Education
Chemistry, Ph.D., University of Pennsylvania
Bioengineering, M.S.E., University of Pennsylvania
Chemistry, B.A., Cornell University
Additional Campus Affiliations
Professor, Biochemistry
Affiliate, Carl R. Woese Institute for Genomic Biology
Recent Publications
Bagde, S. R., & Kim, C.-Y. (2024). Architecture of full-length type I modular polyketide synthases revealed by X-ray crystallography, cryo-electron microscopy, and AlphaFold2. Natural Product Reports, 41(8), 1219-1234. https://doi.org/10.1039/D3NP00060E
Gade, P., Erlandson, A., Ullah, A., Chen, X., Mathews, I. I., Mera, P. E., & Kim, C. Y. (2023). Structural and functional analyses of the echinomycin resistance conferring protein Ecm16 from Streptomyces lasalocidi. Scientific reports, 13(1), Article 7980. https://doi.org/10.1038/s41598-023-34437-9
Wang, Q., Liu, N., Deng, Y., Guan, Y., Xiao, H., Nitka, T. A., Yang, H., Yadav, A., Vukovic, L., Mathews, I. I., Chen, X., & Kim, C. Y. (2023). Triepoxide formation by a flavin-dependent monooxygenase in monensin biosynthesis. Nature communications, 14(1), Article 6273. https://doi.org/10.1038/s41467-023-41889-0
Erlandson, A., Gade, P., Menikpurage, I. P., Kim, C. Y., & Mera, P. E. (2022). The UvrA-like protein Ecm16 requires ATPase activity to render resistance against echinomycin. Molecular Microbiology, 117(6), 1434-1446. https://doi.org/10.1111/mmi.14918
Bagde, S. R., Mathews, I. I., Fromme, J. C., & Kim, C. Y. (2021). Modular polyketide synthase contains two reaction chambers that operate asynchronously. Science, 374(6568), Article A40. https://doi.org/10.1126/science.abi8532
