Satish Nair Published in PNAS

Associate Professor of Biochemistry Satish Nair and Biochemistry Affiliate Wilfred van der Donk are corresponding authors on "Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis," appearing in the Proceedings of the National Academy of Sciences (PNAS).

Associate Professor of Biochemistry Satish Nair and Biochemistry Affiliate Wilfred van der Donk are corresponding authors on "Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis," appearing in the Proceedings of the National Academy of Sciences (PNAS). Former Biochemistry graduate student Brian Bae also contributed to the research.

According to Professor and Head of Biochemistry Susan Martinis, the study "reports a beautiful interdisciplinary investigation that combines X-ray crystallography and biochemistry to identify the substrate scope of an important enzyme in a phosphonate biosynthetic pathway that has implications for antibiotic development."

PNAS

October 27, 2010 All News