MCB

Team finds a new way to inhibit blood clotting and inflammation

2012-11-05

Corresponding author Professor of Biochemistry James Morrissey and colleagues have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition...

Using planarian flatworms to understand organ regeneration

2012-10-23

In a new study published in the October 16 issue of Developmental Cell, corresponding author Professor of Cell and Developmental Biology and Howard Hughes Medical Institute Investigator Phillip Newmark and colleagues report the identification of genes that control growth and regeneration of the...

The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors

2012-10-14

In a new finding published in Nature Chemical Biology, Research Scientist Gisela Cymes and Associate Professor of Molecular and Integrative Physiology, Biophysics, and Neuroscience Claudio Grosman applied single-molecule electrophysiology to elucidate the properties of the ring of acidic side...

The p23 Molecular Chaperone and GCN5 Acetylase Jointly Modulate Protein-DNA Dynamics and Open Chromatin Status

2012-10-03

Associate Professor of Cell and Developmental Biology and Alexander von Humboldt Scholar Brian Freeman and colleagues have published "The p23 Molecular Chaperone and GCN5 Acetylase Jointly Modulate Protein-DNA Dynamics and Open Chromatin Status" in Molecular Cell.

The p23 Molecular Chaperone and GCN5 Acetylase Jointly Modulate Protein-DNA Dynamics

2012-10-04

An in-depth understanding of any machine requires classification of the individual parts, knowledge on how the components connect, and recognition of the mechanisms propelling the assembled pieces into a running unit. As biologist we have made admirable progress in naming the numerous physical...

IN OBESITY, A MICRO-RNA CAUSES METABOLIC PROBLEMS

2012-09-20

A tight shot of a microscope with a soft orange gradient layer.

A team including corresponding author Associate Professor of Molecular and Integrative Physiology Jongsook Kim Kemper has identified a key molecular player in a chain of events in the body that can lead to fatty liver disease, Type II diabetes and other metabolic abnormalities associated with...

Michelle Wegscheid Receives ASM Undergraduate Research Fellowship

2012-09-20

Photo of two rows of pink test tubes in an orange test tube holder.

The American Society for Microbiology (ASM) has selected Michelle Wegscheid, a senior in the Specialized Curriculum in Biochemistry, as a 2012 award recipient of the ASM Undergraduate Research Fellowship.

Phillip Newmark named University Scholar

2012-09-11

Professor of Cell and Developmental Biology and Howard Hughes Medical Investigator Phillip Newmark is among seven university faculty named a University Scholar.

Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons

2012-09-02

Although cellular metabolic (redox) state has long been associated with a housekeeping role, recent research from a team lead by Martha Gillette, and including the Lee Cox and Jonathan Sweedler groups, provides new insights on cellular redox states, linking them to the intrinsic daily (circadian)...

A Gain-of-Function Polymorphism Controlling Complex Traits and Fitness in Nature

2012-08-30

Professor of Cell and Developmental Biology and Biochemistry Mary Schuler and colleagues have published a new study in Science.

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