Neuroscience

Christian Lab: Effects of epilepsy on neural activity in mice fluctuate with reproductive cycle, study finds

2018-10-14

Mice with epilepsy have altered patterns of neuron activity in the portion of the brain that controls the reproductive endocrine system, University of Illinois researchers report in a new study.

Study: Abnormal expression and phosphoinositide regulation of KCNQ/Kv7 channels linked to severe form of genetic epilepsy

2018-08-24

Molecular and integrative physiology professor Hee Jung Chung, postdoctoral fellow Eung Chang Kim, and their colleagues discovered that abnormal expression and phosphoinositide regulation of KCNQ/Kv7 potassium channels underlie neuronal hyperexcitability and injury in early-onset epileptic...

RNA-Binding protein, Mov10, is key to both survival and brain function

2018-07-24

A study led by Dr. Geena Skariah, a recent Neuroscience graduate of the Ceman lab in Cell and Developmental Biology, and current postdoctoral researcher at the University of Michigan, revealed the importance of the protein Mov10 (Moloney leukemia virus 10) in neurological development in animals....

Study: Protein found to be key component in irregularly excited brain cells

2018-07-17

Research scientist Kwan Young Lee, molecular and integrative physiology professor Nien-Pei Tsai, and their colleagues discovered that an overabundance of the tumor suppressor protein p53 in neurons can lead to impaired regulation of neuronal excitability in a mouse model of Fragile X syndrome.

Virtual predator is self-aware, behaves like living counterpart

2018-03-02

Rhanor Gillette and his colleagues built a virtual ocean predator that has simple self-awareness.

Chung Lab: Prolonged seizure activity causes caspase dependent cleavage and dysfunction of G-protein activated inwardly rectifying potassium channels.

2018-02-03

New findings suggest that novel down-regulation of GIRK channels by caspase-3 may contribute to NMDAR-dependent hippocampal atrophy following chronic epileptic seizures

NSF awards Illinois $3 million for interdisciplinary graduate student training

2017-07-31

Professor Martha Gillette will lead the program to form new insight on the brain and expand participation in field of brain science.

Assistant Professor Nien-Pei Tsai’s lab has published a study in PLOS Genetics on how a novel epilepsy-associated gene controls neuronal excitability

2017-02-28

Epilepsy is a medical condition characterized by spontaneous seizures due to hyperexcitability of brain neurons. Assistant Professor Nien-Pei Tsai, graduate student Jiuhe Zhu and colleagues uncovered that an insufficient function or mutations of a novel epilepsy-associated gene Nedd4-2 leads to...

Technological Breakthroughs Transform Biological Inquiry in Neuroscience

2016-12-31

The infinitely complex workings of the human brain have intrigued researchers for centuries. Our understanding of its workings have been limited, not by our curiosity, but by our tools. Now, with the growth of new molecular biology and genomics approaches, big data, and engineering advances that...

MCB Faculty Named Directors of LAS Graduate Programs

2016-09-27

Professor Satish Nair of the Department of Biochemistry has been appointed Director of the Center for Biophysics and Quantitative Biology. Professor Nair has been serving as Interim Director since November 2015. Professor Martha Gillette of the Department of Cell and Developmental Biology has been...

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