Science Translational Medicine

Science Translational Medicine publishes weekly peer-reviewed articles that focus on the latest research advances from biomedical, translational, and clinical researchers from all established an emerging disciplines relevant to medicine. 

 

Researchers discovered a small molecule, ErSO, that eradicates breast cancers in mice by targeting a pathway that protects cancer cells. Photo by L. Brian Stauffer

New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.
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New drug compounds show promise against endometriosis

An interdisciplinary research team, including molecular and integrative physiology professors Benita Katzenellenbogen and Milan Bagchi, has developed a new approach to treating endometriosis. Their research appears in Science Translational Medicine.