The infinitely complex workings of the human brain have intrigued researchers for centuries. Our understanding of its workings have been limited, not by our curiosity, but by our tools. Now, with the growth of new molecular biology and genomics approaches, big data, and engineering advances that...
Professor Satish Nair of the Department of Biochemistry has been appointed Director of the Center for Biophysics and Quantitative Biology. Professor Nair has been serving as Interim Director since November 2015. Professor Martha Gillette of the Department of Cell and Developmental Biology has been...
G protein-coupled receptors (GPCRs) are the largest and most versatile family of cell-surface receptors. They play critical roles in various cellular and physiological systems and have emerged as a leading group of therapeutic targets. Due to their structural and functional conservation across...
In a study published in PLoS Genetics, graduate student Harini Iyer and colleagues show that the transcription factor Nuclear Factor Y-B (NF-YB) is required for SSC proliferation in planarians as well as in Schistosoma mansoni, a parasitic flatworm related to the free-living planarian and a...
Gillette, professor of cell and developmental biology, and colleagues will collaborate on various projects involving innovative single cell analysis in brain and the creation of biological machines in hopes of creating new diagnostic and therapeutic tools.
Professor of Cell and Developmental Biology and Principal Investigator Andrew Belmont from the University of Illinois heads a team of Investigators that has been awarded an $8M grant over five years to study nuclear structure from the National Institutes of Health (NIH) Common Fund as part of the...
As a postdoc studying chromosomal structure with David Agard and John Sedat in the late 1980s, Andrew Belmont had observed intriguing ultrastructural details in interphase nuclei. “We’d see large-scale fibers about 100 nanometers thick, and then there’d be a 10- to 30-nanometer-thick fiber looping...
