Extension of the Cellular Molecular Chaperone Network

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  The eukaryotic molecular chaperone network is formed by the concerted actions of Hsp90, Hsp70 and their associated cochaperones. Typically, cochaperones had been considered regulatory factors that modulate the ATPase activities of Hsp90 and Hsp70 and also guide these chaperone to distinct...

Phil Newmark appointed as a Romano Scholar

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Associate Professor of Cell and Developmental Biology and Howard Hughes Medical Institute Investigator Phillip Newmark, has been appointed as a Richard and Margaret Romano Professorial Scholar. The appointment is for a three-year term and will provide a discretionary fund of $25,000 per annum to...

Mechanism of Actin Nucleation at Adherens Junctions

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The cells comprising all solid tissues in our bodies are held together by a family of adhesion molecules known as cadherins. A network of intracellular fibers known as actin strengthens the adhesive contact, but the molecular mechanisms connecting actin filaments to cadherins are poorly understood...

Building up actin at adherens junctions

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Assistant Professor of Cell and Developmental Biology William Brieher and Vivan Tang have published "α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction" in the Journal of Cell Biology.

Linking heterochromatin and gene repression

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Assistant Professor of Cell and Developmental Biology Supriya Prasanth is corresponding author on "A BEN-domain-containing protein associates with heterochromatin and represses transcription," published in Journal of Cell Science.