Team discovers how bacteria resist a 'Trojan horse' antibiotic

A new study led by Associate Professor of Biochemistry Satish Nair describes how bacteria use a previously unknown means to defeat an antibiotic.

A new study led by Associate Professor of Biochemistry Satish Nair describes how bacteria use a previously unknown means to defeat an antibiotic. The researchers found that the bacteria have modified a common “housekeeping” enzyme in a way that enables the enzyme to recognize and disarm the antibiotic.

"Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7" appears in PNAS.