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Colorectal cancer treated with cholesterol inhibitor in U. of I. study
University of Illinois researchers have successfully treated a common type of colorectal cancer tumor with a cholesterol inhibitor drug, demonstrating a promising treatment for the disease in animal experiments.The study,...
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New study reveals critical regulatory role of protein BRD4 in colorectal cancer chemotherapy resistance
School of Molecular & Cellular Biology professor Lin-Feng Chen has published new research reporting an important factor driving chemoresistance for patients with colorectal cancer. The research was published in the journal...
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Congratulations to 2024 College of LAS Alumni Award Honoree Dr. Michelle Barton
Dr. Michelle (Shelley) Barton’s remarkable career in cancer research, leadership, and graduate education is a testament to resilience, innovation, and an unwavering commitment to scientific advancement. As a researcher, she played a pivotal role in the discovery of TRIM24, a protein found in...
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Meet Diana Ranoa, new assistant professor of biochemistry
The School of Molecular & Cellular Biology and Department of Biochemistry are pleased to welcome Dr. Diana Ranoa as assistant professor of biochemistry. Dr. Ranoa...
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New campuswide project will develop rapid manufacturing of tumor models
Researchers at the University of Illinois Urbana-Champaign will develop a radically new platform to manufacture tumor models and expand their availability for medical research and personalized medicine, thanks to a $21 million grant from the Advanced Research Projects...
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Overcoming drug resistance in breast cancer treatment
An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer.
Their findings, published in Breast Cancer Research and Treatment,...
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Unprecedented Compound Takes a Step Toward Breast Cancer Clinical Trials
Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75 percent of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these...
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CAR-T immune therapy attacks ovarian cancer in mice with a single dose
CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor...
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Team identifies key driver of cancer cell death pathway that activates immune cells
Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.
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Researchers identify new patterns of cell interactions with molecular chaperone
Through a new approach of cross-linking cell proteins directly to a protein of interest, researchers at the University of Illinois Urbana-Champaign’s School of Molecular & Cellular Biology have distinguished new patterns of cell interactions with a molecular chaperone.