Samy Meroueh

Landgraf, A. D., Brenner, R., Ghozayel, M. K., Bum-Erdene, K., Gonzalez-Gutierrez, G., & Meroueh, S. O. (2025). Small-Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation. ChemMedChem, 20(12), Article e202400624. https://doi.org/10.1002/cmdc.202400624

Brenner, R. J., Landgraf, A. D., Bum-Erdene, K., Gonzalez-Gutierrez, G., & Meroueh, S. O. (2023). Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling. Biochemistry, 62(22), 3206-3213. https://doi.org/10.1021/acs.biochem.3c00378

Bum-Erdene, K., Ghozayel, M. K., Zhang, M. J., Gonzalez-Gutierrez, G., & Meroueh, S. O. (2023). Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEAD·YAP1 interaction. RSC Medicinal Chemistry, 14(9), 1803-1816. https://doi.org/10.1039/d3md00264k

Bum-Erdene, K., Yeh, I. J., Gonzalez-Gutierrez, G., Ghozayel, M. K., Pollok, K., & Meroueh, S. O. (2023). Small-Molecule Cyanamide Pan-TEAD·YAP1 Covalent Antagonists. Journal of Medicinal Chemistry, 66(1), 266-284. https://doi.org/10.1021/acs.jmedchem.2c01189

Hussain, M. S., Liu, D., Alilain, W. J., & Meroueh, S. O. (2023). Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors. ACS Chemical Neuroscience, 14(14), 2509-2516. https://doi.org/10.1021/acschemneuro.3c00154

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