Scientists engineer human T cell receptors against cancer antigens

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Graduate student Sheena Smith and Professor David Kranz of the Department of Biochemistry have developed an approach to discover T cell receptors that could be therapeutically useful against different cancers. In collaboration with graduate students Yuhang Wang and Javier Baylor and Professor Emad...

Phosphorylation of HP1α regulates mitosis in human cells

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The Prasanth laboratory, with post-doctoral associate and lead author, Arindam Chakraborty, have shown that mammalian NDR kinase mediates the hinge specific phosphorylation of HP1α preferentially at the G2/M phase of the cell cycle in Nature Communications.

NSF awards BRAIN EAGER grant to team led by Martha Gillette

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A Team led by Martha Gillette, professor of Cell and Developmental Biology, Molecular and Integrative Physiology, Neuroscience and Bioengineering, has been awarded a BRAIN EAGER grant from NSF for a project titled “Multiscale dynamics and emergent properties of suprachiasmatic circuits in real time...

Dr. Claudio Grosman named Romano Professorial Scholar

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Dr. Claudio Grosman has been named a Richard and Margaret Romano Professorial Scholar. The three-year appointment recognizes outstanding research achievement and campus leadership through the College of Liberal Arts and Sciences.

Side-chain rotamers make a difference

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Third-year Biophysics graduate student Tyler Harpole and Professor of Molecular and Integrative Physiology, Biophysics and Neuroscience, Claudio Grosman, have used molecular dynamics and Brownian dynamics computer simulations to test a novel hypothesis as to how the nicotinic acetylcholine receptor...

MicroRNA misregulation in muscular dystrophy

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Assistant Professor of Biochemistry, Auinash Kalsotra, and colleagues have discovered the process by which myotonic dystrophy affects activity of the small bits of genetic material called microRNAs in the heart.