Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides...

Chemists have determined for the first time the crystal structure and unlocked the mechanism of reaction activity of a key component of the monensin enzyme.  “The main finding was the first crystal structure for this family of enzymes,” said...