Skip to main content

Institute for Genomic Biology (IGB)

The Carl R. Woese Institute for Genomic Biology (IGB) is dedicated to transformative research and technology in life sciences. Team-based themes tackle grand societal challenges in food security, energy, health, technology, and environmental conservation. Its facilities include a microfabrication lab, plant growth facility, and a microscopy suite.

Study investigates the effects of DiNP on the colon

Phthalates are commonly used to make products—including artificial leather, footwear, plastic food packaging, and personal care products—more flexible or stable. In particular, di-isononyl phthalate is incorporated in vinyl clothing and construction materials. However, scientists do not completely...

Decoding the molecular clock that controls neurogenesis in visual center of Drosophila

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern. In a new study, published in Nature Communications, researchers have uncovered the molecular players involved and how the timing is controlled.

MCB team identifies compound with potent antiseizure effects

Researchers studying epileptic seizures of the temporal lobe – the most common type of epilepsy – discovered a compound that reduces seizures in the hippocampus, a brain region where many such seizures originate. The compound, known as TC-2153, lessened the severity of seizures in mice. The...

'Molecular Velcro' enables tissues to sense, react to mechanical force

The Velcro-like cellular proteins that hold cells and tissues together also perform critical functions when they experience increased tension. A new University of Illinois Urbana-Champaign study observed that when tugged upon in a controlled manner, these proteins – called cadherins – communicate...

Quantum leaps in understanding how living corals survive

Coral reefs have thrived for millions of years in their shallow ocean water environments due to their unique partnerships with the algae that live in their tissues. Corals provide a safe haven and carbon dioxide while their algal symbionts provide them with food and oxygen produced from...

Gene mutation leads to epileptic encephalopathy symptoms, neuron death in mice

Mice with a genetic mutation that’s been observed in patients with epileptic encephalopathy, a severe form of congenital epilepsy, exhibit not only the seizure, developmental and behavioral symptoms of the disorder, but also neural degeneration and inflammation in the brain, University of Illinois...

University of Illinois iGEM Team 2021 Brings Home Bronze Medal

CABBI and the Carl R. Woese Institute for Genomic Biology (IGB) are sponsoring six undergraduate students from the University of Illinois Urbana-Champaign to take part in the International Genetically Engineered Machine (iGEM) Competition during Spring and Summer 2021. The annual iGEM Jamboree is...

Chemical pollutants disrupt reproduction in anemonefish, study finds

Ocean pollution is unfortunately becoming more commonplace, raising concerns over the effect of chemicals that are leaching into the water. In a new study, researchers have discovered how these chemicals can affect the reproduction in common anemonefish Amphiprion ocellaris.

Study reveals how bacterial pathogen adapts to nutritional stress

In order to cause disease, the human pathogen Staphylococcus aureus must adapt to the changing host environment. Many of these adaptations are mediated through two-component signal transduction systems (TCSs) that coordinate gene expression in response to environmental stimuli. In a new study...

Scientists discover how antibiotics penetrate Gram-negative bacterial cell walls

In a study reported in the journal Chemical Science, researchers developed a new method to determine how antibiotics with specific chemical properties thread their way through tiny pores in the otherwise impenetrable cell envelopes of Gram-negative bacteria.