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Cancer

New campuswide project will develop rapid manufacturing of tumor models

Researchers at the University of Illinois Urbana-Champaign will develop a radically new platform to manufacture tumor models and expand their availability for medical research and personalized medicine, thanks to a $21 million grant from the Advanced Research Projects...

Overcoming drug resistance in breast cancer treatment

An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer. Their findings, published in Breast Cancer Research and Treatment,...

Unprecedented Compound Takes a Step Toward Breast Cancer Clinical Trials

Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75 percent of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these...

CAR-T immune therapy attacks ovarian cancer in mice with a single dose

CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor...

Team identifies key driver of cancer cell death pathway that activates immune cells

Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.

Researchers identify new patterns of cell interactions with molecular chaperone

Through a new approach of cross-linking cell proteins directly to a protein of interest, researchers at the University of Illinois Urbana-Champaign’s School of Molecular & Cellular Biology have distinguished new patterns of cell interactions with a molecular chaperone.  

Researchers demonstrate new cancer drug development method

Researchers from the School of Molecular & Cellular Biology at the University of Illinois Urbana-Champaign and the University of Illinois Chicago collaborated to highlight lipid-protein interaction as a new avenue for oncology drug development.

Experts boost activity of potential therapeutic target in triple-negative breast cancer

CHAMPAIGN, Ill. — Less than 20% of diagnosed breast cancers are designated “triple-negative,” meaning that the affected tissues lack three types of receptors often found in other breast cancer types, but TNBCs are often aggressive with ...

New faculty members begin teaching and research at U of I

The College of LAS is welcoming 38 new professors for the 2022-23 academic year. Their new positions range from clinical professors to assistant professors and an endowed position in more than 20 academic units, ranging from African American studies to economics, philosophy, statistics, and several...

Cancer Center at Illinois announces 2022 cancer research grant recipients

The Cancer Center at Illinois is proud to announce the selection of nine interdisciplinary cancer research projects, involving multiple MCB faculty members, designed by University of Illinois Urbana-Champaign faculty to be funded by Cancer Center at Illinois (CCIL) developmental grant awards.