The Journal of Molecular Biology covers the following research areas:
	- Biomolecular interactions, signaling networks, systems biology 
- Cell cycle, cell growth, cell differentiation 
- Cell death, autophagy 
- Cell signaling and regulation 
- Chemical biology 
- Computational biology, in combination with experimental studies 
- DNA replication, repair, and recombination 
- Development, regenerative biology, mechanistic and functional studies of stem cells 
- Epigenetics, chromatin structure and function 
- Gene expression 
- Receptors, channels, and transporters 
- Membrane processes 
- Cell surface proteins and cell adhesion 
- Methodological advances, both experimental and theoretical, including databases 
- Microbiology, virology, and interactions with the host or environment 
- Microbiota mechanistic and functional studies 
- Nuclear organization 
- Post-translational modifications, proteomics 
- Processing and function of biologically important macromolecules and complexes 
- Molecular basis of disease 
- RNA processing, structure and functions of non-coding RNAs, transcription 
- Sorting, spatiotemporal organization, trafficking 
- Structural biology 
- Synthetic biology 
- Translation, protein folding, chaperones, protein degradation and quality control