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Scientists link neuronal hyperactivity and broader tuning with altered sound processing
In a study that combines behavioral tests, computer models and electrophysiological recordings of neuron activity, researchers have found that hyperactivity of neurons in the auditory cortex and the reaction of these neurons to an unusually broad range of frequencies contribute to distorted...
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Illinois-led initiative will build precision phage platform for promoting health
University of Illinois Urbana-Champaign scientists, including microbiology professor Asma Hatoum-Aslan, will partner with investigators from several industrial and academic institutions on a five-year, up to $28M...
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Long-term alcohol use suspends liver cells in limbo, preventing regeneration
Excessive alcohol consumption can disrupt the liver’s unique regenerative abilities by trapping cells in limbo between their functional and regenerative states, even after a patient stops drinking, researchers at University of Illinois Urbana-Champaign and collaborators at Duke University and the...
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Microbiologists uncover novel proteins essential for maintaining magnesium homeostasis in Salmonella
In a newly published research, scientists from the School of Molecular & Cellular Biology have reported the discovery of novel proteins that keep Salmonella’s magnesium levels in balance.Yumi Iwadate, postdoctoral research...
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High-volume antibody testing platform could accelerate disease research and treatment development
Antibodies are the critical targeting agents of the immune system and the crux of immune therapy and vaccine development, but studying them is slow, expensive and labor-intensive. Now, researchers at the University of Illinois Urbana-Champaign have developed a new high-volume method that can...
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Map-making neurons change even in familiar settings, study finds
Neurobiologists at Northwestern University and the University of Illinois Urbana-Champaign, including Jason Climer in the School of Molecular & Cellular Biology, found the brain’s internal GPS changes each time mice navigate a...
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To overcome antibiotic resistance, new research says to let it flow
Some notoriously difficult to treat infections may not be as resistant to antibiotics as has been thought, according to new research using a microfluidic device that more closely duplicates the fluid flow found in the body than standard cultures.
The University of Illinois Urbana-Champaign...
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New study sheds light on liver maturation, specialization
Researchers from the University of Illinois have identified a key process coordinating liver maturation and polyploidization, a state in which cells carry more than two sets of chromosomes. Their findings, published in Genes and Development,...
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Mouse model reveals liver involvement in muscular dystrophy
A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1 — the most prevalent form of adult-onset muscular dystrophy — provides insight into why patients develop fatty liver disease and display hypersensitivity to medications, making treatment difficult. The new model opens...