Institute for Genomic Biology (IGB)

Erik Nelson, professor of molecular and integrative physiology, has won a $4.5 million Era of Hope Scholar Award from the United States Department of Defense Breast Cancer Research Program.This prestigious award supports individuals early in their careers who have demonstrated significant potential...

In breast cancer tumors, a molecule produced when the body breaks down cholesterol hijacks the myeloid immune cells that normally arm T cells to fight cancer, a new study in mice found. Instead, the hijacked myeloid cells disarm the T cells and even tell them to self-destruct.

The National Science Foundation (NSF) announced a five-year, $12.5 million grant to integrate biology to a collaborative team based in the Carl R. Woese Institute for Genomic Biology at the University of Illinois Urbana-Champaign. The new institute, Genomics and Eco-evolution of Multi-scale...

A collaborative effort at the University of Illinois to support COVID-19 testing is winding down, but not before it produced enough materials to support some 200,000 coronavirus tests across the state.

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia. It modifies a patient’s own T-cells by adding a piece of an antibody that recognizes unique features on the surface of cancer cells. In a new study, researchers report that they...

An investigation of two closely related proteins from a pathogenic bacterium has illustrated for the first time how evolution can shape the use of essential metals by enzymes.

Back in early March, when the COVID-19 pandemic began shuttering businesses and schools across the United States, Chris Brooke wondered how he’d teach his classes online. As the virus spread with astonishing speed, however, and it became frighteningly clear that COVID-19 threatened something far...

“Between the realms of agriculture, nature, and humans, the unifying factor is the microbes that exist in each and the specific genes those microbes carry.The IGOH theme at the IGB allows research to be contextualized, and to exist in a space where lab work becomes immediately relevant and...

“Microbes are king of the world. If human beings ceased to exist, microbes wouldn’t even notice [except those in the human microbiome], but if microbes ceased to exist today, human beings would cease to exist tomorrow.”

New research conducted by biochemists at the University of Illinois has determined how damaged liver cells repair and restore themselves through a signal to return to an early stage of postnatal organ development. The findings are reported in the journal Nature Structural & Molecular Biology.