Additional Campus Affiliations
Associate Professor, Bioengineering
Associate Professor, Biomedical and Translational Sciences
Affiliate, Molecular and Integrative Physiology
Associate Professor, Carl R. Woese Institute for Genomic Biology
Recent Publications
Shirguppe, S., Gapinske, M., Swami, D., Shenouda, K., Miskalis, A., Gosstola, N., Del Bosque Siller, D., Guerra, I., Acharya, P., Joulani, D., Szkwarek, M. G., Nambiar, A., Bhattacharjee, A., Dangi, A. S., Odle, N., Nathan, G. E., Elias, G., Stilger, M., Winter, J., ... Perez-Pinera, P. (2026). In vivo CRISPR base editing for treatment of Huntington’s disease. Nature biomedical engineering. Advance online publication. https://doi.org/10.1038/s41551-026-01747-y
Song, Y. J., Shinn, M. K., Bangru, S., Wang, Y., Sun, Q., Hao, Q., Chaturvedi, P., Freier, S. M., Perez-Pinera, P., Nelson, E. R., Belmont, A. S., Guttman, M., Prasanth, S. G., Kalsotra, A., Pappu, R. V., & Prasanth, K. V. (2026). LncRNA-splicing factor condensates regulate hypoxia-responsive pre-mRNA processing near nuclear speckles. Molecular cell, 86(6), 1061-1080.e10. https://doi.org/10.1016/j.molcel.2026.02.014
Guerra, I., Jensen, K., & Perez-Pinera, P. (2025). Implementation of an Undergraduate Laboratory-Based Mammalian Genome Editing Course. CRISPR Journal, 8(5), 366-374. https://doi.org/10.1089/crispr.2025.0017
Quijano, E., Martinez-Saucedo, D., Ianniello, Z., Pinto-Medici, N., Rackear, M., Chen, H., Lola-Pereira, L., Liu, Y., Hegan, D., Shan, X., Tseng, R., Yugawa, D., Chowdhury, S., Khang, M., Singh, J. P., Abdullah, R., Azhir, P., Kashima, S., Woods, W. S., ... Glazer, P. M. (2025). Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer. Science Translational Medicine, 17(807), Article eadk1868. https://doi.org/10.1126/scitranslmed.adk1868
Miskalis, A., Shirguppe, S., Winter, J., Elias, G., Swami, D., Nambiar, A., Stilger, M., Woods, W. S., Gosstola, N., Gapinske, M., Zeballos, A., Moore, H., Maslov, S., Gaj, T., & Perez-Pinera, P. (2024). SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping. Nature communications, 15(1), Article 10354. https://doi.org/10.1038/s41467-024-54529-y