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Welcome to Molecular and Integrative Physiology

In this post-genomic era, physiology is uniquely poised at the nexus between molecular function and whole animal integration with the goal of understanding how the functions of thousands of encoded proteins serve to bring about the highly coordinated behavior of cells and tissues underlying physiological functions in animals and how their dysfunction may lead to disease.  Research and graduate training in the Department of Molecular & Integrative Physiology is focused on understanding the regulation and function of gene products at multiple levels of biological organization, from molecules and macromolecular complexes to cells, tissues, and whole organisms. With the tools of molecular genetics and modern systems biology, physiologists are at the forefront of dramatic advances currently occurring in life and biomedical sciences. Advanced training in molecular and integrative physiology will provide the necessary foundation to prepare for a career in this exciting area of functional biology.

Milan K. Bagchi, Head


MIP News

Side-chain rotamers make a difference

Third-year Biophysics graduate student Tyler Harpole and Professor of Molecular and Integrative Physiology, Biophysics and Neuroscience, Claudio Grosman, have used molecular dynamics and Brownian dynamics computer simulations to test a novel hypothesis as to how the nicotinic acetylcholine receptor controls the rate at which cations enter the cell through the receptor’s transmembrane pore. Read more...

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