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Researchers demonstrate new cancer drug development method

Researchers from the School of Molecular & Cellular Biology at the University of Illinois Urbana-Champaign and the University of Illinois Chicago collaborated to highlight lipid-protein interaction as a new avenue for oncology drug development.

Experts boost activity of potential therapeutic target in triple-negative breast cancer

CHAMPAIGN, Ill. — Less than 20% of diagnosed breast cancers are designated “triple-negative,” meaning that the affected tissues lack three types of receptors often found in other breast cancer types, but TNBCs are often aggressive with ...

New faculty members begin teaching and research at U of I

The College of LAS is welcoming 38 new professors for the 2022-23 academic year. Their new positions range from clinical professors to assistant professors and an endowed position in more than 20 academic units, ranging from African American studies to economics, philosophy, statistics, and several...

Cancer Center at Illinois announces 2022 cancer research grant recipients

The Cancer Center at Illinois is proud to announce the selection of nine interdisciplinary cancer research projects, involving multiple MCB faculty members, designed by University of Illinois Urbana-Champaign faculty to be funded by Cancer Center at Illinois (CCIL) developmental grant awards.

New therapeutic target identified for triple-negative breast cancer

Breast cancer is categorized into three major subtypes: hormone receptor-positive, HER2-positive, and triple-negative. Although there are targeted therapeutic approaches for the first two, there are limited options for triple negative-breast cancer patients. In a new study, researchers have...

Light-activated technique helps bring cell powerhouses back into balance

University of Illinois biochemistry professor Kai Zhang and collaborators developed a technique using light to regulate mitochondria, the energy-producing powerhouses inside cells. The technique could address mitochondrial diseases and cancer.

Prasanth lab uncovers new insights into the role of Orc6 in the maintenance of genome integrity

New research from Supriya Prasanth’s lab at the University of Illinois provides tremendous insight into the role of the smallest subunit of the human ORC, Orc6. Although the ORC is conserved in all eukaryotes, Orc6 is the most evolutionarily diverged. In a recent study published in PNAS, the...

Exploring RNA’s Binding Role in Liver Disease and Cancer

Kalsotra’s research has focused on RNA, the workhorse cousin of DNA, which makes up the genetic instructions for living things. RNA is often viewed as important for messaging and other functions, taking DNA’s code and transporting it to and carrying out functions in cells. It’s often taken a back...

Taking a Deep Look at Protein Structures that Contribute to Cancer

Thirteen years ago, when Lin-Feng Chen joined the Department of Biochemistry, he had his sights set on a specific protein that could both contribute to the growth of cancer and be a major factor in boosting the body’s immune system.

Harnessing and Boosting T-cells to Fight Disease

David Kranz, the Phillip A. Sharp Professor of Biochemistry in the School of Molecular and Cellular Biology, has been involved in T-cell research since working as a postdoctoral researcher at the Massachusetts Institute of Technology, involved in early discoveries about how T-cells might be used to...