Cancer

For decades, MCB and the University of Illinois have been at the forefront of understanding the role of estrogen and the estrogen receptor (ER) in causing breast cancer. This is essential work: Breast cancer is the most commonly diagnosed cancer in women, affecting roughly one in eight women in the...

Benita Katzenellenbogen has delved into the causes and treatments for breast cancer and other hormone-dependent cancers for virtually her entire career. Her tireless work in the field has established her as a world-renowned expert.

The study, reported in Nature Communications, identifies new potential drug targets that could inhibit the creation or actions of the dangerous cholesterol byproduct.

The Department of Biochemistry and the School of Molecular and Cellular Biology congratulate Professor David Shapiro, who has been named the Eugene Howe Scholar in Biochemistry.

Through the ages, fertility has played a central role in civilizations. Its cultural, socioeconomic, demographic, religious and global implications were and still are incalculable. A Wikipedia search for “fertility gods,” for example, yields a list of 35 cultures with one, and often...

The Society’s highest honor, this annual award recognizes lifetime achievements and exceptional contributions to the field of endocrinology. Dr. Benita Katzenellenbogen is currently the Swanlund Chaired Professor of Molecular and Integrative Physiology, and Dr. John Katzenellenbogen is the Swanlund...

Biochemistry researchers in Dr. David Shapiro's lab, and a study team including researchers from the department of food science and human nutrition, the department of molecular and integrative physiology, the College of Medicine and the Cancer Center, have developed a new drug that kills estrogen...

An interdisciplinary research team, including molecular and integrative physiology professors Benita Katzenellenbogen and Milan Bagchi, has developed a new approach to treating endometriosis. Their research appears in Science Translational Medicine.

Graduate student Sheena Smith and Professor David Kranz of the Department of Biochemistry have developed an approach to discover T cell receptors that could be therapeutically useful against different cancers. In collaboration with graduate students Yuhang Wang and Javier Baylor and Professor Emad...

Biochemistry professor David Shapiro, M.D.-Ph.D student Neal Andruska, graduate student Xiaobin Zheng and their colleagues discovered a new mechanism by which estrogen contributes to the pathology of breast cancer. The findings are published in the journal Oncogene.