Professor Kannanganattu Prasanth led a team that found that certain genes that don’t code for proteins could play an important regulatory role in breast cancer.
The Prasanths began a new life as postdoctoral researchers at Cold Spring Harbor Laboratory in New York. And today, as University of Illinois CDB professors, they continue to work side by side — literally. Their respective labs are next to each other in the Chemical and Life Sciences Building...
Prasanth’s lab published several papers on a particular lncRNA called MALAT1, with significant findings showing an important link between cancer and MALAT1. They found that when MALAT1 is overexpressed in breast cells, the cells form tumors. Conversely, when it is depleted in breast cancer cells,...
The Kranz lab and colleagues have recently publish a trio of papers that describe the engineering of receptors that can mediate specific and potent destruction of cancers by T cells.
For decades, MCB and the University of Illinois have been at the forefront of understanding the role of estrogen and the estrogen receptor (ER) in causing breast cancer. This is essential work: Breast cancer is the most commonly diagnosed cancer in women, affecting roughly one in eight women in the...
Benita Katzenellenbogen has delved into the causes and treatments for breast cancer and other hormone-dependent cancers for virtually her entire career. Her tireless work in the field has established her as a world-renowned expert.
The study, reported in Nature Communications, identifies new potential drug targets that could inhibit the creation or actions of the dangerous cholesterol byproduct.
The Department of Biochemistry and the School of Molecular and Cellular Biology congratulate Professor David Shapiro, who has been named the Eugene Howe Scholar in Biochemistry.
Through the ages, fertility has played a central role in civilizations. Its cultural, socioeconomic, demographic, religious and global implications were and still are incalculable. A Wikipedia search for “fertility gods,” for example, yields a list of 35 cultures with one, and often...
