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College of Liberal Arts & Sciences School of Molecular & Cellular Biology
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News

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    Virtual predator is self-aware, behaves like living counterpart
    2018-03-02 - Rhanor Gillette and his colleagues built a virtual ocean predator that has simple self-awareness.
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    Cronan Lab: Lipoyl transfer has a "moonlighting" function -- that is, development of a new function while retaining the original function
    2018-02-24 - The study's findings were recently published in PNAS.
  • JKK3web_1.jpg
    Researchers identify new physiological regulators of the one carbon cycle metabolism. The findings were published in Nature Communications.
    2018-02-09 - Professor of Molecular and Integrative Physiology, Jongsook Kim Kemper and the first and co-corresponding author, Young Kim, co-author Sangwon Byun, and colleagues demonstrated that Aromatic Hydrocarbon Receptor (AHR) and the orphan nuclear receptor, Small Heterodimer Partner (SHP), have an unexpected function in regulating one carbon (1C) metabolism in the fed-state. Dysregulation of the 1C...
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    Chung Lab: Prolonged seizure activity causes caspase dependent cleavage and dysfunction of G-protein activated inwardly rectifying potassium channels.
    2018-02-03 - New findings suggest that novel down-regulation of GIRK channels by caspase-3 may contribute to NMDAR-dependent hippocampal atrophy following chronic epileptic seizures
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    Bacterial chromosomal breakdown during isolation highlights the unusual regulation of the surface nucleases
    2018-02-01 - A recent paper in PLOS ONE from the Kuzminov lab illustrated a novel phenomenon, RiCF, aka “RNase-induced chromosomal fragmentation.”
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    Social experience tweaks genome function behavior
    2018-02-01 - What changes in the brain of an animal when its behavior is altered by experience? Research at the University of Illinois led by Professor of Cell and Developmental Biology Lisa Stubbs is working toward an answer to this question by focusing on the collective actions of genes. In a recent Genome Research publication, Stubbs and her colleagues identified and documented the activity of...
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    Structural and computational analyses provide the first view of an activated AMPA receptor. Findings published by the Tajkhorshid and Gouaux labs in Cell.
    2018-01-26 - Using molecular dynamics simulations, the Tajkhorshid lab computationally modeled the complete structure of the active AMPA receptor with hydrated ions moving through an open pore. Together these findings, published in Cell, show how AMPA receptor regulatory proteins enhance the potency of agonists and alter receptor pore properties, and show how neurotransmitter induces structural rearrangements...
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    Brooke Lab: Certain Flu Virus Mutations May Compensate for Fitness Costs of Other Mutations
    2018-01-18 - New research published in PLOS Pathogens finds that unexpected mutations help flu virus retain fitness by counteracting changes needed to dodge the immune system
  • Craigphotoweb.jpg
    Remembering Dr. Craig Mizzen
    2018-01-11 - Dr. Craig Mizzen, Associate Professor of Cell and Developmental Biology, passed away at his home on January 5, 2018, after a long and heroic battle with cancer. He was 61.
  • Headshot of Auinash Kalsotra.
    Exploring RNA’s Binding Role in Liver Disease and Cancer
    2017-12-31 - Kalsotra’s research has focused on RNA, the workhorse cousin of DNA, which makes up the genetic instructions for living things. RNA is often viewed as important for messaging and other functions, taking DNA’s code and transporting it to and carrying out functions in cells. It’s often taken a back seat to DNA in terms of significance.
  • Headshot of Lin-Feng Chen
    Taking a Deep Look at Protein Structures that Contribute to Cancer
    2017-12-31 - Thirteen years ago, when Lin-Feng Chen joined the Department of Biochemistry, he had his sights set on a specific protein that could both contribute to the growth of cancer and be a major factor in boosting the body’s immune system.
  • Headshot of David Shapiro
    Employing the Help of the BHPI Molecule to Boost Anti-Cancer Drug Treatments
    2017-12-31 - For decades, MCB and the University of Illinois have been at the forefront of understanding the role of estrogen and the estrogen receptor (ER) in causing breast cancer. This is essential work: Breast cancer is the most commonly diagnosed cancer in women, affecting roughly one in eight women in the US alone.
  • Healthy human t-cell
    Harnessing and Boosting T-cells to Fight Disease
    2017-12-31 - David Kranz, the Phillip A. Sharp Professor of Biochemistry in the School of Molecular and Cellular Biology, has been involved in T-cell research since working as a postdoctoral researcher at the Massachusetts Institute of Technology, involved in early discoveries about how T-cells might be used to combat a host of diseases, including cancer. Prior to this, he trained as a graduate student at...
  • Dr. Benita Katzenellenbogan, Swanlund Professor of Molecular and Integrative Physiology and Cell and Developmental Biology. Photo by L. Brian Stauffer
    Hitting the (Moving) Target of Drug Resistant Cancers
    2017-12-31 - Benita Katzenellenbogen has delved into the causes and treatments for breast cancer and other hormone-dependent cancers for virtually her entire career. Her tireless work in the field has established her as a world-renowned expert.
  • Alfred Reszka
    Merck researcher's career launched at the same time as CDB
    2017-12-31 - Alfred Reszka’s future was intertwined with the Department of Cell and Developmental Biology in ways he never could have predicted when he came to the University of Illinois in the 1980s. Reszka was one of the first graduate students in the new department, and the connections he made in CDB laid the groundwork for his entire career.

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College of Liberal Arts & Sciences School of Molecular & Cellular Biology
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