Research Publications

By giving artificial intelligence simple associative learning rules based on the brain circuits that allow a sea slug to forage — and augmenting it with better episodic memory, like that of an octopus — scientists have built an AI that can navigate new environments, seek rewards, map landmarks and...

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides...

Researchers from the University of Illinois have demonstrated the importance of cell-type-specific targeting in the treatment of HIV. Their findings, published in PNAS, are one of the first to examine the differential or cell-type...

A trio of researchers from the Department of Microbiology has discovered an essential function of a landmark protein in regulating movement across bacterial cells. Members of the Mera Lab determined how the coiled-coil polar protein TipN moves a region of the chromosome called parS. They also...

Some animals possess the remarkable ability to regenerate lost structures, exemplified by a lizard regrowing its tail. However, this regenerative process must be tightly regulated by the body to ensure proper tissue organization and to prevent abnormal growths, such as cancer. Yet, the precise...

Fragile X syndrome is one of the most commonly inherited forms of autism and intellectual disability, and no treatment currently exists. But a team of University of Illinois researchers led by Vipendra Kumar, a postdoctoral researcher in the Department of Molecular & Integrative Physiology, has...

The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent study. The findings, published in the journal...

A new study by University of Illinois scientist Dr. Kannanganattu V. Prasanth and his team of researchers at Illinois and across multiple institutions has shed light on a novel family of noncoding RNAs (ncRNAs), and their significant...

Chemists have determined for the first time the crystal structure and unlocked the mechanism of reaction activity of a key component of the monensin enzyme.  “The main finding was the first crystal structure for this family of enzymes,” said...