MCB researchers uncover a novel mechanism of STAT3 activation in cancer

Pallob Barai and Reean Abdullah at the lab bench
One day, on assignment researching non-canonical functions of aminoacyl-tRNA synthetases — housekeeping enzymes essential for protein synthesis — Pallob Barai noticed an intriguing pattern.“A particular AARS enzyme, TARS1, was found to be correlated with poor patient survival in different cancers,...

Uncovering the Critical Function of Drg1 in Protein Synthesis

Headshot of Hong Jin
Biochemistry researchers at the University of Illinois Urbana-Champaign are conducting trailblazing work on a group of conserved proteins that are directly related to abnormal cell proliferation and developmental and neurological disorders. In a new article published in Cell Reports, biochemistry...

Researchers find protein that suppresses muscle repair in mice

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Researchers report that a protein known to be important to protein synthesis also influences muscle regeneration and regrowth in an unexpected manner. The discovery, reported in the Journal of Clinical Investigation, could one day lead to new methods for treating disorders that result in muscle...