Team finds mechanism linking key inflammatory marker to cancer

In a new study described in the journal Oncogene, Professor of Biochemistry Lin-Feng Chen and his team reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

Researchers find active transporters are universally leaky

Professor of Biochemistry Emad Tajkhorshid and colleagues have discovered that membrane transporters help not just sugars and other specific substrates cross from one side of a cellular membrane to the other—water also comes along for the ride.

Team finds a new way to inhibit blood clotting and inflammation

Corresponding author Professor of Biochemistry James Morrissey and colleagues have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition...

A protease for 'middle-down' proteomics

Cong Wu, a graduate student in the Department of Biochemistry, is the first author on "A protease for 'middle-down' proteomics" in Nature Methods.