The Christian B. Anfinsen Award, sponsored by The Protein Society, recognizes technological achievement or significant methodological advances in the field of protein science. The recipient of this award in 2020 is Professor Stephen Sligar, professor of Biochemistry and former director of the School of Molecular and Cellular Biology.
Dr. Sligar's academic career has featured the discovery, development, and use of chemical and biophysical tools to understand fundamental problems in protein biochemistry and biophysics. Of relevance to the Anfinsen Award is his development of nanodiscs, which are patches of lipid membrane stabilized by a "belt" of membrane scaffolding proteins. By using nanodiscs, signaling proteins and macromolecular complexes that rely on a membrane can be readily studied in a native bilayer that is solubilized in an aqueous environment. Dr. Sligar's commitment to wide dissemination of the nanodisc technology has led to its use by hundreds of laboratories, amplifying the impact of his advances and broadly benefiting the field of protein science.