Image
Assistant Professor Nien-Pei Tsai’s lab has published a study in PLOS Genetics on how a novel epilepsy-associated gene controls neuronal excitability
Epilepsy is a medical condition characterized by spontaneous seizures due to hyperexcitability of brain neurons. Assistant Professor Nien-Pei Tsai, graduate student Jiuhe Zhu and colleagues uncovered that an insufficient function or mutations of a novel epilepsy-associated gene Nedd4-2 leads to...
Image
Neuronal Excitability in Health and Disease
A new era has dawned in understanding neuropathological disorders such as epilepsy, schizophrenia, depression, and autism spectrum disorders. These disorders, traditionally classified in the Diagnostic and Statistical Manual of Mental Disorders by the American Psychiatric Society, are now being re-...
Image
Technological Breakthroughs Transform Biological Inquiry in Neuroscience
The infinitely complex workings of the human brain have intrigued researchers for centuries. Our understanding of its workings have been limited, not by our curiosity, but by our tools. Now, with the growth of new molecular biology and genomics approaches, big data, and engineering advances that...
Image
Ceman lab in Cell Reports: How FMRP interacts with RNA helicase MOV10 to regulate translation
The Ceman laboratory, with lead authors Phil Kenny and Miri Kim, have shown that FMRP is able to facilitate or suppress the translation of a subset of its target mRNAs by its interaction with the RNA helicase MOV10.
Image
Fragile X Syndrome
In this article, Associate Professor of Cell and Developmental Biology Stephanie Ceman discusses her research on Fragile X Syndrome.