Microbiology

The latest paper by the Kuzminov lab investigates the mechanism of thymineless death, which is a common mode of action of anti-cancer and anti-bacterial drugs. The findings were published in a paper titled "Sources of thymidine and analogs fueling futile damage-repair cycles and ss-gap accumulation...

Microbiologist Ralph Wolfe contributed to a study of microbes that led to the discovery of a third superkingdom, or domain, of life: the archaea. Wolfe, a professor emeritus of microbiology at the University of Illinois, died March 26 in Urbana. He was 97.

The latest paper by the Kuzminov lab describes the development of a highly sensitive method to probe the nature of DNA replication in E. coli. The findings were published in a paper titled “Near-continuously synthesized leading strands in Escherichia coli are broken by ribonucleotide excision” in...

The latest paper by the Brooke lab investigates the mechanism through which an Influenza A-infected host cell can be rendered resistant to subsequent viral infections. The findings were published in a paper titled “Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic...

Although oxidative stress is a chronic problem, life endures. To understand how oxidative stress damages cells and what their defense mechanisms are, the Imlay lab uses E. coli as a model organism.

Researchers report in a new study that the bacterium Helicobacter pylori – a major contributor to gastritis, ulcers and stomach cancer – resists the body’s immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection.

MCB Collaboration Unravels Bacteria’s Virulence Regulation System

Influenza is one of the most adaptable viruses known to man. By tracking down flu’s weak spots, Christopher Brooke’s lab hopes to aid in the development of new treatments.

Staphylococcus aureus is on the “most wanted list” for the National Institutes of Health, making it a major villain in the microbial world, said Robert B. Gennis, an MCB biochemistry professor. S. aureus also happens to be on the most wanted list in the lab of Thomas Kehl-Fie, MCB...

“Between the realms of agriculture, nature, and humans, the unifying factor is the microbes that exist in each and the specific genes those microbes carry.The IGOH theme at the IGB allows research to be contextualized, and to exist in a space where lab work becomes immediately relevant and...