Researchers structurally characterize a dual-function transporter

The regulation of glutamate, an excitatory neurotransmitter abundant in the central nervous system, is critical for maintaining normal brain function. Glutamate regulation is achieved via extracellular transport of the amino acid. There are two primary classes of proteins involved in the transport...

MCB statement on solidarity with Asian American communities

The MCB community stands together in denouncing all acts of hate against Asians and Asian Americans, just as we denounce all acts of intolerance and hate within and outside our MCB community. We stand in solidarity with our Asian and Asian American colleagues against the forces of intolerance and...

Division of labor within regenerating liver maintains metabolism, mouse study finds

The liver has a rare superpower among body organs – the ability to regenerate, even if 70% of its mass is removed. It also keeps up its metabolic and toxin-removing work during the process of regeneration, thanks to a subset of cells that expand their workload while the rest focus on multiplication...

Researchers examine the biological role of epigenetic regulator Brd4 in inflammasome activation

Inflammasomes play a critical role in the innate cellular immune response to pathogen infection. The inflammasome, a cytosolic multiprotein complex, recognizes substrates produced during infection or tissue damage, and triggers an inflammatory response by releasing the proinflammatory cytokine IL-...

Cronan lab uncovers mechanism for synthesis of pimelate moiety, the biotin precursor

Professor John. E. Cronan, Microbiology Alumni Professor and professor of biochemistry at the University of Illinois, is a leading researcher and innovator in the field of lipid metabolism. His recent work focuses on the synthesis of biotin and its building blocks across different species of...

Wu and collaborators develop new molecules which attack the virus that causes COVID-19 and resist 'escape' mutations

An international team of researchers including Nicholas Wu, a professor in the Department of Biochemistry, has published a new study which developed highly potent molecules that can neutralize SARS-CoV-2 by simultaneously targeting multiple sites of vulnerability on the virus.

New study: MCB faculty among world's most influential researchers

Several faculty from the School of Molecular & Cellular Biology were among the most-cited researchers in the world in a new, widely hailed analysis designed to provide a clearer view of scientific and scholarly impact.

Unraveling mechanisms of FXR in protection against liver diseases

Obesity is rising in prevalence and poses a major concern for the health of our general population. Currently affecting over one-third of the population of the United States, obesity is often comorbid with other diseases, such as diabetes, fatty liver disease, cardiovascular disease, and some...

Welcome to Professor Nicholas Wu

Professor Wu was one of ten new faculty hires made in the School of Molecular and Cellular Biology in the last three years. Wu is an assistant professor of and is an affiliate of the Carl R. Woese Institute for Genomic Biology.

Welcome to Professor Beth Stadtmueller

Professor Stadtmueller was one of ten new faculty hires made in the School of Molecular and Cellular Biology in the last three years. Stadtmueller is an assistant professor of biochemistry, assistant professor of Biomedical and Translational Sciences with the Carle Illinois College of Medicine, and...