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In new research, Van Bortle Lab untangles a noncoding RNA-based mechanism of cancer progression
Researchers from the University of Illinois Urbana-Champaign are piecing together how cancer-emergent non-coding RNAs, or ncRNAs, contribute to disease-related cell phenotypes. The Van Bortle lab has focused extensively on RNA polymerase III (Pol III) —...
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Researchers aim to disrupt breast cancer line of communication and prevent spread
University of Illinois researcher Erik Nelson and members of his lab have made an important discovery about the relationship between cholesterol and breast cancer progression with crucial implications for breast cancer therapeutics....
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A cellular protein, FGD3, boosts breast cancer chemotherapy, immunotherapy
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report. The protein, FGD3,...
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Colorectal cancer treated with cholesterol inhibitor in U. of I. study
University of Illinois researchers have successfully treated a common type of colorectal cancer tumor with a cholesterol inhibitor drug, demonstrating a promising treatment for the disease in animal experiments.The study,...
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New study reveals critical regulatory role of protein BRD4 in colorectal cancer chemotherapy resistance
School of Molecular & Cellular Biology professor Lin-Feng Chen has published new research reporting an important factor driving chemoresistance for patients with colorectal cancer. The research was published in the journal...
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Congratulations to 2024 College of LAS Alumni Award Honoree Dr. Michelle Barton
Dr. Michelle (Shelley) Barton’s remarkable career in cancer research, leadership, and graduate education is a testament to resilience, innovation, and an unwavering commitment to scientific advancement. As a researcher, she played a pivotal role in the discovery of TRIM24, a protein found in...
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Meet Diana Ranoa, new assistant professor of biochemistry
The School of Molecular & Cellular Biology and Department of Biochemistry are pleased to welcome Dr. Diana Ranoa as assistant professor of biochemistry. Dr. Ranoa...
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New campuswide project will develop rapid manufacturing of tumor models
Researchers at the University of Illinois Urbana-Champaign will develop a radically new platform to manufacture tumor models and expand their availability for medical research and personalized medicine, thanks to a $21 million grant from the Advanced Research Projects...
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Overcoming drug resistance in breast cancer treatment
An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer.
Their findings, published in Breast Cancer Research and Treatment,...
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Unprecedented Compound Takes a Step Toward Breast Cancer Clinical Trials
Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75 percent of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these...