School of MCB COVID-19 Information

Pamela P. Martinez

Pamela P. Martinez

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Assistant Professor of Microbiology

Research Topics

Computational Biology, Host-Pathogen Interactions, Microbial Ecology

Disease Research Interests

Infectious Diseases

In most pathogens, epidemiological and evolutionary processes occur on similar time scales due to the large population sizes and short generation times. This makes infectious diseases amenable to study and the interplay of their ecology and evolution particularly relevant for both fundamental biology and applied public health. However, temporal and spatial changes in infectious disease dynamics are difficult to anticipate due to the effects of environmental drivers on the transmission of pathogens and the complex diversity that these microorganisms exhibit. To address these challenges, my research on the ecology and evolution of infectious diseases focuses on the following general questions: How do environmental factors, especially ones related to climate, shape the population dynamics of infectious diseases in space and time? and How does pathogen diversity interact and interfere with public health interventions?

Representative Publications

Rodo, X., Martinez, P.P., Siraj, A., Pascual, M., Malaria trends in Ethiopian highlands track the 2000 slowdown in global temperatures. Under Review at Nature Communications.

Azarian, T*., Martinez, P.P.*, Arnold, B.J., Grant, L.R., Corander, J., Fraser, C., Croucher, N.J., Ham-mitt, L.L., Reid, R., Santosham, M. and Weatherholtz, R.C., Bentley, S.D., O’Brien K.L., Lipsitch,M., Hanage, W. P. Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae. Accepted, Plos Biology.

Martinez, P.P.*, Mahmud A.S.*, Yunus, M., Faruque, A.S.G., Ahmed T., Pascual, M., Buckee, C.O.,2019. Tube Well Use as Protection Against Rotavirus Infection During the Monsoons in an Urban Setting, The Journal of Infectious Diseases, jiz436.

Martinez, P.P., King, A.A., Yunus, M., Faruque, A.S.G., Pascual, M., 2016. Differential and enhanced response to climate forcing in diarrheal disease due to rotavirus across a megacity of the developing world. Proceedings of the National Academy of Sciences, 113(15), pp.4092-4097.