Molecular & Integrative Physiology (MIP)

Study: Abnormal expression and phosphoinositide regulation of KCNQ/Kv7 channels linked to severe form of genetic epilepsy

2018-08-24

Molecular and integrative physiology professor Hee Jung Chung, postdoctoral fellow Eung Chang Kim, and their colleagues discovered that abnormal expression and phosphoinositide regulation of KCNQ/Kv7 potassium channels underlie neuronal hyperexcitability and injury in early-onset epileptic...

MCB Magazine: Everyone has a cancer story: That's why we do the research

2017-12-18

View the latest edition of MCB Magazine here.

Jongsook Kim Kemper Lab: Novel regulatory pathways in the liver for maintenance of metabolic homeostasis in mice

2018-07-23

The Kemper lab has recently published two high-profile papers on metabolic regulation in the Journal of Clinical Investigation and Nature Communications.

Study: Protein found to be key component in irregularly excited brain cells

2018-07-17

Research scientist Kwan Young Lee, molecular and integrative physiology professor Nien-Pei Tsai, and their colleagues discovered that an overabundance of the tumor suppressor protein p53 in neurons can lead to impaired regulation of neuronal excitability in a mouse model of Fragile X syndrome.

Study reveals a novel target for the treatment of breast cancer

2018-04-06

The proliferation and differentiation of the mammary gland is a process tightly controlled by hormones and growth factors. Dysregulation of the signaling pathways that orchestrate mammary gland development is frequently linked to the excessive, unchecked proliferation associated with breast cancer...

Virtual predator is self-aware, behaves like living counterpart

2018-03-02

Rhanor Gillette and his colleagues built a virtual ocean predator that has simple self-awareness.

Researchers identify new physiological regulators of the one carbon cycle metabolism. The findings were published in Nature Communications.

2018-02-09

Professor of Molecular and Integrative Physiology, Jongsook Kim Kemper and the first and co-corresponding author, Young Kim, co-author Sangwon Byun, and colleagues demonstrated that Aromatic Hydrocarbon Receptor (AHR) and the orphan nuclear receptor, Small Heterodimer Partner (SHP), have an...

Chung Lab: Prolonged seizure activity causes caspase dependent cleavage and dysfunction of G-protein activated inwardly rectifying potassium channels.

2018-02-03

New findings suggest that novel down-regulation of GIRK channels by caspase-3 may contribute to NMDAR-dependent hippocampal atrophy following chronic epileptic seizures

Professor Llano Becomes Professorial Scholar

2017-05-30

Dan Llano was recently appointed the Benjamin R. and Elinor W. Bullock and Edwin E. and Jeanne Bullock Goldberg Professorial Scholar in the Department of Molecular and Integrative Physiology in the School of Molecular and Cellular Biology. Llano is an associate professor in MIP and a member of the...

Hitting the (Moving) Target of Drug Resistant Cancers

2017-12-31

Dr. Benita Katzenellenbogan, Swanlund Professor of Molecular and Integrative Physiology and Cell and Developmental Biology. Photo by L. Brian Stauffer

Benita Katzenellenbogen has delved into the causes and treatments for breast cancer and other hormone-dependent cancers for virtually her entire career. Her tireless work in the field has established her as a world-renowned expert.

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