Highlights Archive

2013

XPLN: a novel regulator of mTORC2 in cell survival and differentiation

The protein kinase mammalian target of rapamycin (mTOR) is a master regulator of cell growth, survival, differentiation, and metabolism.

Read the whole story...


It takes a(n academic) village to determine an enzyme's function

Professor of Microbiology John Cronan, Professor of Biochemistry John Gerlt and Professor of Chemistry Jonathan Sweedler, along with colleagues from two other institutions, teamed up to discover the role of an enzyme known as HpbD in its bacterial host, Pelagibaca bermudensis.

Read the whole story...


Procotyla300

How to Grow a New Head

Professor of Cell and Developmental Biology and Howard Hughes Medical Institute Investigator Phillip Newmark and his colleague James Sikes have found an answer to a vexing biological riddle.

Read the whole story...


Emad300

Team Discovers How Aquaporins Admit Water While Excluding Protons

Associate Professor of Biochemistry Emad Tajkhorshid and colleagues have discovered a new mechanism by which water channel proteins in cell membranes allow water molecules to flow easily while keeping protons out. The research appears in the journal Science.

Read the whole story...


Small RNA-mediated activation of sugar phosphatase mRNA regulates glucose homeostasis

Assistant Professor of Microbiology Carin Vanderpool and colleagues have identified the conserved haloacid dehalogenase (HAD)-like enzyme YigL as the previously hypothesized phosphatase for detoxification of phosphosugars, and reveal that its synthesis is activated by an Hfq-dependent small RNA in Salmonella typhimurium.

Read the whole story...


20130305newmark

Study reveals stem cells in a human parasite

Read the whole story...