Cell & Developmental Biology

ORCA protein impacts timely cell replication in polycomb bodies present in cancer

In a new publication, University of Illinois School of Molecular & Cellular Biology researchers provide the first-ever comprehensive map of genomic regions near polycomb bodies in bone cancer cells. And, while mapping the genome around the polycomb repressive complex, the team led by professor...

Dr. Surabhi Sonam, CDB career seminar series founder, returns as speaker

Before Dr. Surabhi Sonam could be called “doctor,” wife, mother, or research specialist at the Roy J. Carver Biotechnology Center, she was a member of the CDB Graduate Student Association.In 2017, she and other members of the association had the idea of inviting alumni back to speak so current MCB...

MCB researchers uncover a novel mechanism of STAT3 activation in cancer

One day, on assignment researching non-canonical functions of aminoacyl-tRNA synthetases — housekeeping enzymes essential for protein synthesis — Pallob Barai noticed an intriguing pattern.“A particular AARS enzyme, TARS1, was found to be correlated with poor patient survival in different cancers,...

MCB scientists’ discovery begets new insights into cancer tumor growth

New research from the K.V. Prasanth lab, in collaboration with scientists across the University of Illinois and other institutions, has revealed that gene positioning near nuclear speckles — key nuclear domains that promote gene expression — along with the mechanistic functions of the non-coding...

MCB undergrads flourish in federal work-study CREW program

Ask any scientist and they’ll tell you what a joy it is to discover something they didn’t know they didn’t know. “The best parts of science tend to be serendipitous,” said the School of Molecular & Cellular Biology’s Jhewelle Fitz-Henley. “The things that you find out, you’re like, ‘I did not...

Highly cited researchers: Boxuan Zhao recognized for global impact

Though he only completed his postdoctoral work two years ago, the School of Molecular & Cellular Biology’s own Professor Boxuan Zhao already ranks among the world's most influential scientists. Earlier this month, Zhao was...

RNA binding protein implicated in brain development, fear memory

Researchers from the University of Illinois have identified an RNA binding protein called MOV10 as a critical factor in memory formation and learning. Their findings, published this month in BMC Biology, will...

Asking “Big questions”: UI researchers illuminate on transcriptional interplay among RNA polymerase enzymes

Investigators from the University of Illinois have created a whole-genome map that charts the occupancies of RNA polymerase enzymes in humans, discovering unexpected patterns in the process. Their findings appear in ...

The mystery of schistosomes: Q&A with parasitologist Jim Collins

Jim Collins’ research isn’t for the faint of heart — or stomach. “We don’t talk about it at the dinner table,” he laughed. Collins, a parasitologist who conducted his postdoctoral work at the University of Illinois, studies parasitic flatworms known as schistosomes. These parasites have caused...

With, not on: Reimagining autism in research

In the past six months, Laura Hetrick has spoken to more researchers than she has in her last 14 years at the University of Illinois Urbana-Champaign. “The last thing an autistic person wants to hear is, ‘You...