MCB

Mechanism of Actin Nucleation at Adherens Junctions

2012-03-27

The cells comprising all solid tissues in our bodies are held together by a family of adhesion molecules known as cadherins. A network of intracellular fibers known as actin strengthens the adhesive contact, but the molecular mechanisms connecting actin filaments to cadherins are poorly understood...

Mutations that stabilize the open state of the <em>Erwinia chrisanthemi</em> ligand-gated ion channel fail to change the conformation of the pore domain in crystals

2012-04-02

Corresponding author Professor of Molecular and Integrative Physiology Claudio Grosman, Associate Professor of Biochemistry Satish Nair, and colleagues have published new work in PNAS.

Phosphodiesterases coordinate cAMP propagation induced by two stimulatory G protein-coupled receptors in hearts

2012-04-09

In a new study, Assistant Professor of Molecular and Integrative Physiology Kevin Xiang and colleagues show that the PGE2 stimulation attenuates the adrenergic-induced cardiac contractile response in animal hearts.

Rachel Smith-Bolton Receives Carver Charitable Trust Award

2012-04-03

Assistant Professor of Cell and Developmental Biology Rachel Smith-Bolton has been awarded the highly competitive 3-year Carver Young Investigator Award. The award pays $300,000 over three years.

Team discovers how bacteria resist a 'Trojan horse' antibiotic

2012-03-20

A new study led by Associate Professor of Biochemistry Satish Nair describes how bacteria use a previously unknown means to defeat an antibiotic.

Molecular Determinants of Scouting Behavior in Honey Bees

2012-03-14

There is novelty-seeking behavior, across different contexts, among honey bees in their tendency to scout for food sources and nest sites.

Msx Homeobox Genes Critically Regulate Embryo Implantation

2012-02-28

A unique signaling network regulated by the homeobox transcription factors MSX1 and MSX2 in the mouse uterus critically controls female fertility.

Team Discovers Microbes Speciating

2012-02-21

Rachel Whitaker sits at desk, smiling for camera.

Not that long ago in a hot spring in Kamchatka, Russia, two groups of genetically indistinguishable microbes parted ways. They began evolving into different species – despite the fact that they still encountered one another in their acidic, boiling habitat and even exchanged some genes from time to...

Phylogeny and beyond: Scientific, historical, and conceptual significance of the first tree of life

2012-01-31

A fundamental breakthrough in biological science occurred in 1977, and most biologists did not notice: a paper by Professor of Microbiology Carl Woese that compared sequence snippets derived from small subunit rRNAs of different organisms.

Attack or retreat? Circuit links hunger and pursuit in sea slug brain

2012-01-31

In a new study, Professor of Molecular and Integrative Physiology Rhanor Gillette reports on a circuit in the brain of the sea slug Pleurobranchaea.

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