Immunity publishes papers focused on advances in immunology research. Subjects include immune cell development and senescence, signal transduction, gene regulation, innate and adaptive immunity, autoimmunity, infectious disease, allergy and asthma, transplantation, and tumor immunology

 

Machine-learning model can distinguish antibody targets

Different antibodies (green, aqua, pink) attack different parts of the SARS-CoV-2 viral particle (yellow/orange sphere). The virus’s spike proteins (purple) are a key antibody target, with some antibodies attaching to the top (darker purple) and others to the stem (paler zone). Graphic by Yiquan Wang
A new study from the School of Molecular & Cellular Biology shows that it is possible to use the genetic sequences of a person’s antibodies to predict what pathogens those antibodies will target. Reported in the journal Immunity, the new approach successfully differentiates between antibodies...