at Urbana-Champaign.

June 24, 2014


Kalsotra Awarded Nationally Competitive March of Dimes Research Grant

Assistant professor of biochemistry and medical biochemistry, Auinash Kalsotra, has been awarded the Basil O’Conner Starter Scholar Research Award from the March of Dimes.

February 19, 2014


MicroRNA misregulation in muscular dystrophy

Assistant Professor of Biochemistry, Auinash Kalsotra, and colleagues have discovered the process by which myotonic dystrophy affects activity of the small bits of genetic material called microRNAs in the heart.

January 24, 2014