Small RNA-mediated activation of sugar phosphatase mRNA regulates glucose homeostasis

Assistant Professor of Microbiology Carin Vanderpool and colleagues have identified the conserved haloacid dehalogenase (HAD)-like enzyme YigL as the previously hypothesized phosphatase for detoxification of phosphosugars, and reveal that its synthesis is activated by an Hfq-dependent small RNA in Salmonella typhimurium.