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National Institutes of Health (NIH)

Circadian rhythm and the blood-brain barrier

Beckman faculty members Martha Gillette and Hyunjoon Kong received an NIH/DOD grant to study how circadian rhythm affects the blood-brain barrier’s permeability to small molecules and susceptibility to blood leakage. Their team will design a microfluidics-based chip from human stem cells to model...

Study identifies key regulator of cell differentiation

Embryonic stem cells and other pluripotent cells divide rapidly and have the capacity to become nearly any cell type in the body. Scientists have long sought to understand the signals that prompt stem cells to switch off pluripotency and adopt their final functional state.

'Molecular Velcro' enables tissues to sense, react to mechanical force

The Velcro-like cellular proteins that hold cells and tissues together also perform critical functions when they experience increased tension. A new University of Illinois Urbana-Champaign study observed that when tugged upon in a controlled manner, these proteins – called cadherins – communicate...

Twelve faculty, including MCB professor, selected for the 2022 NIH Grant Writing Series mentorship program

The Interdisciplinary Health Sciences Institute (IHSI) is offering the National Institutes of Health (NIH) Grant Writing Series virtually during the 2022 spring semester. The NIH Grant Writing Series prepares faculty to submit their first R01 or other individual investigator proposals to the NIH....

Gene mutation leads to epileptic encephalopathy symptoms, neuron death in mice

Mice with a genetic mutation that’s been observed in patients with epileptic encephalopathy, a severe form of congenital epilepsy, exhibit not only the seizure, developmental and behavioral symptoms of the disorder, but also neural degeneration and inflammation in the brain, University of Illinois...

Association of Computing Machinery recognizes researchers for their novel SARS-CoV2 simulations

Congratulations to the University of Illinois scientists who were part of two teams selected as finalists for a prestigious award that celebrates outstanding achievement in high-performance computing.

Study reveals how bacterial pathogen adapts to nutritional stress

In order to cause disease, the human pathogen Staphylococcus aureus must adapt to the changing host environment. Many of these adaptations are mediated through two-component signal transduction systems (TCSs) that coordinate gene expression in response to environmental stimuli. In a new study...

Water disinfection byproduct disrupts reproductive hormones, damages pituitary in female mice

Chemical disinfection makes water from both natural sources and wastewater streams drinkable; however, the process also creates byproducts, not all of which are understood or regulated. A new study from University of Illinois Urbana-Champaign researchers has found that one byproduct disrupts...

Seeing is believing: Image of primary visual cortex in a mouse wins second place in NIH research image contest

Congratulations to the Tajkhorshid lab and collaborators who created a stunning research image recently highlighted by the National Institutes of Health.

Scientists discover how antibiotics penetrate Gram-negative bacterial cell walls

In a study reported in the journal Chemical Science, researchers developed a new method to determine how antibiotics with specific chemical properties thread their way through tiny pores in the otherwise impenetrable cell envelopes of Gram-negative bacteria.