Mice with epilepsy have altered patterns of neuron activity in the portion of the brain that controls the reproductive endocrine system, University of Illinois researchers report in a new study.
Molecular and integrative physiology professor Hee Jung Chung, postdoctoral fellow Eung Chang Kim, and their colleagues discovered that abnormal expression and phosphoinositide regulation of KCNQ/Kv7 potassium channels underlie neuronal hyperexcitability and injury in early-onset epileptic...
A study led by Dr. Geena Skariah, a recent Neuroscience graduate of the Ceman lab in Cell and Developmental Biology, and current postdoctoral researcher at the University of Michigan, revealed the importance of the protein Mov10 (Moloney leukemia virus 10) in neurological development in animals....
Research scientist Kwan Young Lee, molecular and integrative physiology professor Nien-Pei Tsai, and their colleagues discovered that an overabundance of the tumor suppressor protein p53 in neurons can lead to impaired regulation of neuronal excitability in a mouse model of Fragile X syndrome.
New findings suggest that novel down-regulation of GIRK channels by caspase-3 may contribute to NMDAR-dependent hippocampal atrophy following chronic epileptic seizures
Epilepsy is a medical condition characterized by spontaneous seizures due to hyperexcitability of brain neurons. Assistant Professor Nien-Pei Tsai, graduate student Jiuhe Zhu and colleagues uncovered that an insufficient function or mutations of a novel epilepsy-associated gene Nedd4-2 leads to...
The infinitely complex workings of the human brain have intrigued researchers for centuries. Our understanding of its workings have been limited, not by our curiosity, but by our tools. Now, with the growth of new molecular biology and genomics approaches, big data, and engineering advances that...
Professor Satish Nair of the Department of Biochemistry has been appointed Director of the Center for Biophysics and Quantitative Biology. Professor Nair has been serving as Interim Director since November 2015. Professor Martha Gillette of the Department of Cell and Developmental Biology has been...
