Cancer Center

The Cancer Center at Illinois brings together cancer biologists, clinicians, engineers, and other specialists to accelerate advances in disease detection, prevention, therapy, and improve quality of life for patients.

Cholesterol metabolite causes immune system to attack T cells instead of breast cancer, study finds

2020-09-15

In breast cancer tumors, a molecule produced when the body breaks down cholesterol hijacks the myeloid immune cells that normally arm T cells to fight cancer, a new study in mice found. Instead, the hijacked myeloid cells disarm the T cells and even tell them to self-destruct.

Engineered immune cells recognize, attack human and mouse solid-tumor cancer cells

2020-06-29

Silhouette of Preeti Sharma holding up a 250 ml pyrex vial with a bit of liquid inside against a window.

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia. It modifies a patient’s own T-cells by adding a piece of an antibody that recognizes unique features on the surface of cancer cells. In a new study, researchers report that they...

Cholesterol metabolite causes immune system to attack T cells instead of breast cancer, study finds

Engineered immune cells recognize, attack human and mouse solid-tumor cancer cells

MIP Professor Benita Katzenellenbogen named Senior Advisor for the Cancer Center at Illinois

Researchers in MIP Explore Link Between Ovarian Cancer and Cholesterol

Hitting the (Moving) Target of Drug Resistant Cancers

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