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Researchers find active transporters are universally leaky
Professor of Biochemistry Emad Tajkhorshid and colleagues have discovered that membrane transporters help not just sugars and other specific substrates cross from one side of a cellular membrane to the other—water also comes along for the ride.
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Team finds a new way to inhibit blood clotting and inflammation
Corresponding author Professor of Biochemistry James Morrissey and colleagues have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition...
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Michelle Wegscheid Receives ASM Undergraduate Research Fellowship
The American Society for Microbiology (ASM) has selected Michelle Wegscheid, a senior in the Specialized Curriculum in Biochemistry, as a 2012 award recipient of the ASM Undergraduate Research Fellowship.
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A Gain-of-Function Polymorphism Controlling Complex Traits and Fitness in Nature
Professor of Cell and Developmental Biology and Biochemistry Mary Schuler and colleagues have published a new study in Science.
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Synthesis of Methylphosphonic Acid by Marine Microbes: A Source for Methane in the Aerobic Ocean
Professor of Microbiology William Metcalf is lead author on a new study of ocean methane in Science. Up to 4 percent of the methane on Earth comes from the ocean’s oxygen-rich waters, but scientists have been unable to identify the source of this potent greenhouse gas. Now researchers report that...
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Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair
Associate Professor of Biochemistry Raven Huang and colleagues have published "Molecular basis of bacterial protein Hen1 activating the ligase activity of bacterial protein Pnkp for RNA repair" in the Proceedings of the National Academy of Sciences.
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A protease for 'middle-down' proteomics
Cong Wu, a graduate student in the Department of Biochemistry, is the first author on "A protease for 'middle-down' proteomics" in Nature Methods.
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James H. Morrissey Appointed Roy and Eva Hong Professor of Molecular and Cellular Biology
Professor of Biochemistry James H. Morrissey has been appointed as the Roy and Eva Hong Professor of Molecular and Cellular Biology.
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Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer
Assistant Professor of Biochemistry and Medical Biochemistry at the College of Medicine Lin-Feng Chen is corresponding author on a new study on RUNX3, a tumor suppressor in breast cancer.
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Accelerating Membrane Insertion of Peripheral Proteins with a Novel Membrane Mimetic Model
Emad Tajkhorshid is corresponding author on "Accelerating Membrane Insertion of Peripheral Proteins with a Novel Membrane Mimetic Model," selected as the feature cover article in the May 2 issue of Biophysical Journal.