Anakk Lab: The consequences of losing a scaffold

The Anakk lab has investigated the metabolic repercussions of deleting the scaffolding protein IQGAP1. These findings were published in a paper entitled "Identification of IQ motif-containing GTPase Activating Protein 1 as a regulator of long-term ketosis" in JCI Insight.

Study: Damaged liver cells undergo reprogramming to regenerate

New research conducted by biochemists at the University of Illinois has determined how damaged liver cells repair and restore themselves through a signal to return to an early stage of postnatal organ development. The findings are reported in the journal Nature Structural & Molecular Biology.

Study: Kidney stones have distinct geological histories

Using a suite of techniques both common and new to geology and biology, researchers, from left, M.D./Ph.D. student Jessica Saw, geologist and microbiologist Bruce Fouke, microscopy expert and plant biologist Mayandi Sivaguru and their colleagues made new discoveries about how kidney stones...

Tajkhorshid Lab: Battling antimicrobial resistance

Each year, at least 23,000 people die from infections caused by antibiotic resistant bacteria in the U.S., according to the Centers for Disease Control and Prevention. Using computer modeling, researchers from the University of Illinois at Urbana-Champaign and Sandia National Laboratories are...

K.V. Prasanth lab discovers cancer connections with MALAT1

Prasanth’s lab published several papers on a particular lncRNA called MALAT1, with significant findings showing an important link between cancer and MALAT1. They found that when MALAT1 is overexpressed in breast cells, the cells form tumors. Conversely, when it is depleted in breast cancer cells,...