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Genomics

Prasanth lab uncovers new insights into the role of Orc6 in the maintenance of genome integrity

New research from Supriya Prasanth’s lab at the University of Illinois provides tremendous insight into the role of the smallest subunit of the human ORC, Orc6. Although the ORC is conserved in all eukaryotes, Orc6 is the most evolutionarily diverged. In a recent study published in PNAS, the...

Decoding the molecular clock that controls neurogenesis in visual center of Drosophila

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern. In a new study, published in Nature Communications, researchers have uncovered the molecular players involved and how the timing is controlled.

Meet MCB: Professor Brian Freeman brings molecular chaperone expertise to Illinois

Brian Freeman, a professor of cell and developmental biology and Cancer Center at Illinois scientist, has focused his research on the study of molecular chaperones (MCs) since the beginning of his career as a graduate student when chaperones were thought to have no medicinal purpose. Now, the...

New analytical technique helps researchers spot subtle differences in subcellular chemistry

Researchers at the University of Illinois Urbana-Champaign can now rapidly isolate and chemically characterize individual organelles within cells. The new technique tests the limits of analytical chemistry and rapidly reveals the chemical composition of organelles that control biological growth,...

Synergistic Toxicity of Nitric Oxide and Hydrogen Peroxide Triggers Catastrophic Chromosomal Fragmentation

Professor Andrei Kuzminov and PhD student Pooja Agashe from the Department of Microbiology at the University of Illinois Urbana-Champaign recently explored hydrogen peroxide’s synergistic effects with nitric oxide (NO).

Researchers develop “cytological ruler” to build 3D map of human genome

In a new paper in the Journal of Cell Biology, researchers from the University of Illinois at Urbana-Champaign describe a new technique that can measure the position of every single gene in the nucleus to build a 3D picture of the genome’s organization.