Scientists engineer human T cell receptors against cancer antigens

Graduate student Sheena Smith and Professor David Kranz of the Department of Biochemistry have developed an approach to discover T cell receptors that could be therapeutically useful against different cancers. In collaboration with graduate students Yuhang Wang and Javier Baylor and Professor Emad...

Scientists discover a new role for estrogen in the pathology of breast cancer

Biochemistry professor David Shapiro, M.D.-Ph.D student Neal Andruska, graduate student Xiaobin Zheng and their colleagues discovered a new mechanism by which estrogen contributes to the pathology of breast cancer. The findings are published in the journal Oncogene.

Team finds mechanism linking key inflammatory marker to cancer

In a new study described in the journal Oncogene, Professor of Biochemistry Lin-Feng Chen and his team reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer

Assistant Professor of Biochemistry and Medical Biochemistry at the College of Medicine Lin-Feng Chen is corresponding author on a new study on RUNX3, a tumor suppressor in breast cancer.

Team discovers how a cancer-causing bacterium spurs cell death

A new study led by Professor of Microbiology Stephen Blanke, in Proceedings of the National Academy of Sciences, is the first to show how a bacterial toxin can disrupt a cell's mitochondria – its energy-generation and distribution system – to disable the cell and spur apoptosis (programmed cell...

Kannanganattu Prasanth Awarded ACS Research Scholar Grant

Assistant Professor of Cell and Developmental Biology Kannanganattu Prasanth has been awarded a Research Scholar Grant from the American Cancer Society.

$8 Million NIH Grant To Study Effects of Botanical Estrogens

Swanlund Professor of Molecular and Integrative Physiology and Cell and Developmental Biology Benita Katzenellenbogen is among three University of Illinois faculty funded by a new grant.

Cancer-causing bacterium targets tumor-suppressor protein

Assistant Professor of Biochemistry Lin-Feng Chen and colleagues have discovered a mechanism by which Helicobacter pylori, the only known cancer-causing bacterium, disables a tumor suppressor protein in host cells.

Benita Katzenellebogen Helps Discover How Estrogen Can Prevent Vascular Disease Without Increasing Cancer Risk

Swanlund Professor of Molecular and Integrative Physiology and Cell and Developmental Biology Benita Katzenellebogen contributed to a study led by University of Texas Southwestern Medical Center that pinpointed a set of biological mechanisms through which estrogen confers its beneficial effects on...

Ann Nardulli Meets with Lawmakers in Washington D.C.

Professor of Molecular and Integrative Physiology Ann Nardulli visited Capitol Hill, along with other members of the Endocrine Society, as part of an envoy to present the 2009 Endocrine Society Congressional Leadership Award, and to advocate for increased funding for biomedical research.