Neuroscience

Epilepsy is a medical condition characterized by spontaneous seizures due to hyperexcitability of brain neurons. Assistant Professor Nien-Pei Tsai, graduate student Jiuhe Zhu and colleagues uncovered that an insufficient function or mutations of a novel epilepsy-associated gene Nedd4-2 leads to...

The infinitely complex workings of the human brain have intrigued researchers for centuries. Our understanding of its workings have been limited, not by our curiosity, but by our tools. Now, with the growth of new molecular biology and genomics approaches, big data, and engineering advances that...

Professor Satish Nair of the Department of Biochemistry has been appointed Director of the Center for Biophysics and Quantitative Biology. Professor Nair has been serving as Interim Director since November 2015. Professor Martha Gillette of the Department of Cell and Developmental Biology has been...

Gillette, professor of cell and developmental biology, and colleagues will collaborate on various projects involving innovative single cell analysis in brain and the creation of biological machines in hopes of creating new diagnostic and therapeutic tools.

The Ceman laboratory, with lead authors Phil Kenny and Miri Kim, have shown that FMRP is able to facilitate or suppress the translation of a subset of its target mRNAs by its interaction with the RNA helicase MOV10.

A Team led by Martha Gillette, professor of Cell and Developmental Biology, Molecular and Integrative Physiology, Neuroscience and Bioengineering, has been awarded a BRAIN EAGER grant from NSF for a project titled “Multiscale dynamics and emergent properties of suprachiasmatic circuits in real time...

William T. Greenough, a professor emeritus of psychology, was a pioneer in studies of brain development, the neural basis of learning and memory, and the effects of aging, exercise, injury and environmental enrichment on the brain.

Although cellular metabolic (redox) state has long been associated with a housekeeping role, recent research from a team lead by Martha Gillette, and including the Lee Cox and Jonathan Sweedler groups, provides new insights on cellular redox states, linking them to the intrinsic daily (circadian)...

Professor of Molecular and Integrative Physiology and Neuroscience Rhanor Gillette and colleagues have published a paper in the Journal of Neurophysiology: "Nitric oxide potentiates cAMP-gated cation current by intracellular acidification in feeding neurons of Pleurobranchaea."

In this article, Associate Professor of Cell and Developmental Biology Stephanie Ceman discusses her research on Fragile X Syndrome.