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Claudio Grosman.

Welcome to Molecular and Integrative Physiology

In this post-genomic era, physiology is uniquely poised at the nexus between molecular function and whole animal integration with the goal of understanding how the functions of thousands of encoded proteins serve to bring about the highly coordinated behavior of cells and tissues underlying physiological functions in animals and how their dysfunction may lead to disease.  Research and graduate training in the Department of Molecular & Integrative Physiology is focused on understanding the regulation and function of gene products at multiple levels of biological organization, from molecules and macromolecular complexes to cells, tissues, and whole organisms. With the tools of molecular genetics and modern systems biology, physiologists are at the forefront of dramatic advances currently occurring in life and biomedical sciences. Advanced training in molecular and integrative physiology will provide the necessary foundation to prepare for a career in this exciting area of functional biology.

Claudio Grosman, Head


MIP News

ChBE professor Hyunjoon (Joon) Kong recently received two grants from the NSF to fund interdisciplinary research at the Beckman Institute for Advanced Science and Technology, including a look at how neurons and muscle cells communicate with each other and also to develop a drug delivery system for treatment of Alzheimer’s disease. He will be collaborating with Martha Gillette (professor of Cell and Developmental Biology) and Hee Jung Chung (associate professor of Molecular and Integrative Physiology).
In biology, it is generally believed that a protein’s sequence determines its structure, which in turn determines its function. However, in the case of membrane proteins, the reality is more complicated than this simple statement. “In recent years, the importance of a protein’s local environment has been increasingly recognized, but the molecular-level details have not been quite clear”, says Dr. Yuhang (“Steven”) Wang, co-author of a recent paper from the Grosman and Tajkhorshid labs published earlier this month in PNAS.
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