Unraveling mechanisms of FXR in protection against liver diseases

Obesity is rising in prevalence and poses a major concern for the health of our general population. Currently affecting over one-third of the population of the United States, obesity is often comorbid with other diseases, such as diabetes, fatty liver disease, cardiovascular disease, and some...

New NIH grant to fund U of I research on Fragile X Syndrome

Recent clinical trials involving Fragile X Syndrome (FXS), a genetic disorder that causes mild to severe intellectual disability, indicate that potential drug treatments are not as effective as researchers initially hoped. This lack of therapeutic potential suggests there are some gaps in our...

What is the new variant of coronavirus in the UK?

New mutations to the coronavirus that causes COVID-19 are emerging, including one in the United Kingdom with higher infection rates that has sparked new travel bans. Erik Procko, a professor of biochemistry at the University of Illinois Urbana-Champaign, has been studying mutations in the spike...

Stadtmueller Lab determines the structure of our predominant mucosal antibody

It has been over 60 years since scientists first identified the molecule that we know today as immunoglobulin (Ig) A. IgA is the predominant class of antibody found in human mucus where it is known as secretory (S) IgA. SIgA functions to bind microbes in extracellular regions such as the gut and...

Researchers uncover the role of a noncoding RNA in cell proliferation

Kannanganattu V. Prasanth, professor of cell and developmental biology, and members of his lab investigate the regulation of gene expression and RNA biology with a focus on cancer. In a new article published in eLife, “The S-phase-induced lncRNA promotes cell proliferation by controlling YAP1/Hippo...