Biochemistry

CAR-T immune therapy attacks ovarian cancer in mice with a single dose

CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor...

Team identifies key driver of cancer cell death pathway that activates immune cells

Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.

In Memoriam: Biochemistry professor Ed Conrad

With great sadness, the Department of Biochemistry and School of Molecular & Cellular Biology announce the passing of professor Emeritus H. Edward Conrad, 94, on May 23, 2023, in Urbana.

Beckman Institute announces 2023 fellowship, award recipients

Twelve students have been selected to receive 2023 Beckman Institute fellowships and awards. The awards, which fund interdisciplinary research that takes place over the summer, will be celebrated at a poster session on July 28, 2023.

Members of MCB labs earn newly-established fellowships focused on cancer research

The Beckman Institute has announced its 2023 class of six postdoctoral fellows. Fellows are selected in accordance with the core values of the institute: excellence, collaboration, integrity, transdisciplinarity, exploration, and diversity.

Illinois to co-lead new CZ Biohub in Chicago

The University of Illinois Urbana-Champaign has been chosen to lead the Chan Zuckerberg Biohub Chicago – a new biomedical hub – along with the University of Chicago and Northwestern University. The three-university team was selected to lead the new biomedical hub as part of a competitive...

Wind-chill out! Researchers discover how flow stresses out bacterial pathogens

Researchers have discovered the addition of fluid to human pathogens triggers a "windchill-like" effect that sensitizes cells to hydrogen peroxide, a well-known agent of cell stress and DNA damage. Their findings have been published in PNAS.

Possible genetic basis and mouse model found for severe nonalcoholic fatty liver disease

The SRSF1 gene acts as a guardian against DNA damage in the liver, School of MCB researchers found. When it is missing or inactivated, severe nonalcoholic fatty liver disease symptoms develop.

Biochemistry professor partners with researchers across campus for genomics workshop

The Osher Lifelong Learning Institute (OLLI) has partnered with University of Illinois researchers, including biochemistry professor Hong Jin, to offer a new workshop called, “What’s in my blood? Genomics Testing and You.”

Researchers demonstrate new cancer drug development method

Researchers from the School of Molecular & Cellular Biology at the University of Illinois Urbana-Champaign and the University of Illinois Chicago collaborated to highlight lipid-protein interaction as a new avenue for oncology drug development.