Cell

Cell Press publishes more than 50 scientific journals both independently and in partnership with scientific societies. Subjects range across life, physical, earth, and health sciences.

Piecing together the LanCL puzzle

2021-05-03

Removing the phosphate group from kinases can activate them, which can be problematic. LanCL adds glutathione to these kinases, after which they became deactivated.

Researchers from the Carl R. Woese Institute for Genomic Biology, including several faculty in the School of Molecular & Cellular Biology, in collaboration with scientists at Oxford University have published a paper in Cell reporting the function of LanCL proteins. These proteins...

Structural and computational analyses provide the first view of an activated AMPA receptor. Findings published by the Tajkhorshid and Gouaux labs in Cell.

2018-01-26

Using molecular dynamics simulations, the Tajkhorshid lab computationally modeled the complete structure of the active AMPA receptor with hydrated ions moving through an open pore. Together these findings, published in Cell, show how AMPA receptor regulatory proteins enhance the potency of agonists...

Piecing together the LanCL puzzle

Structural and computational analyses provide the first view of an activated AMPA receptor. Findings published by the Tajkhorshid and Gouaux labs in Cell.

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