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Neurological and Behavioral Disorders

Recent research from Christian-Hinman lab provides foundation for new experimental designs to study epilepsy

Patients with temporal lobe epilepsy, the most common form of focal epilepsy, often have seizures that start from one side of the hippocampus and not the other. Such patients may also experience complications such as cognitive impairment and reproductive endocrine disruption. Although it’s been...

New ultrasound tool measures blood flow, images microvasculature in the brain

Researchers at the Beckman Institute developed a technique for producing super-resolution ultrasound images of tissue microvasculature in just a fraction of the time previously needed. Their work could enable future research into the neurovascular mechanisms behind conditions like Alzheimer’s...

Decoding Life with MCB: Eating Disorders

Life is extraordinary. So is the work we do. In a brand new podcast series, Decoding Life with MCB, the School of Molecular and Cellular Biology at the University of Illinois Urbana-Champaign explores the impact of our students, faculty, staff, and alumni in each episode.

Research illuminates balancing act for protein linked to Fragile X Syndrome and Alzheimer's disease

A new study by researchers at the University of Illinois Urbana-Champaign suggests the overexpression of a particular gene could serve as a risk factor for Alzheimer’s disease. Their findings could also lead to better understandings of the links between Alzheimer’s disease, Fragile X Syndrome, and...

MCB team identifies compound with potent antiseizure effects

Researchers studying epileptic seizures of the temporal lobe – the most common type of epilepsy – discovered a compound that reduces seizures in the hippocampus, a brain region where many such seizures originate. The compound, known as TC-2153, lessened the severity of seizures in mice. The...

Professor Catherine Christian-Hinman: Connecting estrogen to epilepsy

Meet MCB: Dr. Christian-Hinman’s lab focuses on understanding the neural mechanisms linking epilepsy and comorbid reproductive endocrine disorder.

Gene mutation leads to epileptic encephalopathy symptoms, neuron death in mice

Mice with a genetic mutation that’s been observed in patients with epileptic encephalopathy, a severe form of congenital epilepsy, exhibit not only the seizure, developmental and behavioral symptoms of the disorder, but also neural degeneration and inflammation in the brain, University of Illinois...

Detailed map of ion-channel structure could steer development of new therapeutic strategies for epilepsy

Researchers at the University of Illinois Urbana-Champaign are hopeful their findings on the gating mechanisms behind epilepsy-associated potassium channels could provide a foundation for new therapeutic strategies for treating epilepsy, especially in young patients. Their research was recently...

Uncovering the Critical Function of Drg1 in Protein Synthesis

Biochemistry researchers at the University of Illinois Urbana-Champaign are conducting trailblazing work on a group of conserved proteins that are directly related to abnormal cell proliferation and developmental and neurological disorders. In a new article published in Cell Reports, biochemistry...

New faculty member to further explore research linking brain receptor to increased height, early puberty

For the past few decades, scientists have observed a trend of increased height and younger age of puberty onset in humans. Now, research outlining a new pathway in humans linking body fat to puberty onset and growth could provide an explanation as to why these changes are occurring. Their findings...