Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75 percent of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these...

CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor...

Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.

Through a new approach of cross-linking cell proteins directly to a protein of interest, researchers at the University of Illinois Urbana-Champaign’s School of Molecular & Cellular Biology have distinguished new patterns of cell interactions with a molecular chaperone.  

Researchers from the School of Molecular & Cellular Biology at the University of Illinois Urbana-Champaign and the University of Illinois Chicago collaborated to highlight lipid-protein interaction as a new avenue for oncology drug development.

CHAMPAIGN, Ill. — Less than 20% of diagnosed breast cancers are designated “triple-negative,” meaning that the affected tissues lack three types of receptors often found in other breast cancer types, but TNBCs are often aggressive with ...

The College of LAS is welcoming 38 new professors for the 2022-23 academic year. Their new positions range from clinical professors to assistant professors and an endowed position in more than 20 academic units, ranging from African American studies to economics, philosophy, statistics, and several...

The Cancer Center at Illinois is proud to announce the selection of nine interdisciplinary cancer research projects, involving multiple MCB faculty members, designed by University of Illinois Urbana-Champaign faculty to be funded by Cancer Center at Illinois (CCIL) developmental grant awards.

Breast cancer is categorized into three major subtypes: hormone receptor-positive, HER2-positive, and triple-negative. Although there are targeted therapeutic approaches for the first two, there are limited options for triple negative-breast cancer patients. In a new study, researchers have...

University of Illinois biochemistry professor Kai Zhang and collaborators developed a technique using light to regulate mitochondria, the energy-producing powerhouses inside cells. The technique could address mitochondrial diseases and cancer.