In a new paper published in mBio, researchers in the Department of Microbiology show that polyamines are critical for adaptation of salmonella to low magnesium conditions, including those found in the macrophage phagosome.
Salmonella are major food-borne pathogens...
Dr. Yumi Iwadate is a postdoctoral fellow in the Slauch Lab in the Department of Microbiology and serves as one of two postdoctoral advisors for the Microbial Early-Career Researchers Association (MicroERA). She is featured in this month’s Microbial Systems Initiative researcher spotlight as a lead...
The regulation of polyamines is essential for the physiological function of organisms. Simplistically, polyamines are organic cations that interact with RNA, including ribosomes and translational machinery. Both the lack of and an excess of polyamines confer lethal phenotypes, though the molecular...